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Results: 1 to 20 of 98

1.

Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.

Copsel S, Garcia C, Diez F, Vermeulem M, Baldi A, Bianciotti LG, Russel FG, Shayo C, Davio C.

J Biol Chem. 2011 Mar 4;286(9):6979-88. doi: 10.1074/jbc.M110.166868. Epub 2011 Jan 4.

PMID:
21205825
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure.

Pattabiraman PP, Pecen PE, Rao PV.

Invest Ophthalmol Vis Sci. 2013 Mar 5;54(3):1636-49. doi: 10.1167/iovs.12-11107.

PMID:
23385799
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid.

Kim HS, Min YD, Choi CH.

Biochem Biophys Res Commun. 2001 Apr 27;283(1):64-71.

PMID:
11322768
[PubMed - indexed for MEDLINE]
4.

Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation.

Sassi Y, Lipskaia L, Vandecasteele G, Nikolaev VO, Hatem SN, Cohen Aubart F, Russel FG, Mougenot N, Vrignaud C, Lechat P, Lompré AM, Hulot JS.

J Clin Invest. 2008 Aug;118(8):2747-57. doi: 10.1172/JCI35067.

PMID:
18636120
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response.

Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC.

Mol Pharmacol. 2008 Jan;73(1):243-51. Epub 2007 Oct 24.

PMID:
17959714
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Multi-drug resistance protein 4 (MRP4)-mediated regulation of fibroblast cell migration reflects a dichotomous role of intracellular cyclic nucleotides.

Sinha C, Ren A, Arora K, Moon CS, Yarlagadda S, Zhang W, Cheepala SB, Schuetz JD, Naren AP.

J Biol Chem. 2013 Feb 8;288(6):3786-94. doi: 10.1074/jbc.M112.435925. Epub 2012 Dec 21.

PMID:
23264633
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity.

Torphy TJ, Zhou HL, Cieslinski LB.

J Pharmacol Exp Ther. 1992 Dec;263(3):1195-205.

PMID:
1335058
[PubMed - indexed for MEDLINE]
8.

The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.

Shayo C, Legnazzi BL, Monczor F, Fernández N, Riveiro ME, Baldi A, Davio C.

Biochem Biophys Res Commun. 2004 Feb 13;314(3):798-804.

PMID:
14741706
[PubMed - indexed for MEDLINE]
9.

The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

van Aubel RA, Smeets PH, Peters JG, Bindels RJ, Russel FG.

J Am Soc Nephrol. 2002 Mar;13(3):595-603.

PMID:
11856762
[PubMed - indexed for MEDLINE]
Free Article
10.

Cyclic AMP efflux, via MRPs and A1 adenosine receptors, is critical for bovine sperm capacitation.

Osycka-Salut C, Diez F, Burdet J, Gervasi MG, Franchi A, Bianciotti LG, Davio C, Perez-Martinez S.

Mol Hum Reprod. 2014 Jan;20(1):89-99. doi: 10.1093/molehr/gat053. Epub 2013 Aug 1.

PMID:
23907162
[PubMed - in process]
11.

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

Wielinga PR, van der Heijden I, Reid G, Beijnen JH, Wijnholds J, Borst P.

J Biol Chem. 2003 May 16;278(20):17664-71. Epub 2003 Mar 13.

PMID:
12637526
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP.

Xie M, Rich TC, Scheitrum C, Conti M, Richter W.

Mol Pharmacol. 2011 Aug;80(2):281-93. doi: 10.1124/mol.111.071134. Epub 2011 May 6.

PMID:
21551375
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signaling.

Xin W, Tran TM, Richter W, Clark RB, Rich TC.

J Gen Physiol. 2008 Apr;131(4):349-64. doi: 10.1085/jgp.200709881. Epub 2008 Mar 17.

PMID:
18347080
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.

Smeets PH, van Aubel RA, Wouterse AC, van den Heuvel JJ, Russel FG.

J Am Soc Nephrol. 2004 Nov;15(11):2828-35.

PMID:
15504935
[PubMed - indexed for MEDLINE]
Free Article
17.

Histamine up-regulates phosphodiesterase IV activity in U-937 cells through H2 receptor stimulation and cAMP increase.

Delgado M, Fuentes JA, Fernandez-Alfonso MS.

Med Sci Monit. 2003 Jun;9(6):BR212-9.

PMID:
12824943
[PubMed - indexed for MEDLINE]
18.

Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.

Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD.

J Biol Chem. 2012 Apr 27;287(18):14456-66. doi: 10.1074/jbc.M111.319681. Epub 2012 Feb 28.

PMID:
22375007
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of MRP4 prevents and reverses pulmonary hypertension in mice.

Hara Y, Sassi Y, Guibert C, Gambaryan N, Dorfmüller P, Eddahibi S, Lompré AM, Humbert M, Hulot JS.

J Clin Invest. 2011 Jul;121(7):2888-97. doi: 10.1172/JCI45023. Epub 2011 Jun 13.

PMID:
21670499
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells.

Campos-Toimil M, Keravis T, Orallo F, Takeda K, Lugnier C.

Br J Pharmacol. 2008 May;154(1):82-92. doi: 10.1038/bjp.2008.56. Epub 2008 Mar 3.

PMID:
18311187
[PubMed - indexed for MEDLINE]
Free PMC Article

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