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Items: 1 to 20 of 102


Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.

Ring C, Ginsberg MH, Haling J, Pendergast AM.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):149-54. doi: 10.1073/pnas.1012316108. Epub 2010 Dec 20.


Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

Abou-Kheir W, Isaac B, Yamaguchi H, Cox D.

J Cell Sci. 2008 Feb 1;121(Pt 3):379-90. doi: 10.1242/jcs.010272. Epub 2008 Jan 15.


Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.

Dubielecka PM, Ladwein KI, Xiong X, Migeotte I, Chorzalska A, Anderson KV, Sawicki JA, Rottner K, Stradal TE, Kotula L.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7. doi: 10.1073/pnas.1016811108. Epub 2011 Apr 11.


Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo.

Yu W, Sun X, Clough N, Cobos E, Tao Y, Dai Z.

Carcinogenesis. 2008 Sep;29(9):1717-24. doi: 10.1093/carcin/bgn098. Epub 2008 May 2.


Role of the adapter protein Abi1 in actin-associated signaling and smooth muscle contraction.

Wang T, Cleary RA, Wang R, Tang DD.

J Biol Chem. 2013 Jul 12;288(28):20713-22. doi: 10.1074/jbc.M112.439877. Epub 2013 Jun 5.


The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.

Eto K, Nishikii H, Ogaeri T, Suetsugu S, Kamiya A, Kobayashi T, Yamazaki D, Oda A, Takenawa T, Nakauchi H.

Blood. 2007 Nov 15;110(10):3637-47. Epub 2007 Jul 30.


Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

Innocenti M, Zucconi A, Disanza A, Frittoli E, Areces LB, Steffen A, Stradal TE, Di Fiore PP, Carlier MF, Scita G.

Nat Cell Biol. 2004 Apr;6(4):319-27. Epub 2004 Mar 28.


Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.

Steinestel K, Brüderlein S, Lennerz JK, Steinestel J, Kraft K, Pröpper C, Meineke V, Möller P.

Mol Cancer. 2014 Jun 9;13:145. doi: 10.1186/1476-4598-13-145.


Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration.

Goldfinger LE, Han J, Kiosses WB, Howe AK, Ginsberg MH.

J Cell Biol. 2003 Aug 18;162(4):731-41. Epub 2003 Aug 11.


An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.

Nishiya N, Kiosses WB, Han J, Ginsberg MH.

Nat Cell Biol. 2005 Apr;7(4):343-52. Epub 2005 Mar 27. Erratum in: Nat Cell Biol. 2005 May;7(5):531.


Abelson interactor 1 (ABI1) and its interaction with Wiskott-Aldrich syndrome protein (wasp) are critical for proper eye formation in Xenopus embryos.

Singh A, Winterbottom EF, Ji YJ, Hwang YS, Daar IO.

J Biol Chem. 2013 May 17;288(20):14135-46. doi: 10.1074/jbc.M112.445643. Epub 2013 Apr 4.


Differential regulation of cell adhesive functions by integrin alpha subunit cytoplasmic tails in vivo.

Na J, Marsden M, DeSimone DW.

J Cell Sci. 2003 Jun 1;116(Pt 11):2333-43. Epub 2003 Apr 23.


A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages.

Kheir WA, Gevrey JC, Yamaguchi H, Isaac B, Cox D.

J Cell Sci. 2005 Nov 15;118(Pt 22):5369-79.


β8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart.

Jung Y, Kissil JL, McCarty JH.

Dev Dyn. 2011 Jan;240(1):271-7. doi: 10.1002/dvdy.22513.


CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis.

Zhuang C, Tang H, Dissanaike S, Cobos E, Tao Y, Dai Z.

J Biol Chem. 2011 Nov 4;286(44):38614-26. doi: 10.1074/jbc.M111.281139. Epub 2011 Sep 7.


Regulation of cell-cell adhesion by Abi/Diaphanous complexes.

Ryu JR, Echarri A, Li R, Pendergast AM.

Mol Cell Biol. 2009 Apr;29(7):1735-48. doi: 10.1128/MCB.01483-08. Epub 2009 Jan 21.


Association between α4 integrin cytoplasmic tail and non-muscle myosin IIA regulates cell migration.

Rivera Rosado LA, Horn TA, McGrath SC, Cotter RJ, Yang JT.

J Cell Sci. 2011 Feb 1;124(Pt 3):483-92. doi: 10.1242/jcs.074211. Epub 2011 Jan 11.


Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes.

Innocenti M, Gerboth S, Rottner K, Lai FP, Hertzog M, Stradal TE, Frittoli E, Didry D, Polo S, Disanza A, Benesch S, Di Fiore PP, Carlier MF, Scita G.

Nat Cell Biol. 2005 Oct;7(10):969-76. Epub 2005 Sep 11.


Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway.

Li Y, Clough N, Sun X, Yu W, Abbott BL, Hogan CJ, Dai Z.

J Cell Sci. 2007 Apr 15;120(Pt 8):1436-46. Epub 2007 Mar 27.


ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.

Mendoza MC, Er EE, Zhang W, Ballif BA, Elliott HL, Danuser G, Blenis J.

Mol Cell. 2011 Mar 18;41(6):661-71. doi: 10.1016/j.molcel.2011.02.031.

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