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Results: 1 to 20 of 113

1.

Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking.

Stanley AM, Carvalho P, Rapoport T.

FEBS Lett. 2011 May 6;585(9):1281-6. doi: 10.1016/j.febslet.2011.04.009. Epub 2011 Apr 8.

PMID:
21486563
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.

Carvalho P, Stanley AM, Rapoport TA.

Cell. 2010 Nov 12;143(4):579-91. doi: 10.1016/j.cell.2010.10.028.

PMID:
21074049
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Carvalho P, Goder V, Rapoport TA.

Cell. 2006 Jul 28;126(2):361-73.

PMID:
16873066
[PubMed - indexed for MEDLINE]
Free Article
4.

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

Gauss R, Jarosch E, Sommer T, Hirsch C.

Nat Cell Biol. 2006 Aug;8(8):849-54. Epub 2006 Jul 16.

PMID:
16845381
[PubMed - indexed for MEDLINE]
5.

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation.

Denic V, Quan EM, Weissman JS.

Cell. 2006 Jul 28;126(2):349-59.

PMID:
16873065
[PubMed - indexed for MEDLINE]
Free Article
6.

Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation.

Izawa T, Nagai H, Endo T, Nishikawa S.

Mol Biol Cell. 2012 Apr;23(7):1283-93. doi: 10.1091/mbc.E11-08-0722. Epub 2012 Feb 1.

PMID:
22298424
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Modularity of the Hrd1 ERAD complex underlies its diverse client range.

Kanehara K, Xie W, Ng DT.

J Cell Biol. 2010 Mar 8;188(5):707-16. doi: 10.1083/jcb.200907055.

PMID:
20212318
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.

Gardner RG, Shearer AG, Hampton RY.

Mol Cell Biol. 2001 Jul;21(13):4276-91.

PMID:
11390656
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Have you HRD? Understanding ERAD is DOAble!

Ismail N, Ng DT.

Cell. 2006 Jul 28;126(2):237-9.

PMID:
16873052
[PubMed - indexed for MEDLINE]
Free Article
10.

Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation.

Plemper RK, Bordallo J, Deak PM, Taxis C, Hitt R, Wolf DH.

J Cell Sci. 1999 Nov;112 ( Pt 22):4123-34.

PMID:
10547371
[PubMed - indexed for MEDLINE]
Free Article
11.

Sec61p is part of the endoplasmic reticulum-associated degradation machinery.

Schäfer A, Wolf DH.

EMBO J. 2009 Oct 7;28(19):2874-84. doi: 10.1038/emboj.2009.231. Epub 2009 Aug 20.

PMID:
19696741
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Yos9, a control protein for misfolded glycosylated and non-glycosylated proteins in ERAD.

Benitez EM, Stolz A, Wolf DH.

FEBS Lett. 2011 Oct 3;585(19):3015-9. doi: 10.1016/j.febslet.2011.08.021. Epub 2011 Aug 23.

PMID:
21871892
[PubMed - indexed for MEDLINE]
Free Article
13.

A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation.

Kostova Z, Mariano J, Scholz S, Koenig C, Weissman AM.

J Cell Sci. 2009 May 1;122(Pt 9):1374-81. doi: 10.1242/jcs.044255. Epub 2009 Apr 14.

PMID:
19366730
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dfm1 forms distinct complexes with Cdc48 and the ER ubiquitin ligases and is required for ERAD.

Stolz A, Schweizer RS, Schäfer A, Wolf DH.

Traffic. 2010 Oct;11(10):1363-9. doi: 10.1111/j.1600-0854.2010.01093.x.

PMID:
20579315
[PubMed - indexed for MEDLINE]
15.

Usa1p is required for optimal function and regulation of the Hrd1p endoplasmic reticulum-associated degradation ubiquitin ligase.

Carroll SM, Hampton RY.

J Biol Chem. 2010 Feb 19;285(8):5146-56. doi: 10.1074/jbc.M109.067876. Epub 2009 Nov 24.

PMID:
19940128
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase.

Sato BK, Schulz D, Do PH, Hampton RY.

Mol Cell. 2009 Apr 24;34(2):212-22. doi: 10.1016/j.molcel.2009.03.010.

PMID:
19394298
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.

Clerc S, Hirsch C, Oggier DM, Deprez P, Jakob C, Sommer T, Aebi M.

J Cell Biol. 2009 Jan 12;184(1):159-72. doi: 10.1083/jcb.200809198. Epub 2009 Jan 5.

PMID:
19124653
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Intrinsic conformational determinants signal protein misfolding to the Hrd1/Htm1 endoplasmic reticulum-associated degradation system.

Xie W, Kanehara K, Sayeed A, Ng DT.

Mol Biol Cell. 2009 Jul;20(14):3317-29. doi: 10.1091/mbc.E09-03-0231. Epub 2009 May 20.

PMID:
19458187
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Endoplasmic reticulum-associated degradation of cytochrome P450 CYP3A4 in Saccharomyces cerevisiae: further characterization of cellular participants and structural determinants.

Liao M, Faouzi S, Karyakin A, Correia MA.

Mol Pharmacol. 2006 Jun;69(6):1897-904. Epub 2006 Mar 23.

PMID:
16556771
[PubMed - indexed for MEDLINE]
Free Article
20.

A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.

Nakatsukasa K, Brodsky JL, Kamura T.

Mol Biol Cell. 2013 Jun;24(11):1765-75, S1-8. doi: 10.1091/mbc.E12-12-0907. Epub 2013 Mar 27.

PMID:
23536702
[PubMed - indexed for MEDLINE]
Free PMC Article

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