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Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections.

Li JF, Lipscomb JT, Wei X, Martinson NA, Morris L, Heneine W, Johnson JA.

J Infect Dis. 2011 Mar 15;203(6):798-802. doi: 10.1093/infdis/jiq126. Epub 2011 Jan 21.


Polymorphisms and drug resistance analysis of HIV-1 CRF01_AE strains circulating in Fujian Province, China.

Liu J, Yue J, Wu S, Yan Y.

Arch Virol. 2007;152(10):1799-805. Epub 2007 Jul 6.


Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel.

Turner D, Shahar E, Katchman E, Kedem E, Matus N, Katzir M, Hassoun G, Pollack S, Kessner R, Wainberg MA, Avidor B.

J Med Virol. 2009 Sep;81(9):1509-12. doi: 10.1002/jmv.21567.


Prevalence of low-level HIV-1 variants with reverse transcriptase mutation K65R and the effect of antiretroviral drug exposure on variant levels.

Kozal MJ, Chiarella J, St John EP, Moreno EA, Simen BB, Arnold TE, Lataillade M.

Antivir Ther. 2011;16(6):925-9. doi: 10.3851/IMP1851.


HIV-1 subtype is an independent predictor of reverse transcriptase mutation K65R in HIV-1 patients treated with combination antiretroviral therapy including tenofovir.

Theys K, Vercauteren J, Snoeck J, Zazzi M, Camacho RJ, Torti C, Schülter E, Clotet B, Sönnerborg A, De Luca A, Grossman Z, Struck D, Vandamme AM, Abecasis AB.

Antimicrob Agents Chemother. 2013 Feb;57(2):1053-6. doi: 10.1128/AAC.01668-12. Epub 2012 Nov 26.


HIV type 1 pol gene diversity and archived nevirapine resistance mutation in pregnant women in Rwanda.

Servais J, Lambert C, Karita E, Vanhove D, Fischer A, Baurith T, Schmit JC, Schneider F, Hemmer R, Arendt V.

AIDS Res Hum Retroviruses. 2004 Mar;20(3):279-83.


Nucleoside reverse transcriptase inhibitor resistance mutations in subtype F1 strains isolated from heavily treated adolescents in Romania.

Paraschiv S, Otelea D, Baicus C, Tinischi M, Costache M, Neaga E.

Int J Infect Dis. 2009 Jan;13(1):81-9. doi: 10.1016/j.ijid.2008.03.032. Epub 2008 Jul 15.


New trends of primary drug resistance among HIV type 1-infected men who have sex with men in Liaoning Province, China.

Zhao B, Han X, Dai D, Liu J, Ding H, Xu J, Chu Z, Bice T, Diao Y, Shang H.

AIDS Res Hum Retroviruses. 2011 Oct;27(10):1047-53. doi: 10.1089/AID.2010.0119. Epub 2011 May 6.


Resistance-associated mutations after initial antiretroviral treatment failure in a large cohort of patients infected with HIV-1 subtype CRF01_AE.

Praparattanapan J, Kotarathitithum W, Chaiwarith R, Nuntachit N, Sirisanthana T, Supparatpinyo K.

Curr HIV Res. 2012 Dec;10(8):647-52.


Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients.

Vergne L, Peeters M, Mpoudi-Ngole E, Bourgeois A, Liegeois F, Toure-Kane C, Mboup S, Mulanga-Kabeya C, Saman E, Jourdan J, Reynes J, Delaporte E.

J Clin Microbiol. 2000 Nov;38(11):3919-25.


Antiretroviral resistance patterns and HIV-1 subtype in mother-infant pairs after the administration of combination short-course zidovudine plus single-dose nevirapine for the prevention of mother-to-child transmission of HIV.

Chalermchockcharoenkit A, Culnane M, Chotpitayasunondh T, Vanprapa N, Leelawiwat W, Mock PA, Asavapiriyanont S, Teeraratkul A, McConnell MS, McNicholl JM, Tappero JW.

Clin Infect Dis. 2009 Jul 15;49(2):299-305. doi: 10.1086/599612.


Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1.

Coutsinos D, Invernizzi CF, Xu H, Brenner BG, Wainberg MA.

Antivir Chem Chemother. 2010 Jan 5;20(3):117-31. doi: 10.3851/IMP1443.


HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy.

Pillay V, Pillay C, Kantor R, Venter F, Levin L, Morris L.

AIDS Res Hum Retroviruses. 2008 Nov;24(11):1449-54. doi: 10.1089/aid.2008.0180.


Impact of CRF01_AE-specific polymorphic mutations G335D and A371V in the connection subdomain of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on susceptibility to nucleoside RT inhibitors.

Tanuma J, Hachiya A, Ishigaki K, Gatanaga H, Lien TT, Hien ND, Kinh NV, Kaku M, Oka S.

Microbes Infect. 2010 Dec;12(14-15):1170-7. doi: 10.1016/j.micinf.2010.08.003. Epub 2010 Aug 14.


Transmission of human immunodeficiency virus type 1 nevirapine resistance mutation K103N from a treatment-naive mother to her child.

Schmitz T, Kleinkauf N, Klempa B, Ringe H, Varnholt V, Grosch-Wörner I.

Pediatr Infect Dis J. 2006 Mar;25(3):275-6.


K65R in subtype C HIV-1 isolates from patients failing on a first-line regimen including d4T or AZT: comparison of Sanger and UDP sequencing data.

Recordon-Pinson P, Papuchon J, Reigadas S, Deshpande A, Fleury H.

PLoS One. 2012;7(5):e36549. doi: 10.1371/journal.pone.0036549. Epub 2012 May 16.


High rate multiple drug resistances in HIV-infected patients failing nonnucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant.

Chetchotisakd P, Anunnatsiri S, Kiertiburanakul S, Sutthent R, Anekthananon T, Bowonwatanuwong C, Kowadisaiburana B, Supparatpinyo K, Horsakulthai M, Chasombat S, Ruxrungtham K; Study Team.

J Int Assoc Physicians AIDS Care (Chic). 2006 Dec;5(4):152-6.


Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.

Sluis-Cremer N, Sheen CW, Zelina S, Torres PS, Parikh UM, Mellors JW.

Antimicrob Agents Chemother. 2007 Jan;51(1):48-53. Epub 2006 Nov 6.


Multi-nucleoside reverse transcriptase inhibitor resistant HIV type-1 in a patient from Sierra Leone failing stavudine, lamivudine and nevirapine.

Hamers RL, Wensing AM, Back NK, Arcilla MS, Frissen JP.

Antivir Ther. 2011;16(1):115-8. doi: 10.3851/IMP1683.

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