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Results: 1 to 20 of 98

1.

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.

Nowacek AS, Balkundi S, McMillan J, Roy U, Martinez-Skinner A, Mosley RL, Kanmogne G, Kabanov AV, Bronich T, Gendelman HE.

J Control Release. 2011 Mar 10;150(2):204-11. doi: 10.1016/j.jconrel.2010.11.019. Epub 2010 Nov 23.

PMID:
21108978
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics.

Nowacek AS, McMillan J, Miller R, Anderson A, Rabinow B, Gendelman HE.

J Neuroimmune Pharmacol. 2010 Dec;5(4):592-601. doi: 10.1007/s11481-010-9198-7. Epub 2010 Mar 17.

PMID:
20237859
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery.

Nowacek AS, Miller RL, McMillan J, Kanmogne G, Kanmogne M, Mosley RL, Ma Z, Graham S, Chaubal M, Werling J, Rabinow B, Dou H, Gendelman HE.

Nanomedicine (Lond). 2009 Dec;4(8):903-17. doi: 10.2217/nnm.09.71.

PMID:
19958227
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections.

Puligujja P, McMillan J, Kendrick L, Li T, Balkundi S, Smith N, Veerubhotla RS, Edagwa BJ, Kabanov AV, Bronich T, Gendelman HE, Liu XM.

Nanomedicine. 2013 Nov;9(8):1263-73. doi: 10.1016/j.nano.2013.05.003. Epub 2013 May 13.

PMID:
23680933
[PubMed - indexed for MEDLINE]
5.

Comparative manufacture and cell-based delivery of antiretroviral nanoformulations.

Balkundi S, Nowacek AS, Veerubhotla RS, Chen H, Martinez-Skinner A, Roy U, Mosley RL, Kanmogne G, Liu X, Kabanov AV, Bronich T, McMillan J, Gendelman HE.

Int J Nanomedicine. 2011;6:3393-404. doi: 10.2147/IJN.S27830. Epub 2011 Dec 20.

PMID:
22267924
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells.

Kanmogne GD, Singh S, Roy U, Liu X, McMillan J, Gorantla S, Balkundi S, Smith N, Alnouti Y, Gautam N, Zhou Y, Poluektova L, Kabanov A, Bronich T, Gendelman HE.

Int J Nanomedicine. 2012;7:2373-88. doi: 10.2147/IJN.S29454. Epub 2012 May 8.

PMID:
22661891
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice.

Dash PK, Gendelman HE, Roy U, Balkundi S, Alnouti Y, Mosley RL, Gelbard HA, McMillan J, Gorantla S, Poluektova LY.

AIDS. 2012 Nov 13;26(17):2135-44. doi: 10.1097/QAD.0b013e328357f5ad.

PMID:
22824628
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage.

Bressani RF, Nowacek AS, Singh S, Balkundi S, Rabinow B, McMillan J, Gendelman HE, Kanmogne GD.

Nanotoxicology. 2011 Dec;5(4):592-605. doi: 10.3109/17435390.2010.541292. Epub 2010 Dec 22.

PMID:
21175298
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs.

Balkundi S, Nowacek AS, Roy U, Martinez-Skinner A, McMillan J, Gendelman HE.

J Vis Exp. 2010 Dec 9;(46). pii: 2460. doi: 10.3791/2460.

PMID:
21178968
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacity.

Martinez-Skinner AL, Veerubhotla RS, Liu H, Xiong H, Yu F, McMillan JM, Gendelman HE.

J Proteome Res. 2013 May 3;12(5):2282-94. doi: 10.1021/pr400185w. Epub 2013 Apr 17.

PMID:
23544708
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Macrophage endocytic trafficking of antiretroviral nanoparticles.

Kadiu I, Nowacek A, McMillan J, Gendelman HE.

Nanomedicine (Lond). 2011 Aug;6(6):975-94. doi: 10.2217/nnm.11.27. Epub 2011 Mar 21.

PMID:
21417829
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS.

Dou H, Grotepas CB, McMillan JM, Destache CJ, Chaubal M, Werling J, Kipp J, Rabinow B, Gendelman HE.

J Immunol. 2009 Jul 1;183(1):661-9. doi: 10.4049/jimmunol.0900274. Epub 2009 Jun 17.

PMID:
19535632
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Duration of first-line antiretroviral therapy with tenofovir and emtricitabine combined with atazanavir/ritonavir, efavirenz or lopinavir/ritonavir in the Italian ARCA cohort.

Di Biagio A, Prinapori R, Giannarelli D, Maggiolo F, Di Giambenedetto S, Borghi V, Penco G, Cicconi P, Francisci D, Sterrantino G, Zoncada A, Monno L, Capetti A, Giacometti A; ARCA Collaborative Group.

J Antimicrob Chemother. 2013 Jan;68(1):200-5. doi: 10.1093/jac/dks339. Epub 2012 Aug 21.

PMID:
22915463
[PubMed - indexed for MEDLINE]
Free Article
14.

Efficacy of Tat-conjugated ritonavir-loaded nanoparticles in reducing HIV-1 replication in monocyte-derived macrophages and cytocompatibility with macrophages and human neurons.

Borgmann K, Rao KS, Labhasetwar V, Ghorpade A.

AIDS Res Hum Retroviruses. 2011 Aug;27(8):853-62. doi: 10.1089/AID.2010.0295. Epub 2011 Feb 2.

PMID:
21175357
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy.

Gautam N, Roy U, Balkundi S, Puligujja P, Guo D, Smith N, Liu XM, Lamberty B, Morsey B, Fox HS, McMillan J, Gendelman HE, Alnouti Y.

Antimicrob Agents Chemother. 2013 Jul;57(7):3110-20. doi: 10.1128/AAC.00267-13. Epub 2013 Apr 22.

PMID:
23612193
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Lopinavir/ritonavir: a review of its use in the management of HIV infection.

Cvetkovic RS, Goa KL.

Drugs. 2003;63(8):769-802. Review.

PMID:
12662125
[PubMed - indexed for MEDLINE]
17.

Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages.

Dou H, Morehead J, Destache CJ, Kingsley JD, Shlyakhtenko L, Zhou Y, Chaubal M, Werling J, Kipp J, Rabinow BE, Gendelman HE.

Virology. 2007 Feb 5;358(1):148-58. Epub 2006 Sep 25.

PMID:
16997345
[PubMed - indexed for MEDLINE]
Free Article
18.

UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues.

Huang J, Gautam N, Bathena SP, Roy U, McMillan J, Gendelman HE, Alnouti Y.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 1;879(23):2332-8. doi: 10.1016/j.jchromb.2011.06.032. Epub 2011 Jul 1.

PMID:
21752731
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Unboosted atazanavir-based therapy maintains control of HIV type-1 replication as effectively as a ritonavir-boosted regimen.

Ghosn J, Carosi G, Moreno S, Pokrovsky V, Lazzarin A, Pialoux G, Sanz-Moreno J, Balogh A, Vandeloise E, Biguenet S, Leleu G, Delfraissy JF.

Antivir Ther. 2010;15(7):993-1002. doi: 10.3851/IMP1666.

PMID:
21041914
[PubMed - indexed for MEDLINE]
20.

Endosomal trafficking of nanoformulated antiretroviral therapy facilitates drug particle carriage and HIV clearance.

Guo D, Zhang G, Wysocki TA, Wysocki BJ, Gelbard HA, Liu XM, McMillan JM, Gendelman HE.

J Virol. 2014 Sep 1;88(17):9504-13. doi: 10.1128/JVI.01557-14. Epub 2014 Jun 11.

PMID:
24920821
[PubMed - in process]
Free PMC Article

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