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Results: 1 to 20 of 112

1.

EDD inhibits ATM-mediated phosphorylation of p53.

Ling S, Lin WC.

J Biol Chem. 2011 Apr 29;286(17):14972-82. doi: 10.1074/jbc.M110.182527. Epub 2011 Mar 7.

PMID:
21383020
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.

Fabbro M, Savage K, Hobson K, Deans AJ, Powell SN, McArthur GA, Khanna KK.

J Biol Chem. 2004 Jul 23;279(30):31251-8. Epub 2004 May 24.

PMID:
15159397
[PubMed - indexed for MEDLINE]
Free Article
3.

ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.

Cheng Q, Chen L, Li Z, Lane WS, Chen J.

EMBO J. 2009 Dec 16;28(24):3857-67. doi: 10.1038/emboj.2009.294. Epub .

PMID:
19816404
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.

Dornan D, Shimizu H, Mah A, Dudhela T, Eby M, O'rourke K, Seshagiri S, Dixit VM.

Science. 2006 Aug 25;313(5790):1122-6.

PMID:
16931761
[PubMed - indexed for MEDLINE]
Free Article
5.

Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.

Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL.

Int J Cancer. 2006 Feb 15;118(4):857-68.

PMID:
16152627
[PubMed - indexed for MEDLINE]
6.

Mechanism of p53 stabilization by ATM after DNA damage.

Cheng Q, Chen J.

Cell Cycle. 2010 Feb 1;9(3):472-8.

PMID:
20081365
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest.

Chae HD, Kim SY, Park SE, Kim J, Shin DY.

Exp Mol Med. 2012 Mar 31;44(3):236-40. doi: 10.3858/emm.2012.44.3.018.

PMID:
22198295
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.

Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW.

J Exp Med. 2012 Jan 16;209(1):173-86. doi: 10.1084/jem.20111363. Epub 2012 Jan 2.

PMID:
22213803
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.

Tang J, Agrawal T, Cheng Q, Qu L, Brewer MD, Chen J, Yang X.

PLoS One. 2013;8(2):e55813. doi: 10.1371/journal.pone.0055813. Epub 2013 Feb 6. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/032b026d-5bcf-4c1b-aa15-65c226a53818.

PMID:
23405218
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.

Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, Wei W.

Oncotarget. 2012 Sep;3(9):1026-35.

PMID:
22976441
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.

Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.

Mol Cell Biol. 2005 Jan;25(2):661-70.

PMID:
15632067
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.

Winter M, Sombroek D, Dauth I, Moehlenbrink J, Scheuermann K, Crone J, Hofmann TG.

Nat Cell Biol. 2008 Jul;10(7):812-24. doi: 10.1038/ncb1743. Epub 2008 Jun 8.

PMID:
18536714
[PubMed - indexed for MEDLINE]
13.

Etoposide induces G2/M arrest and apoptosis in neural progenitor cells via DNA damage and an ATM/p53-related pathway.

Nam C, Doi K, Nakayama H.

Histol Histopathol. 2010 Apr;25(4):485-93.

PMID:
20183801
[PubMed - indexed for MEDLINE]
14.

Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1.

Shin YC, Nakamura H, Liang X, Feng P, Chang H, Kowalik TF, Jung JU.

J Virol. 2006 Mar;80(5):2257-66.

PMID:
16474133
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.

Yoon JH, Ahn SG, Lee BH, Jung SH, Oh SH.

Biochem Pharmacol. 2012 Mar 15;83(6):747-57. doi: 10.1016/j.bcp.2011.12.029. Epub 2011 Dec 29.

PMID:
22226932
[PubMed - indexed for MEDLINE]
16.

Kotomolide A arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells.

Chen CY, Hsu YL, Tsai YC, Kuo PL.

Food Chem Toxicol. 2008 Jul;46(7):2476-84. doi: 10.1016/j.fct.2008.04.016. Epub 2008 Apr 22.

PMID:
18511169
[PubMed - indexed for MEDLINE]
17.

Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.

Kurose A, Tanaka T, Huang X, Traganos F, Dai W, Darzynkiewicz Z.

Cytometry A. 2006 Apr;69(4):212-21.

PMID:
16528719
[PubMed - indexed for MEDLINE]
Free Article
18.

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y.

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. Epub 2005 Mar 23.

PMID:
15788536
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.

Chen L, Gilkes DM, Pan Y, Lane WS, Chen J.

EMBO J. 2005 Oct 5;24(19):3411-22. Epub 2005 Sep 15.

PMID:
16163388
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Chromatin modifying protein 1A (Chmp1A) of the endosomal sorting complex required for transport (ESCRT)-III family activates ataxia telangiectasia mutated (ATM) for PanC-1 cell growth inhibition.

Manohar S, Harlow M, Nguyen H, Li J, Hankins GR, Park M.

Cell Cycle. 2011 Aug 1;10(15):2529-39. Epub 2011 Aug 1.

PMID:
21705858
[PubMed - indexed for MEDLINE]
Free PMC Article

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