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Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters.

Younger ST, Corey DR.

Nucleic Acids Res. 2011 Jul;39(13):5682-91. doi: 10.1093/nar/gkr155. Epub 2011 Mar 22.


Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter.

Chu Y, Yue X, Younger ST, Janowski BA, Corey DR.

Nucleic Acids Res. 2010 Nov;38(21):7736-48. doi: 10.1093/nar/gkq648. Epub 2010 Jul 30.


MicroRNA-directed transcriptional gene silencing in mammalian cells.

Kim DH, Saetrom P, Snøve O Jr, Rossi JJ.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16230-5. doi: 10.1073/pnas.0808830105. Epub 2008 Oct 13.


Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer.

Wee EJ, Peters K, Nair SS, Hulf T, Stein S, Wagner S, Bailey P, Lee SY, Qu WJ, Brewster B, French JD, Dobrovic A, Francis GD, Clark SJ, Brown MA.

Oncogene. 2012 Sep 20;31(38):4182-95. doi: 10.1038/onc.2011.584. Epub 2012 Jan 9.


Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini.

Younger ST, Corey DR.

Mol Biosyst. 2011 Aug;7(8):2383-8. doi: 10.1039/c1mb05090g. Epub 2011 May 18.


Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells.

Tan Y, Zhang B, Wu T, Skogerbø G, Zhu X, Guo X, He S, Chen R.

BMC Mol Biol. 2009 Feb 22;10:12. doi: 10.1186/1471-2199-10-12.


Transcriptional silencing by hairpin RNAs complementary to a gene promoter.

Chu Y, Kalantari R, Dodd DW, Corey DR.

Nucleic Acid Ther. 2012 Jun;22(3):147-51. doi: 10.1089/nat.2012.0360.


Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development.

Rivas MA, Venturutti L, Huang YW, Schillaci R, Huang TH, Elizalde PV.

Breast Cancer Res. 2012 May 14;14(3):R77.


Optimization of a microRNA expression vector for function analysis of microRNA.

Furukawa N, Sakurai F, Katayama K, Seki N, Kawabata K, Mizuguchi H.

J Control Release. 2011 Feb 28;150(1):94-101. doi: 10.1016/j.jconrel.2010.12.001. Epub 2010 Dec 10.


Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.

Janowski BA, Huffman KE, Schwartz JC, Ram R, Nordsell R, Shames DS, Minna JD, Corey DR.

Nat Struct Mol Biol. 2006 Sep;13(9):787-92. Epub 2006 Aug 27.


Upregulation of Cyclin B1 by miRNA and its implications in cancer.

Huang V, Place RF, Portnoy V, Wang J, Qi Z, Jia Z, Yu A, Shuman M, Yu J, Li LC.

Nucleic Acids Res. 2012 Feb;40(4):1695-707. doi: 10.1093/nar/gkr934. Epub 2011 Nov 3.


Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking.

Subtil-Rodríguez A, Millán-Ariño L, Quiles I, Ballaré C, Beato M, Jordan A.

Mol Cell Biol. 2008 Jun;28(11):3830-49. doi: 10.1128/MCB.01217-07. Epub 2008 Mar 31.


Predicting potential miRNA target sites within gene promoters.

Younger ST, Pertsemlidis A, Corey DR.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3791-4. doi: 10.1016/j.bmcl.2009.04.032. Epub 2009 Apr 18.


Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells.

Benhamed M, Herbig U, Ye T, Dejean A, Bischof O.

Nat Cell Biol. 2012 Feb 26;14(3):266-75. doi: 10.1038/ncb2443.


An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma.

Luo Z, Zhang L, Li Z, Li X, Li G, Yu H, Jiang C, Dai Y, Guo X, Xiang J, Li G.

BMC Med Genomics. 2012 Jan 19;5:3. doi: 10.1186/1755-8794-5-3.


miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.

Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM.

Blood. 2009 Oct 8;114(15):3255-64. doi: 10.1182/blood-2009-06-229898. Epub 2009 Aug 19.


Activating gene expression in mammalian cells with promoter-targeted duplex RNAs.

Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR.

Nat Chem Biol. 2007 Mar;3(3):166-73. Epub 2007 Jan 28.


MicroRNA-373 induces expression of genes with complementary promoter sequences.

Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1608-13. doi: 10.1073/pnas.0707594105. Epub 2008 Jan 28.


Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer.

Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, Maruyama R, Kai M, Yamano HO, Sasaki Y, Tokino T, Shinomura Y, Imai K, Toyota M.

Cancer Res. 2011 Sep 1;71(17):5646-58. doi: 10.1158/0008-5472.CAN-11-1076. Epub 2011 Jul 6.

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