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Results: 1 to 20 of 204

1.

Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system.

Anantharaman V, Abhiman S, de Souza RF, Aravind L.

Gene. 2011 Apr 15;475(2):63-78. doi: 10.1016/j.gene.2010.12.001. Epub 2010 Dec 20.

PMID:
21182906
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

Siderovski DP, Willard FS.

Int J Biol Sci. 2005;1(2):51-66. Epub 2005 Apr 1. Review.

PMID:
15951850
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

G protein activation without a GEF in the plant kingdom.

Urano D, Jones JC, Wang H, Matthews M, Bradford W, Bennetzen JL, Jones AM.

PLoS Genet. 2012 Jun;8(6):e1002756. doi: 10.1371/journal.pgen.1002756. Epub 2012 Jun 28.

PMID:
22761582
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Interactions of the α-subunits of heterotrimeric G-proteins with GPCRs, effectors and RGS proteins: a critical review and analysis of interacting surfaces, conformational shifts, structural diversity and electrostatic potentials.

Baltoumas FA, Theodoropoulou MC, Hamodrakas SJ.

J Struct Biol. 2013 Jun;182(3):209-18. doi: 10.1016/j.jsb.2013.03.004. Epub 2013 Mar 21.

PMID:
23523730
[PubMed - indexed for MEDLINE]
5.

Fluorescence-based assays for RGS box function.

Willard FS, Kimple RJ, Kimple AJ, Johnston CA, Siderovski DP.

Methods Enzymol. 2004;389:56-71. Review.

PMID:
15313559
[PubMed - indexed for MEDLINE]
6.

Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.

Kimple AJ, Bosch DE, Giguère PM, Siderovski DP.

Pharmacol Rev. 2011 Sep;63(3):728-49. doi: 10.1124/pr.110.003038. Epub 2011 Jul 7. Review.

PMID:
21737532
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The RGS proteins add to the diversity of soybean heterotrimeric G-protein signaling.

Choudhury SR, Westfall CS, Pandey S.

Plant Signal Behav. 2012 Sep 1;7(9):1114-7. doi: 10.4161/psb.21298. Epub 2012 Aug 17.

PMID:
22899066
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cells.

Witherow DS, Wang Q, Levay K, Cabrera JL, Chen J, Willars GB, Slepak VZ.

J Biol Chem. 2000 Aug 11;275(32):24872-80.

PMID:
10840031
[PubMed - indexed for MEDLINE]
Free Article
9.

Two RGS proteins that inhibit Galpha(o) and Galpha(q) signaling in C. elegans neurons require a Gbeta(5)-like subunit for function.

Chase DL, Patikoglou GA, Koelle MR.

Curr Biol. 2001 Feb 20;11(4):222-31.

PMID:
11250150
[PubMed - indexed for MEDLINE]
Free Article
10.

Measurement of GTP-binding and GTPase activity of heterotrimeric Gα proteins.

Choudhury SR, Westfall CS, Hackenberg D, Pandey S.

Methods Mol Biol. 2013;1043:13-20. doi: 10.1007/978-1-62703-532-3_2.

PMID:
23913031
[PubMed - indexed for MEDLINE]
11.

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.

Soundararajan M, Willard FS, Kimple AJ, Turnbull AP, Ball LJ, Schoch GA, Gileadi C, Fedorov OY, Dowler EF, Higman VA, Hutsell SQ, Sundström M, Doyle DA, Siderovski DP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6457-62. doi: 10.1073/pnas.0801508105. Epub 2008 Apr 23.

PMID:
18434541
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao.

Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD.

Biochem J. 2000 Aug 15;350 Pt 1:19-29.

PMID:
10926822
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Characterization of a novel C. elegans RGS protein with a C2 domain: evidence for direct association between C2 domain and Galphaq subunit.

Sato M, Moroi K, Nishiyama M, Zhou J, Usui H, Kasuya Y, Fukuda M, Kohara Y, Komuro I, Kimura S.

Life Sci. 2003 Jul 4;73(7):917-32.

PMID:
12798417
[PubMed - indexed for MEDLINE]
14.

Structural determinants of G-protein alpha subunit selectivity by regulator of G-protein signaling 2 (RGS2).

Kimple AJ, Soundararajan M, Hutsell SQ, Roos AK, Urban DJ, Setola V, Temple BR, Roth BL, Knapp S, Willard FS, Siderovski DP.

J Biol Chem. 2009 Jul 17;284(29):19402-11. doi: 10.1074/jbc.M109.024711. Epub 2009 May 28.

PMID:
19478087
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins.

Ross EM, Wilkie TM.

Annu Rev Biochem. 2000;69:795-827. Review.

PMID:
10966476
[PubMed - indexed for MEDLINE]
16.

Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.

Clark MJ, Harrison C, Zhong H, Neubig RR, Traynor JR.

J Biol Chem. 2003 Mar 14;278(11):9418-25. Epub 2003 Jan 10.

PMID:
12524446
[PubMed - indexed for MEDLINE]
Free Article
17.

RGS3 is a GTPase-activating protein for g(ialpha) and g(qalpha) and a potent inhibitor of signaling by GTPase-deficient forms of g(qalpha) and g(11alpha).

Scheschonka A, Dessauer CW, Sinnarajah S, Chidiac P, Shi CS, Kehrl JH.

Mol Pharmacol. 2000 Oct;58(4):719-28.

PMID:
10999941
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation.

Shi CS, Lee SB, Sinnarajah S, Dessauer CW, Rhee SG, Kehrl JH.

J Biol Chem. 2001 Jun 29;276(26):24293-300. Epub 2001 Apr 9.

PMID:
11294858
[PubMed - indexed for MEDLINE]
Free Article
19.

Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants.

Chatterjee TK, Liu Z, Fisher RA.

J Biol Chem. 2003 Aug 8;278(32):30261-71. Epub 2003 May 21.

PMID:
12761221
[PubMed - indexed for MEDLINE]
Free Article
20.

RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6.

Liu Z, Chatterjee TK, Fisher RA.

J Biol Chem. 2002 Oct 4;277(40):37832-9. Epub 2002 Jul 24.

PMID:
12140291
[PubMed - indexed for MEDLINE]
Free Article

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