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Results: 1 to 20 of 199

1.

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

Yan XJ, Xu J, Gu ZH, Pan CM, Lu G, Shen Y, Shi JY, Zhu YM, Tang L, Zhang XW, Liang WX, Mi JQ, Song HD, Li KQ, Chen Z, Chen SJ.

Nat Genet. 2011 Mar 13;43(4):309-15. doi: 10.1038/ng.788.

PMID:
21399634
[PubMed - indexed for MEDLINE]
2.

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

Renneville A, Boissel N, Nibourel O, Berthon C, Helevaut N, Gardin C, Cayuela JM, Hayette S, Reman O, Contentin N, Bordessoule D, Pautas C, Botton Sd, Revel Td, Terre C, Fenaux P, Thomas X, Castaigne S, Dombret H, Preudhomme C.

Leukemia. 2012 Jun;26(6):1247-54. doi: 10.1038/leu.2011.382. Epub 2012 Jan 13.

PMID:
22289988
[PubMed - indexed for MEDLINE]
3.

DNMT3A mutations in acute myeloid leukemia.

Shah MY, Licht JD.

Nat Genet. 2011 Mar 29;43(4):289-90. doi: 10.1038/ng0411-289.

PMID:
21445072
[PubMed - indexed for MEDLINE]
4.

Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.

Thol F, Damm F, Lüdeking A, Winschel C, Wagner K, Morgan M, Yun H, Göhring G, Schlegelberger B, Hoelzer D, Lübbert M, Kanz L, Fiedler W, Kirchner H, Heil G, Krauter J, Ganser A, Heuser M.

J Clin Oncol. 2011 Jul 20;29(21):2889-96. doi: 10.1200/JCO.2011.35.4894. Epub 2011 Jun 13.

PMID:
21670448
[PubMed - indexed for MEDLINE]
Free Article
5.

Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia.

Ribeiro AF, Pratcorona M, Erpelinck-Verschueren C, Rockova V, Sanders M, Abbas S, Figueroa ME, Zeilemaker A, Melnick A, Löwenberg B, Valk PJ, Delwel R.

Blood. 2012 Jun 14;119(24):5824-31. doi: 10.1182/blood-2011-07-367961. Epub 2012 Apr 5.

PMID:
22490330
[PubMed - indexed for MEDLINE]
Free Article
6.

[DNMT3A gene mutations in acute myeloid leukemia].

Chen YM, Lu QY.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2011 Dec;19(6):1556-60. Review. Chinese.

PMID:
22169324
[PubMed - indexed for MEDLINE]
7.

Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.

Jost E, Lin Q, Weidner CI, Wilop S, Hoffmann M, Walenda T, Schemionek M, Herrmann O, Zenke M, Brümmendorf TH, Koschmieder S, Wagner W.

Leukemia. 2014 Jun;28(6):1227-34. doi: 10.1038/leu.2013.362. Epub 2013 Nov 27.

PMID:
24280869
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

[Mutational detection of full-length mixed lineage leukemia gene in patients with de novo AML-M4 and M5].

Wang QR, Shi JY, Shi L, Chen SJ.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Feb;20(1):12-7. Chinese.

PMID:
22391156
[PubMed - indexed for MEDLINE]
9.

Decreased DNA methylation in acute myeloid leukemia patients with DNMT3A mutations and prognostic implications of DNA methylation.

Hájková H, Marková J, Haškovec C, Sárová I, Fuchs O, Kostečka A, Cetkovský P, Michalová K, Schwarz J.

Leuk Res. 2012 Sep;36(9):1128-33. doi: 10.1016/j.leukres.2012.05.012. Epub 2012 Jun 28.

PMID:
22749068
[PubMed - indexed for MEDLINE]
10.

Recurrent DNMT3A R882 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

Lin J, Yao DM, Qian J, Chen Q, Qian W, Li Y, Yang J, Wang CZ, Chai HY, Qian Z, Xiao GF, Xu WR.

PLoS One. 2011;6(10):e26906. doi: 10.1371/journal.pone.0026906. Epub 2011 Oct 31.

PMID:
22066015
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

DNMT3A mutation is a poor prognosis biomarker in AML: results of a meta-analysis of 4500 AML patients.

Shivarov V, Gueorguieva R, Stoimenov A, Tiu R.

Leuk Res. 2013 Nov;37(11):1445-50. doi: 10.1016/j.leukres.2013.07.032. Epub 2013 Aug 5.

PMID:
23962568
[PubMed - indexed for MEDLINE]
12.

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.

Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Kandoth C, Baty J, Westervelt P, DiPersio JF, Mardis ER, Wilson RK, Ley TJ, Graubert TA.

Leukemia. 2011 Jul;25(7):1153-8. doi: 10.1038/leu.2011.44. Epub 2011 Mar 18.

PMID:
21415852
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers.

Russler-Germain DA, Spencer DH, Young MA, Lamprecht TL, Miller CA, Fulton R, Meyer MR, Erdmann-Gilmore P, Townsend RR, Wilson RK, Ley TJ.

Cancer Cell. 2014 Apr 14;25(4):442-54. doi: 10.1016/j.ccr.2014.02.010. Epub 2014 Mar 20.

PMID:
24656771
[PubMed - indexed for MEDLINE]
14.

DNMT3A mutations in acute myeloid leukemia.

Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE, Kandoth C, Payton JE, Baty J, Welch J, Harris CC, Lichti CF, Townsend RR, Fulton RS, Dooling DJ, Koboldt DC, Schmidt H, Zhang Q, Osborne JR, Lin L, O'Laughlin M, McMichael JF, Delehaunty KD, McGrath SD, Fulton LA, Magrini VJ, Vickery TL, Hundal J, Cook LL, Conyers JJ, Swift GW, Reed JP, Alldredge PA, Wylie T, Walker J, Kalicki J, Watson MA, Heath S, Shannon WD, Varghese N, Nagarajan R, Westervelt P, Tomasson MH, Link DC, Graubert TA, DiPersio JF, Mardis ER, Wilson RK.

N Engl J Med. 2010 Dec 16;363(25):2424-33. doi: 10.1056/NEJMoa1005143. Epub 2010 Nov 10.

PMID:
21067377
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation.

Holz-Schietinger C, Matje DM, Reich NO.

J Biol Chem. 2012 Sep 7;287(37):30941-51. doi: 10.1074/jbc.M112.366625. Epub 2012 Jun 21.

PMID:
22722925
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.

Kim SJ, Zhao H, Hardikar S, Singh AK, Goodell MA, Chen T.

Blood. 2013 Dec 12;122(25):4086-9. doi: 10.1182/blood-2013-02-483487. Epub 2013 Oct 28.

PMID:
24167195
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

[Analysis of DNMT3a gene mutations in acute myelogenous leukemia].

Qiao C, Sun C, Zhang SJ, Qian SX, Qian XF, Miao KR, Zhu HY, Hong M, Li JY.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2011 Apr;19(2):303-7. Chinese.

PMID:
21518476
[PubMed - indexed for MEDLINE]
18.

ALL-1 gene rearrangements in acute myeloid leukemia: association with M4-M5 French-American-British classification subtypes and young age.

Cimino G, Rapanotti MC, Elia L, Biondi A, Fizzotti M, Testi AM, Tosti S, Croce CM, Canaani E, Mandelli F, et al.

Cancer Res. 1995 Apr 15;55(8):1625-8.

PMID:
7712464
[PubMed - indexed for MEDLINE]
Free Article
19.

Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience.

LaRochelle O, Bertoli S, Vergez F, Sarry JE, Mansat-De Mas V, Dobbelstein S, Dastugue N, Strzelecki AC, Cavelier C, Creancier L, Pillon A, Kruczynski A, Demur C, Sarry A, Huguet F, Huynh A, Récher C, Delabesse E.

Oncotarget. 2011 Nov;2(11):850-61.

PMID:
22081665
[PubMed - indexed for MEDLINE]
Free PMC Article
20.
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