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Peroxisome proliferator-activated receptor agonist treatment of alcohol-induced hepatic insulin resistance.

de la Monte SM, Pang M, Chaudhry R, Duan K, Longato L, Carter J, Ouh J, Wands JR.

Hepatol Res. 2011 Apr;41(4):386-98. doi: 10.1111/j.1872-034X.2011.00775.x. Epub 2011 Feb 24.


Structural Correlates of PPAR Agonist Rescue of Experimental Chronic Alcohol-Induced Steatohepatitis.

Ramirez T, Tong M, Ayala CA, Monfils PR, McMillan PN, Zabala V, Wands JR, de la Monte SM.

J Clin Exp Pathol. 2012 Jun;2(4). pii: 114.


Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment.

Ramirez T, Tong M, Chen WC, Nguyen QG, Wands JR, de la Monte SM.

J Gastroenterol Hepatol. 2013 Jan;28(1):179-87. doi: 10.1111/j.1440-1746.2012.07256.x.


Chronic Ethanol-Induced Impairment of Wnt/β-Catenin Signaling is Attenuated by PPAR-δ Agonist.

Xu CQ, de la Monte SM, Tong M, Huang CK, Kim M.

Alcohol Clin Exp Res. 2015 Jun;39(6):969-79. doi: 10.1111/acer.12727. Epub 2015 Apr 23.


PPARdelta agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair.

Pang M, de la Monte SM, Longato L, Tong M, He J, Chaudhry R, Duan K, Ouh J, Wands JR.

J Hepatol. 2009 Jun;50(6):1192-201. doi: 10.1016/j.jhep.2009.01.021. Epub 2009 Mar 20.


Insulin resistance in experimental alcohol-induced liver disease.

de la Monte SM, Yeon JE, Tong M, Longato L, Chaudhry R, Pang MY, Duan K, Wands JR.

J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e477-86. doi: 10.1111/j.1440-1746.2008.05339.x. Epub 2008 May 26.


Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats.

Shen L, Liu Z, Gong J, Zhang L, Wang L, Magdalou J, Chen L, Wang H.

Toxicol Appl Pharmacol. 2014 Jan 15;274(2):263-73. doi: 10.1016/j.taap.2013.11.009. Epub 2013 Nov 22.


Ceramide inhibitor myriocin restores insulin/insulin growth factor signaling for liver remodeling in experimental alcohol-related steatohepatitis.

Lizarazo D, Zabala V, Tong M, Longato L, de la Monte SM.

J Gastroenterol Hepatol. 2013 Oct;28(10):1660-8. doi: 10.1111/jgh.12291.


Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis.

Setshedi M, Longato L, Petersen DR, Ronis M, Chen WC, Wands JR, de la Monte SM.

Alcohol Clin Exp Res. 2011 Dec;35(12):2139-51. doi: 10.1111/j.1530-0277.2011.01569.x. Epub 2011 Jul 25.


Peroxisome proliferator-activated receptor δ agonist attenuates hepatic steatosis by anti-inflammatory mechanism.

Lee MY, Choi R, Kim HM, Cho EJ, Kim BH, Choi YS, Naowaboot J, Lee EY, Yang YC, Shin JY, Shin YG, Chung CH.

Exp Mol Med. 2012 Oct 31;44(10):578-85. doi: 10.3858/emm.2012.44.10.066.


Involvement of insulin resistance in the protective effect of metformin against alcoholic liver injury.

Zhu Z, Jiang Z, Zhou J, Zhou D, Wang W, Zhao C, Zhen Z, Nanji AA.

Alcohol Clin Exp Res. 2014 Jun;38(6):1510-9. doi: 10.1111/acer.12418. Epub 2014 May 5.


Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease.

Souza-Mello V.

World J Hepatol. 2015 May 18;7(8):1012-9. doi: 10.4254/wjh.v7.i8.1012.


Synergistic premalignant effects of chronic ethanol exposure and insulin receptor substrate-1 overexpression in liver.

Longato L, de la Monte S, Califano S, Wands JR.

Hepatol Res. 2008 Sep;38(9):940-53. doi: 10.1111/j.1872-034X.2008.00336.x. Epub 2008 Mar 10.


Impaired insulin/IGF signaling in experimental alcohol-related myopathy.

Nguyen VA, Le T, Tong M, Silbermann E, Gundogan F, de la Monte SM.

Nutrients. 2012 Aug;4(8):1058-75. Epub 2012 Aug 20.


Experimental alcohol-related peripheral neuropathy: role of insulin/IGF resistance.

Nguyen VA, Le T, Tong M, Mellion M, Gilchrist J, de la Monte SM.

Nutrients. 2012 Aug;4(8):1042-57. Epub 2012 Aug 17.


Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.

Lebrun V, Molendi-Coste O, Lanthier N, Sempoux C, Cani PD, van Rooijen N, Stärkel P, Horsmans Y, Leclercq IA.

Clin Sci (Lond). 2013 Dec;125(11):501-11. doi: 10.1042/CS20130064.


Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migration.

de la Monte SM, Tong M, Carlson RI, Carter JJ, Longato L, Silbermann E, Wands JR.

Alcohol. 2009 May;43(3):225-40. doi: 10.1016/j.alcohol.2008.09.009.

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