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Results: 1 to 20 of 127

1.

Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain.

Wang H, Xu H, Wu LJ, Kim SS, Chen T, Koga K, Descalzi G, Gong B, Vadakkan KI, Zhang X, Kaang BK, Zhuo M.

Sci Transl Med. 2011 Jan 12;3(65):65ra3. doi: 10.1126/scitranslmed.3001269.

PMID:
21228397
[PubMed - indexed for MEDLINE]
Free Article
2.

Targeting neuronal adenylyl cyclase for the treatment of chronic pain.

Zhuo M.

Drug Discov Today. 2012 Jun;17(11-12):573-82. doi: 10.1016/j.drudis.2012.01.009. Epub 2012 Jan 26. Review.

PMID:
22405897
[PubMed - indexed for MEDLINE]
3.

Targeting pain where it resides ... In the brain.

Sharif-Naeini R, Basbaum AI.

Sci Transl Med. 2011 Jan 12;3(65):65ps1. doi: 10.1126/scitranslmed.3002077.

PMID:
21228395
[PubMed - indexed for MEDLINE]
4.

Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain.

Qu XX, Cai J, Li MJ, Chi YN, Liao FF, Liu FY, Wan Y, Han JS, Xing GG.

Exp Neurol. 2009 Feb;215(2):298-307. doi: 10.1016/j.expneurol.2008.10.018. Epub 2008 Nov 12.

PMID:
19046970
[PubMed - indexed for MEDLINE]
5.

Characterization of chronic constriction of the saphenous nerve, a model of neuropathic pain in mice showing rapid molecular and electrophysiological changes.

Walczak JS, Pichette V, Leblond F, Desbiens K, Beaulieu P.

J Neurosci Res. 2006 May 15;83(7):1310-22.

PMID:
16511871
[PubMed - indexed for MEDLINE]
6.

Elucidation of pathophysiology and treatment of neuropathic pain.

Vranken JH.

Cent Nerv Syst Agents Med Chem. 2012 Dec;12(4):304-14. Review.

PMID:
23033930
[PubMed - indexed for MEDLINE]
7.

Edaravone, a free radical scavenger, is effective on neuropathic pain in rats.

Mao YF, Yan N, Xu H, Sun JH, Xiong YC, Deng XM.

Brain Res. 2009 Jan 12;1248:68-75. doi: 10.1016/j.brainres.2008.10.073. Epub 2008 Nov 11.

PMID:
19028459
[PubMed - indexed for MEDLINE]
8.

Divergent peripheral effects of pituitary adenylate cyclase-activating polypeptide-38 on nociception in rats and mice.

Sándor K, Bölcskei K, McDougall JJ, Schuelert N, Reglodi D, Elekes K, Petho G, Pintér E, Szolcsányi J, Helyes Z.

Pain. 2009 Jan;141(1-2):143-50. doi: 10.1016/j.pain.2008.10.028. Epub 2008 Dec 16.

PMID:
19091468
[PubMed - indexed for MEDLINE]
9.

Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats.

Tegeder I, Niederberger E, Schmidt R, Kunz S, Gühring H, Ritzeler O, Michaelis M, Geisslinger G.

J Neurosci. 2004 Feb 18;24(7):1637-45.

PMID:
14973242
[PubMed - indexed for MEDLINE]
Free Article
10.

Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.

Li XY, Ko HG, Chen T, Descalzi G, Koga K, Wang H, Kim SS, Shang Y, Kwak C, Park SW, Shim J, Lee K, Collingridge GL, Kaang BK, Zhuo M.

Science. 2010 Dec 3;330(6009):1400-4. doi: 10.1126/science.1191792.

PMID:
21127255
[PubMed - indexed for MEDLINE]
Free Article
11.

A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.

Kunori S, Matsumura S, Okuda-Ashitaka E, Katano T, Audoly LP, Urade Y, Ito S.

Glia. 2011 Feb;59(2):208-18. doi: 10.1002/glia.21090.

PMID:
21125641
[PubMed - indexed for MEDLINE]
12.

Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain.

Xing GG, Liu FY, Qu XX, Han JS, Wan Y.

Exp Neurol. 2007 Dec;208(2):323-32. Epub 2007 Sep 12. Erratum in: Exp Neurol. 2008 Apr;210(2):797.

PMID:
17936754
[PubMed - indexed for MEDLINE]
13.

[Contribution of primary sensory neurons and spinal glial cells to pathomechanisms of neuropathic pain].

Obata K, Noguchi K.

Brain Nerve. 2008 May;60(5):483-92. Review. Japanese.

PMID:
18516970
[PubMed - indexed for MEDLINE]
14.

Uncovering new pharmacological targets to treat neuropathic pain by understanding how the organism reacts to nerve injury.

Martin YB, Herradón G, Ezquerra L.

Curr Pharm Des. 2011;17(5):434-48. Review.

PMID:
21375486
[PubMed - indexed for MEDLINE]
15.

Mechanisms and treatment of neuropathic pain.

Vranken JH.

Cent Nerv Syst Agents Med Chem. 2009 Mar;9(1):71-8.

PMID:
20021340
[PubMed - indexed for MEDLINE]
16.

Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation.

Geng SJ, Liao FF, Dang WH, Ding X, Liu XD, Cai J, Han JS, Wan Y, Xing GG.

Exp Neurol. 2010 Apr;222(2):256-66. doi: 10.1016/j.expneurol.2010.01.003. Epub 2010 Jan 14.

PMID:
20079352
[PubMed - indexed for MEDLINE]
17.

Newer N-phthaloyl GABA derivatives with antiallodynic and antihyperalgesic activities in both sciatic nerve and spinal nerve ligation models of neuropathic pain.

Yogeeswari P, Ragavendran JV, Sriram D, Kavya R, Vanitha K, Neelakantan H.

Pharmacology. 2008;81(1):21-31. Epub 2007 Aug 30.

PMID:
17785996
[PubMed - indexed for MEDLINE]
18.

Neuropathic pain: models and mechanisms.

Jarvis MF, Boyce-Rustay JM.

Curr Pharm Des. 2009;15(15):1711-6. Review.

PMID:
19442185
[PubMed - indexed for MEDLINE]
19.

Design and assessment of a potent sodium channel blocking derivative of mexiletine for minimizing experimental neuropathic pain in several rat models.

Weston RM, Subasinghe KR, Staikopoulos V, Jarrott B.

Neurochem Res. 2009 Oct;34(10):1816-23. doi: 10.1007/s11064-009-0012-y. Epub 2009 Jun 6.

PMID:
19504185
[PubMed - indexed for MEDLINE]
20.

Neuropathic pain and reactive gliosis are reversed by dialdehydic compound in neuropathic pain rat models.

Bianco MR, Cirillo G, Petrosino V, Marcello L, Soleti A, Merizzi G, Cavaliere C, Papa M.

Neurosci Lett. 2012 Nov 14;530(1):85-90. doi: 10.1016/j.neulet.2012.08.088. Epub 2012 Sep 12.

PMID:
22981978
[PubMed - indexed for MEDLINE]

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