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Results: 1 to 20 of 125

1.

Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.

Krzeminski J, Kropachev K, Kolbanovskiy M, Reeves D, Kolbanovskiy A, Yun BH, Geacintov NE, Amin S, El-Bayoumy K.

Chem Res Toxicol. 2011 Jan 14;24(1):65-72. doi: 10.1021/tx100284h. Epub 2010 Nov 29.

PMID:
21114286
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.

Krzeminski J, Kropachev K, Reeves D, Kolbanovskiy A, Kolbanovskiy M, Chen KM, Sharma AK, Geacintov N, Amin S, El-Bayoumy K.

Chem Res Toxicol. 2013 Nov 18;26(11):1746-54. doi: 10.1021/tx400296x. Epub 2013 Oct 30.

PMID:
24112095
[PubMed - indexed for MEDLINE]
3.

Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.

El-Bayoumy K, Sharma AK, Lin JM, Krzeminski J, Boyiri T, King LC, Lambert G, Padgett W, Nesnow S, Amin S.

Chem Res Toxicol. 2004 Dec;17(12):1591-9.

PMID:
15606134
[PubMed - indexed for MEDLINE]
4.

DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.

Perlow RA, Kolbanovskii A, Hingerty BE, Geacintov NE, Broyde S, Scicchitano DA.

J Mol Biol. 2002 Aug 2;321(1):29-47.

PMID:
12139931
[PubMed - indexed for MEDLINE]
5.

Detection and quantitation of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adducts in DNA using online column-switching liquid chromatography tandem mass spectrometry.

Singh R, Arlt VM, Henderson CJ, Phillips DH, Farmer PB, Gamboa da Costa G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 1;878(23):2155-62. doi: 10.1016/j.jchromb.2010.06.008. Epub 2010 Jun 11.

PMID:
20598652
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.

Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE.

Nucleic Acids Res. 2011 Nov 1;39(20):8752-64. doi: 10.1093/nar/gkr537. Epub 2011 Jul 15.

PMID:
21764772
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland.

El-Bayoumy K, Desai D, Boyiri T, Rosa J, Krzeminski J, Sharma AK, Pittman B, Amin S.

Chem Res Toxicol. 2002 Jul;15(7):972-8.

PMID:
12119009
[PubMed - indexed for MEDLINE]
10.

Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extracts.

Choudhury S, Pan J, Amin S, Chung FL, Roy R.

Biochemistry. 2004 Jun 15;43(23):7514-21.

PMID:
15182193
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.

Dreij K, Seidel A, Jernström B.

Chem Res Toxicol. 2005 Apr;18(4):655-64.

PMID:
15833025
[PubMed - indexed for MEDLINE]
12.

Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.

Matter B, Wang G, Jones R, Tretyakova N.

Chem Res Toxicol. 2004 Jun;17(6):731-41.

PMID:
15206894
[PubMed - indexed for MEDLINE]
13.

Differential incision of bulky carcinogen-DNA adducts by the UvrABC nuclease: comparison of incision rates and the interactions of Uvr subunits with lesions of different structures.

Hoare S, Zou Y, Purohit V, Krishnasamy R, Skorvaga M, Van Houten B, Geacintov NE, Basu AK.

Biochemistry. 2000 Oct 10;39(40):12252-61.

PMID:
11015204
[PubMed - indexed for MEDLINE]
14.

The sequence dependence of human nucleotide excision repair efficiencies of benzo[a]pyrene-derived DNA lesions: insights into the structural factors that favor dual incisions.

Kropachev K, Kolbanovskii M, Cai Y, Rodríguez F, Kolbanovskii A, Liu Y, Zhang L, Amin S, Patel D, Broyde S, Geacintov NE.

J Mol Biol. 2009 Mar 13;386(5):1193-203. doi: 10.1016/j.jmb.2008.12.082. Epub 2009 Jan 8.

PMID:
19162041
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Distant neighbor base sequence context effects in human nucleotide excision repair of a benzo[a]pyrene-derived DNA lesion.

Cai Y, Kropachev K, Xu R, Tang Y, Kolbanovskii M, Kolbanovskii A, Amin S, Patel DJ, Broyde S, Geacintov NE.

J Mol Biol. 2010 Jun 11;399(3):397-409. doi: 10.1016/j.jmb.2010.04.004. Epub 2010 Apr 22.

PMID:
20399214
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Synthesis, characterization, and comparative 32P-postlabeling efficiencies of 2,6-dimethylaniline-DNA adducts.

Gonçalves LL, Beland FA, Marques MM.

Chem Res Toxicol. 2001 Feb;14(2):165-74.

PMID:
11258965
[PubMed - indexed for MEDLINE]
17.

The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions.

Mocquet V, Kropachev K, Kolbanovskiy M, Kolbanovskiy A, Tapias A, Cai Y, Broyde S, Geacintov NE, Egly JM.

EMBO J. 2007 Jun 20;26(12):2923-32. Epub 2007 May 24.

PMID:
17525733
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.

Yasui M, Dong H, Bonala RR, Suzuki N, Ohmori H, Hanaoka F, Johnson F, Grollman AP, Shibutani S.

Biochemistry. 2004 Nov 30;43(47):15005-13.

PMID:
15554708
[PubMed - indexed for MEDLINE]
19.

Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice.

Li EE, Heflich RH, Bucci TJ, Manjanatha MG, Blaydes BS, Delclos KB.

Carcinogenesis. 1994 Jul;15(7):1377-85.

PMID:
8033314
[PubMed - indexed for MEDLINE]
20.

Detection and quantitation of benzo[a]pyrene-derived DNA adducts in mouse liver by liquid chromatography-tandem mass spectrometry: comparison with 32P-postlabeling.

Singh R, Gaskell M, Le Pla RC, Kaur B, Azim-Araghi A, Roach J, Koukouves G, Souliotis VL, Kyrtopoulos SA, Farmer PB.

Chem Res Toxicol. 2006 Jun;19(6):868-78.

PMID:
16780367
[PubMed - indexed for MEDLINE]

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