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Results: 1 to 20 of 114

1.

New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation.

Jimeno S, Tous C, García-Rubio ML, Ranes M, González-Aguilera C, Marín A, Aguilera A.

Mol Cell Biol. 2011 Feb;31(4):674-85. doi: 10.1128/MCB.01188-10. Epub 2010 Dec 13.

PMID:
21149575
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants.

Jimeno S, Luna R, García-Rubio M, Aguilera A.

Mol Cell Biol. 2006 Jun;26(12):4387-98.

PMID:
16738307
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Insights into mRNP biogenesis provided by new genetic interactions among export and transcription factors.

Estruch F, Hodge C, Gómez-Navarro N, Peiró-Chova L, Heath CV, Cole CN.

BMC Genet. 2012 Sep 10;13:80. doi: 10.1186/1471-2156-13-80.

PMID:
22963203
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.

Huertas P, García-Rubio ML, Wellinger RE, Luna R, Aguilera A.

Mol Cell Biol. 2006 Oct;26(20):7451-65. Epub 2006 Aug 14.

PMID:
16908536
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.

García-Rubio M, Chávez S, Huertas P, Tous C, Jimeno S, Luna R, Aguilera A.

Mol Genet Genomics. 2008 Feb;279(2):123-32. Epub 2007 Oct 25.

PMID:
17960421
[PubMed - indexed for MEDLINE]
6.

Interdependence between transcription and mRNP processing and export, and its impact on genetic stability.

Luna R, Jimeno S, Marín M, Huertas P, García-Rubio M, Aguilera A.

Mol Cell. 2005 Jun 10;18(6):711-22.

PMID:
15949445
[PubMed - indexed for MEDLINE]
Free Article
7.

The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Jimeno S, Rondón AG, Luna R, Aguilera A.

EMBO J. 2002 Jul 1;21(13):3526-35.

PMID:
12093753
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

New clues to understand the role of THO and other functionally related factors in mRNP biogenesis.

Luna R, Rondón AG, Aguilera A.

Biochim Biophys Acta. 2012 Jun;1819(6):514-20. doi: 10.1016/j.bbagrm.2011.11.012. Epub 2011 Dec 20. Review.

PMID:
22207203
[PubMed - indexed for MEDLINE]
Free Article
9.

Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles.

Gómez-González B, García-Rubio M, Bermejo R, Gaillard H, Shirahige K, Marín A, Foiani M, Aguilera A.

EMBO J. 2011 Jun 24;30(15):3106-19. doi: 10.1038/emboj.2011.206.

PMID:
21701562
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.

Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ.

Mol Cell. 2008 Dec 5;32(5):735-46. doi: 10.1016/j.molcel.2008.11.012.

PMID:
19061648
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants.

Jimeno S, García-Rubio M, Luna R, Aguilera A.

Mol Genet Genomics. 2008 Oct;280(4):327-36. doi: 10.1007/s00438-008-0368-8. Epub 2008 Aug 6.

PMID:
18682986
[PubMed - indexed for MEDLINE]
12.

Nap1 links transcription elongation, chromatin assembly, and messenger RNP complex biogenesis.

Del Rosario BC, Pemberton LF.

Mol Cell Biol. 2008 Apr;28(7):2113-24. doi: 10.1128/MCB.02136-07. Epub 2008 Jan 28.

PMID:
18227150
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.

González-Aguilera C, Tous C, Gómez-González B, Huertas P, Luna R, Aguilera A.

Mol Biol Cell. 2008 Oct;19(10):4310-8. doi: 10.1091/mbc.E08-04-0355. Epub 2008 Jul 30.

PMID:
18667528
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Genes with internal repeats require the THO complex for transcription.

Voynov V, Verstrepen KJ, Jansen A, Runner VM, Buratowski S, Fink GR.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14423-8. Epub 2006 Sep 18.

PMID:
16983072
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association.

Rougemaille M, Dieppois G, Kisseleva-Romanova E, Gudipati RK, Lemoine S, Blugeon C, Boulay J, Jensen TH, Stutz F, Devaux F, Libri D.

Cell. 2008 Oct 17;135(2):308-21. doi: 10.1016/j.cell.2008.08.005.

PMID:
18957205
[PubMed - indexed for MEDLINE]
Free Article
16.

Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p.

Yu TY, Wang CY, Lin JJ.

PLoS One. 2012;7(3):e33498. doi: 10.1371/journal.pone.0033498. Epub 2012 Mar 20. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/2e35aeeb-4f49-4957-931f-9d942a856e42.

PMID:
22448247
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor.

Peña A, Gewartowski K, Mroczek S, Cuéllar J, Szykowska A, Prokop A, Czarnocki-Cieciura M, Piwowarski J, Tous C, Aguilera A, Carrascosa JL, Valpuesta JM, Dziembowski A.

EMBO J. 2012 Mar 21;31(6):1605-16. doi: 10.1038/emboj.2012.10. Epub 2012 Feb 7.

PMID:
22314234
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants.

Gómez-González B, Felipe-Abrio I, Aguilera A.

Mol Cell Biol. 2009 Oct;29(19):5203-13. doi: 10.1128/MCB.00402-09. Epub 2009 Aug 3.

PMID:
19651896
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants.

Rougemaille M, Gudipati RK, Olesen JR, Thomsen R, Seraphin B, Libri D, Jensen TH.

EMBO J. 2007 May 2;26(9):2317-26. Epub 2007 Apr 5.

PMID:
17410208
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A genetic screen in Saccharomyces cerevisiae identifies new genes that interact with mex67-5, a temperature-sensitive allele of the gene encoding the mRNA export receptor.

Estruch F, Peiró-Chova L, Gómez-Navarro N, Durbán J, Hodge C, Del Olmo M, Cole CN.

Mol Genet Genomics. 2009 Jan;281(1):125-34. doi: 10.1007/s00438-008-0402-x. Epub 2008 Nov 26.

PMID:
19034519
[PubMed - indexed for MEDLINE]

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