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Items: 1 to 20 of 102

1.

Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.

San Luis B, Sondgeroth B, Nassar N, Carpino N.

J Biol Chem. 2011 May 6;286(18):15943-54. doi: 10.1074/jbc.M110.177634. Epub 2011 Mar 10.

3.

A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling.

Mikhailik A, Ford B, Keller J, Chen Y, Nassar N, Carpino N.

Mol Cell. 2007 Aug 3;27(3):486-97.

4.

Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2.

Carpino N, Turner S, Mekala D, Takahashi Y, Zang H, Geiger TL, Doherty P, Ihle JN.

Immunity. 2004 Jan;20(1):37-46.

5.

The Sts proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways.

Carpino N, Chen Y, Nassar N, Oh HW.

Mol Immunol. 2009 Oct;46(16):3224-31. doi: 10.1016/j.molimm.2009.08.015. Epub 2009 Sep 5.

7.

Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.

Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.

J Biol Chem. 2001 Nov 30;276(48):45175-83. Epub 2001 Sep 25.

8.

Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.

Brockdorff J, Williams S, Couture C, Mustelin T.

Eur J Immunol. 1999 Aug;29(8):2539-50.

9.

Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.

Chen Y, Jakoncic J, Carpino N, Nassar N.

Biochemistry. 2009 Mar 3;48(8):1681-90. doi: 10.1021/bi802219n.

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12.

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.

Qian D, Mollenauer MN, Weiss A.

J Exp Med. 1996 Feb 1;183(2):611-20.

13.

Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase.

Latour S, Fournel M, Veillette A.

Mol Cell Biol. 1997 Aug;17(8):4434-41.

14.

The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.

Sjölin-Goodfellow H, Frushicheva MP, Ji Q, Cheng DA, Kadlecek TA, Cantor AJ, Kuriyan J, Chakraborty AK, Salomon AR, Weiss A.

Sci Signal. 2015 May 19;8(377):ra49. doi: 10.1126/scisignal.2005596.

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17.

Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4.

Kim KD, Choi JM, Chae WJ, Lee SK.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):355-60. doi: 10.1016/j.bbrc.2009.02.046. Epub 2009 Feb 20.

PMID:
19230824
20.

Fine-tuning of proximal TCR signaling by ZAP-70 tyrosine residues in Jurkat cells.

Szabo M, Czompoly T, Kvell K, Talaber G, Bartis D, Nemeth P, Berki T, Boldizsar F.

Int Immunol. 2012 Feb;24(2):79-87. doi: 10.1093/intimm/dxr105. Epub 2011 Dec 29.

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