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Results: 1 to 20 of 312

1.

Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins.

Oikawa D, Kimata Y.

Methods Enzymol. 2011;490:195-216. doi: 10.1016/B978-0-12-385114-7.00012-X.

PMID:
21266252
[PubMed - indexed for MEDLINE]
2.

Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.

Kimata Y, Kimata YI, Shimizu Y, Abe H, Farcasanu IC, Takeuchi M, Rose MD, Kohno K.

Mol Biol Cell. 2003 Jun;14(6):2559-69. Epub 2003 Feb 21.

PMID:
12808051
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.

Oikawa D, Kimata Y, Kohno K, Iwawaki T.

Exp Cell Res. 2009 Sep 10;315(15):2496-504. doi: 10.1016/j.yexcr.2009.06.009. Epub 2009 Jun 16.

PMID:
19538957
[PubMed - indexed for MEDLINE]
4.

Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1.

Oikawa D, Kimata Y, Kohno K.

J Cell Sci. 2007 May 1;120(Pt 9):1681-8.

PMID:
17452628
[PubMed - indexed for MEDLINE]
Free Article
5.

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1.

Kimata Y, Oikawa D, Shimizu Y, Ishiwata-Kimata Y, Kohno K.

J Cell Biol. 2004 Nov 8;167(3):445-56. Epub 2004 Nov 1.

PMID:
15520230
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ.

Science. 2006 Apr 28;312(5773):572-6.

PMID:
16645094
[PubMed - indexed for MEDLINE]
Free Article
7.

BiP-bound and nonclustered mode of Ire1 evokes a weak but sustained unfolded protein response.

Ishiwata-Kimata Y, Promlek T, Kohno K, Kimata Y.

Genes Cells. 2013 Apr;18(4):288-301. doi: 10.1111/gtc.12035. Epub 2013 Feb 6.

PMID:
23387983
[PubMed - indexed for MEDLINE]
8.

IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.

Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.

Cell Signal. 2013 Nov;25(11):2136-46. doi: 10.1016/j.cellsig.2013.06.011. Epub 2013 Jun 29.

PMID:
23816533
[PubMed - indexed for MEDLINE]
9.

BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response.

Pincus D, Chevalier MW, Aragón T, van Anken E, Vidal SE, El-Samad H, Walter P.

PLoS Biol. 2010 Jul 6;8(7):e1000415. doi: 10.1371/journal.pbio.1000415.

PMID:
20625545
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

ER stress signaling by regulated splicing: IRE1/HAC1/XBP1.

Back SH, Schröder M, Lee K, Zhang K, Kaufman RJ.

Methods. 2005 Apr;35(4):395-416.

PMID:
15804613
[PubMed - indexed for MEDLINE]
11.

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways.

Promlek T, Ishiwata-Kimata Y, Shido M, Sakuramoto M, Kohno K, Kimata Y.

Mol Biol Cell. 2011 Sep;22(18):3520-32. doi: 10.1091/mbc.E11-04-0295. Epub 2011 Jul 20.

PMID:
21775630
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.

Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ.

Genes Dev. 2002 Feb 15;16(4):452-66.

PMID:
11850408
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Cloning of mammalian Ire1 reveals diversity in the ER stress responses.

Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D.

EMBO J. 1998 Oct 1;17(19):5708-17.

PMID:
9755171
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

PI 3-kinase regulatory subunits as regulators of the unfolded protein response.

Winnay JN, Kahn CR.

Methods Enzymol. 2011;490:147-58. doi: 10.1016/B978-0-12-385114-7.00009-X.

PMID:
21266249
[PubMed - indexed for MEDLINE]
15.
16.

La3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells.

Shen C, Li Z, Yang X, Wang K.

Chem Biol Interact. 2008 Nov 25;176(2-3):196-203. doi: 10.1016/j.cbi.2008.07.014. Epub 2008 Aug 19.

PMID:
18773883
[PubMed - indexed for MEDLINE]
17.

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response.

Tardif KD, Mori K, Kaufman RJ, Siddiqui A.

J Biol Chem. 2004 Apr 23;279(17):17158-64. Epub 2004 Feb 11.

PMID:
14960590
[PubMed - indexed for MEDLINE]
Free Article
18.

Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins.

Kimata Y, Ishiwata-Kimata Y, Ito T, Hirata A, Suzuki T, Oikawa D, Takeuchi M, Kohno K.

J Cell Biol. 2007 Oct 8;179(1):75-86.

PMID:
17923530
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Principles of IRE1 modulation using chemical tools.

Lee KP, Sicheri F.

Methods Enzymol. 2011;490:271-94. doi: 10.1016/B978-0-12-385114-7.00016-7.

PMID:
21266256
[PubMed - indexed for MEDLINE]
20.

IRE1 and efferent signaling from the endoplasmic reticulum.

Urano F, Bertolotti A, Ron D.

J Cell Sci. 2000 Nov;113 Pt 21:3697-702. Review.

PMID:
11034898
[PubMed - indexed for MEDLINE]
Free Article

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