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Items: 1 to 20 of 113

1.

Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

Rosowski EE, Lu D, Julien L, Rodda L, Gaiser RA, Jensen KD, Saeij JP.

J Exp Med. 2011 Jan 17;208(1):195-212. doi: 10.1084/jem.20100717. Epub 2011 Jan 3.

2.

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

Jensen KD, Hu K, Whitmarsh RJ, Hassan MA, Julien L, Lu D, Chen L, Hunter CA, Saeij JP.

Infect Immun. 2013 Jun;81(6):2156-67. doi: 10.1128/IAI.01185-12. Epub 2013 Apr 1.

3.

Toxoplasma gondii virulence factor ROP18 inhibits the host NF-κB pathway by promoting p65 degradation.

Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J.

J Biol Chem. 2014 May 2;289(18):12578-92. doi: 10.1074/jbc.M113.544718. Epub 2014 Mar 19.

4.

Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.

Gov L, Karimzadeh A, Ueno N, Lodoen MB.

MBio. 2013 Jul 9;4(4). pii: e00255-13. doi: 10.1128/mBio.00255-13.

5.

Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains.

Yang N, Farrell A, Niedelman W, Melo M, Lu D, Julien L, Marth GT, Gubbels MJ, Saeij JP.

BMC Genomics. 2013 Jul 10;14:467. doi: 10.1186/1471-2164-14-467.

8.

Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile.

Walzer KA, Wier GM, Dam RA, Srinivasan AR, Borges AL, English ED, Herrmann DC, Schares G, Dubey JP, Boyle JP.

Eukaryot Cell. 2014 Dec;13(12):1507-18. doi: 10.1128/EC.00215-14. Epub 2014 Oct 3.

9.

Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses.

Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB.

Infect Immun. 2014 Oct;82(10):4047-55. doi: 10.1128/IAI.01615-14. Epub 2014 Jul 14.

10.

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

Jensen KD, Wang Y, Wojno ED, Shastri AJ, Hu K, Cornel L, Boedec E, Ong YC, Chien YH, Hunter CA, Boothroyd JC, Saeij JP.

Cell Host Microbe. 2011 Jun 16;9(6):472-83. doi: 10.1016/j.chom.2011.04.015.

11.

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

Butcher BA, Fox BA, Rommereim LM, Kim SG, Maurer KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denkers EY.

PLoS Pathog. 2011 Sep;7(9):e1002236. doi: 10.1371/journal.ppat.1002236. Epub 2011 Sep 8.

12.

Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii.

Caamaño J, Tato C, Cai G, Villegas EN, Speirs K, Craig L, Alexander J, Hunter CA.

J Immunol. 2000 Nov 15;165(10):5720-8.

13.

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it.

Virreira Winter S, Niedelman W, Jensen KD, Rosowski EE, Julien L, Spooner E, Caradonna K, Burleigh BA, Saeij JP, Ploegh HL, Frickel EM.

PLoS One. 2011;6(9):e24434. doi: 10.1371/journal.pone.0024434. Epub 2011 Sep 8.

14.

Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.

Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M.

J Exp Med. 2014 Sep 22;211(10):2013-32. doi: 10.1084/jem.20131272. Epub 2014 Sep 15.

15.

Suppression of NF-kappaB activation by infection with Toxoplasma gondii.

Shapira S, Speirs K, Gerstein A, Caamano J, Hunter CA.

J Infect Dis. 2002 Feb 15;185 Suppl 1:S66-72.

16.

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype.

Robben PM, Mordue DG, Truscott SM, Takeda K, Akira S, Sibley LD.

J Immunol. 2004 Mar 15;172(6):3686-94.

17.

Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii.

Shapira S, Harb OS, Margarit J, Matrajt M, Han J, Hoffmann A, Freedman B, May MJ, Roos DS, Hunter CA.

J Cell Sci. 2005 Aug 1;118(Pt 15):3501-8.

19.

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

Yamamoto M, Standley DM, Takashima S, Saiga H, Okuyama M, Kayama H, Kubo E, Ito H, Takaura M, Matsuda T, Soldati-Favre D, Takeda K.

J Exp Med. 2009 Nov 23;206(12):2747-60. doi: 10.1084/jem.20091703. Epub 2009 Nov 9.

20.
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