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Results: 1 to 20 of 112

1.

CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.

Liu H, Ong SE, Badu-Nkansah K, Schindler J, White FM, Hynes RO.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1379-84. doi: 10.1073/pnas.1017228108. Epub 2011 Jan 10.

PMID:
21220330
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility.

Benes CH, Poulogiannis G, Cantley LC, Soltoff SP.

Oncogene. 2012 Feb 2;31(5):653-63. doi: 10.1038/onc.2011.262. Epub 2011 Jul 4.

PMID:
21725358
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation.

Kollmorgen G, Bossenmaier B, Niederfellner G, Häring HU, Lammers R.

PLoS One. 2012;7(12):e53050. doi: 10.1371/journal.pone.0053050. Epub 2012 Dec 31.

PMID:
23300860
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Suppression of autophagy by CUB domain-containing protein 1 signaling is essential for anchorage-independent survival of lung cancer cells.

Uekita T, Fujii S, Miyazawa Y, Hashiguchi A, Abe H, Sakamoto M, Sakai R.

Cancer Sci. 2013 Jul;104(7):865-70. doi: 10.1111/cas.12154. Epub 2013 Apr 19.

PMID:
23510015
[PubMed - indexed for MEDLINE]
5.

CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma.

Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R.

Mol Cell Biol. 2007 Nov;27(21):7649-60. Epub 2007 Sep 4.

PMID:
17785447
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.

Miyazawa Y, Uekita T, Hiraoka N, Fujii S, Kosuge T, Kanai Y, Nojima Y, Sakai R.

Cancer Res. 2010 Jun 15;70(12):5136-46. doi: 10.1158/0008-5472.CAN-10-0220. Epub 2010 May 25.

PMID:
20501830
[PubMed - indexed for MEDLINE]
Free Article
7.

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients.

Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H, Choo-Wing R, Bellinger G, Tsukazawa KS, Brown V, Signoretti S, Soltoff SP, Cantley LC.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3483-8. doi: 10.1073/pnas.1222435110. Epub 2013 Feb 1.

PMID:
23378636
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734.

Wortmann A, He Y, Christensen ME, Linn M, Lumley JW, Pollock PM, Waterhouse NJ, Hooper JD.

J Biol Chem. 2011 Dec 9;286(49):42303-15. doi: 10.1074/jbc.M111.227462. Epub 2011 Oct 12.

PMID:
21994943
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer.

Park JJ, Jin YB, Lee YJ, Lee JS, Lee YS, Ko YG, Lee M.

BMC Cancer. 2012 Mar 6;12:81. doi: 10.1186/1471-2407-12-81.

PMID:
22390300
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer.

McKinley ET, Liu H, McDonald WH, Luo W, Zhao P, Coffey RJ, Hanks SK, Manning HC.

PLoS One. 2013 Nov 8;8(11):e80207. doi: 10.1371/journal.pone.0080207. eCollection 2013.

PMID:
24260357
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Functional role of cell surface CUB domain-containing protein 1 in tumor cell dissemination.

Deryugina EI, Conn EM, Wortmann A, Partridge JJ, Kupriyanova TA, Ardi VC, Hooper JD, Quigley JP.

Mol Cancer Res. 2009 Aug;7(8):1197-211. doi: 10.1158/1541-7786.MCR-09-0100. Epub 2009 Aug 11.

PMID:
19671673
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo.

Hingorani P, Zhang W, Gorlick R, Kolb EA.

Clin Cancer Res. 2009 May 15;15(10):3416-22. doi: 10.1158/1078-0432.CCR-08-1657. Epub 2009 May 15.

PMID:
19447875
[PubMed - indexed for MEDLINE]
Free Article
13.

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135/CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen.

Hooper JD, Zijlstra A, Aimes RT, Liang H, Claassen GF, Tarin D, Testa JE, Quigley JP.

Oncogene. 2003 Mar 27;22(12):1783-94.

PMID:
12660814
[PubMed - indexed for MEDLINE]
14.

Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1.

Fukuchi K, Steiniger SC, Deryugina E, Liu Y, Lowery CA, Gloeckner C, Zhou B, Kaufmann GF, Quigley JP, Janda KD.

Mol Pharm. 2010 Feb 1;7(1):245-53. doi: 10.1021/mp900236t.

PMID:
19916495
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.

He Y, Wortmann A, Burke LJ, Reid JC, Adams MN, Abdul-Jabbar I, Quigley JP, Leduc R, Kirchhofer D, Hooper JD.

J Biol Chem. 2010 Aug 20;285(34):26162-73. doi: 10.1074/jbc.M109.096453. Epub 2010 Jun 15.

PMID:
20551327
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma.

Uekita T, Tanaka M, Takigahira M, Miyazawa Y, Nakanishi Y, Kanai Y, Yanagihara K, Sakai R.

Am J Pathol. 2008 Jun;172(6):1729-39. doi: 10.2353/ajpath.2008.070981. Epub 2008 May 8.

PMID:
18467693
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy.

Kollmorgen G, Niederfellner G, Lifke A, Spohn GJ, Rieder N, Harring SV, Bauss F, Burtscher H, Lammers R, Bossenmaier B.

Mol Oncol. 2013 Dec;7(6):1142-51. doi: 10.1016/j.molonc.2013.08.009. Epub 2013 Sep 3.

PMID:
24055141
[PubMed - indexed for MEDLINE]
Free Article
18.

Effect of the tyrosine kinase inhibitor lapatinib on CUB-domain containing protein (CDCP1)-mediated breast cancer cell survival and migration.

Seidel J, Kunc K, Possinger K, Jehn C, Lüftner D.

Biochem Biophys Res Commun. 2011 Oct 14;414(1):226-32. doi: 10.1016/j.bbrc.2011.09.062. Epub 2011 Sep 17.

PMID:
21945930
[PubMed - indexed for MEDLINE]
19.

The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration.

Dong Y, He Y, de Boer L, Stack MS, Lumley JW, Clements JA, Hooper JD.

J Biol Chem. 2012 Mar 23;287(13):9792-803. doi: 10.1074/jbc.M111.335448. Epub 2012 Feb 7.

PMID:
22315226
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.

Trimmer C, Whitaker-Menezes D, Bonuccelli G, Milliman JN, Daumer KM, Aplin AE, Pestell RG, Sotgia F, Lisanti MP, Capozza F.

Cancer Res. 2010 Oct 1;70(19):7489-99. doi: 10.1158/0008-5472.CAN-10-0900. Epub 2010 Aug 13.

PMID:
20709760
[PubMed - indexed for MEDLINE]
Free PMC Article
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