Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

Trk retrograde signaling requires persistent, Pincher-directed endosomes.

Philippidou P, Valdez G, Akmentin W, Bowers WJ, Federoff HJ, Halegoua S.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):852-7. doi: 10.1073/pnas.1015981108. Epub 2010 Dec 27.

2.

Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors.

Valdez G, Akmentin W, Philippidou P, Kuruvilla R, Ginty DD, Halegoua S.

J Neurosci. 2005 May 25;25(21):5236-47.

3.

Trk-signaling endosomes are generated by Rac-dependent macroendocytosis.

Valdez G, Philippidou P, Rosenbaum J, Akmentin W, Shao Y, Halegoua S.

Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12270-5. Epub 2007 Jul 17.

4.

Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome.

Bronfman FC, Tcherpakov M, Jovin TM, Fainzilber M.

J Neurosci. 2003 Apr 15;23(8):3209-20.

5.

Retrograde neurotrophic signaling requires a protein interacting with receptor tyrosine kinases via C2H2 zinc fingers.

Fu X, Zang K, Zhou Z, Reichardt LF, Xu B.

Mol Biol Cell. 2010 Jan 1;21(1):36-49. doi: 10.1091/mbc.E09-04-0321. Epub 2009 Oct 28.

6.

Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.

Winckler B, Yap CC.

Traffic. 2011 Sep;12(9):1099-108. doi: 10.1111/j.1600-0854.2011.01213.x. Epub 2011 May 23. Review.

7.

Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes.

Shao Y, Akmentin W, Toledo-Aral JJ, Rosenbaum J, Valdez G, Cabot JB, Hilbush BS, Halegoua S.

J Cell Biol. 2002 May 13;157(4):679-91. Epub 2002 May 13.

8.

Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling.

Joset A, Dodd DA, Halegoua S, Schwab ME.

J Cell Biol. 2010 Jan 25;188(2):271-85. doi: 10.1083/jcb.200906089. Epub 2010 Jan 18.

9.

Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival.

Harrington AW, St Hillaire C, Zweifel LS, Glebova NO, Philippidou P, Halegoua S, Ginty DD.

Cell. 2011 Aug 5;146(3):421-34. doi: 10.1016/j.cell.2011.07.008.

10.

Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport.

Mitchell DJ, Blasier KR, Jeffery ED, Ross MW, Pullikuth AK, Suo D, Park J, Smiley WR, Lo KW, Shabanowitz J, Deppmann CD, Trinidad JC, Hunt DF, Catling AD, Pfister KK.

J Neurosci. 2012 Oct 31;32(44):15495-510. doi: 10.1523/JNEUROSCI.5599-11.2012.

11.

Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex.

Watson FL, Heerssen HM, Moheban DB, Lin MZ, Sauvageot CM, Bhattacharyya A, Pomeroy SL, Segal RA.

J Neurosci. 1999 Sep 15;19(18):7889-900.

12.

On Trk for retrograde signaling.

Miller FD, Kaplan DR.

Neuron. 2001 Dec 6;32(5):767-70. Review.

13.

Trafficking the NGF signal: implications for normal and degenerating neurons.

Delcroix JD, Valletta J, Wu C, Howe CL, Lai CF, Cooper JD, Belichenko PV, Salehi A, Mobley WC.

Prog Brain Res. 2004;146:3-23.

PMID:
14699953
14.

Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes.

Grimes ML, Zhou J, Beattie EC, Yuen EC, Hall DE, Valletta JS, Topp KS, LaVail JH, Bunnett NW, Mobley WC.

J Neurosci. 1996 Dec 15;16(24):7950-64.

15.

Axonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responses.

AscaƱo M, Richmond A, Borden P, Kuruvilla R.

J Neurosci. 2009 Sep 16;29(37):11674-85. doi: 10.1523/JNEUROSCI.1542-09.2009.

16.

Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons.

Ye H, Kuruvilla R, Zweifel LS, Ginty DD.

Neuron. 2003 Jul 3;39(1):57-68.

17.

Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth.

Hisata S, Sakisaka T, Baba T, Yamada T, Aoki K, Matsuda M, Takai Y.

J Cell Biol. 2007 Aug 27;178(5):843-60.

18.

GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling.

Varsano T, Dong MQ, Niesman I, Gacula H, Lou X, Ma T, Testa JR, Yates JR 3rd, Farquhar MG.

Mol Cell Biol. 2006 Dec;26(23):8942-52. Epub 2006 Oct 2.

19.

The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling.

Ceni C, Kommaddi RP, Thomas R, Vereker E, Liu X, McPherson PS, Ritter B, Barker PA.

J Cell Sci. 2010 Jul 1;123(Pt 13):2299-307. doi: 10.1242/jcs.062612. Epub 2010 Jun 8.

20.

TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain.

Urra S, Escudero CA, Ramos P, Lisbona F, Allende E, Covarrubias P, Parraguez JI, Zampieri N, Chao MV, Annaert W, Bronfman FC.

J Biol Chem. 2007 Mar 9;282(10):7606-15. Epub 2007 Jan 9.

Items per page

Supplemental Content

Write to the Help Desk