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Results: 1 to 20 of 115

1.

A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress.

Duch A, Palou G, Jonsson ZO, Palou R, Calvo E, Wohlschlegel J, Quintana DG.

J Biol Chem. 2011 Jan 28;286(4):2486-91. doi: 10.1074/jbc.M110.190843. Epub 2010 Nov 23.

PMID:
21098477
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Damage-induced phosphorylation of Sld3 is important to block late origin firing.

Lopez-Mosqueda J, Maas NL, Jonsson ZO, Defazio-Eli LG, Wohlschlegel J, Toczyski DP.

Nature. 2010 Sep 23;467(7314):479-83. doi: 10.1038/nature09377.

PMID:
20865002
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation.

Zegerman P, Diffley JF.

Nature. 2010 Sep 23;467(7314):474-8. doi: 10.1038/nature09373. Epub 2010 Sep 12.

PMID:
20835227
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint.

Ogi H, Wang CZ, Nakai W, Kawasaki Y, Masumoto H.

Gene. 2008 May 15;414(1-2):32-40. doi: 10.1016/j.gene.2008.02.010. Epub 2008 Feb 21.

PMID:
18372119
[PubMed - indexed for MEDLINE]
5.

DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae.

Chen YC, Kenworthy J, Gabrielse C, Hänni C, Zegerman P, Weinreich M.

Genetics. 2013 Jun;194(2):389-401. doi: 10.1534/genetics.113.149740. Epub 2013 Apr 5.

PMID:
23564203
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Molecular basis of the essential s phase function of the rad53 checkpoint kinase.

Hoch NC, Chen ES, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J.

Mol Cell Biol. 2013 Aug;33(16):3202-13. doi: 10.1128/MCB.00474-13. Epub 2013 Jun 10.

PMID:
23754745
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents.

Varrin AE, Prasad AA, Scholz RP, Ramer MD, Duncker BP.

Mol Cell Biol. 2005 Sep;25(17):7494-504.

PMID:
16107698
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Saccharomyces cerevisiae Dbf4 has unique fold necessary for interaction with Rad53 kinase.

Matthews LA, Jones DR, Prasad AA, Duncker BP, Guarné A.

J Biol Chem. 2012 Jan 20;287(4):2378-87. doi: 10.1074/jbc.M111.233973. Epub 2011 Nov 29.

PMID:
22130670
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits.

Ramer MD, Suman ES, Richter H, Stanger K, Spranger M, Bieberstein N, Duncker BP.

J Biol Chem. 2013 May 24;288(21):14926-35. doi: 10.1074/jbc.M112.392910. Epub 2013 Apr 2.

PMID:
23549044
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.

O'Neill BM, Szyjka SJ, Lis ET, Bailey AO, Yates JR 3rd, Aparicio OM, Romesberg FE.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9290-5. Epub 2007 May 21.

PMID:
17517611
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic interaction of RAD53 protein kinase with histones is important for DNA replication.

Holzen TM, Sclafani R.

Cell Cycle. 2010 Dec 1;9(23):4735-47. Epub 2010 Dec 1.

PMID:
21099362
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins.

Matthews LA, Selvaratnam R, Jones DR, Akimoto M, McConkey BJ, Melacini G, Duncker BP, Guarné A.

J Biol Chem. 2014 Jan 31;289(5):2589-99. doi: 10.1074/jbc.M113.517060. Epub 2013 Nov 27.

PMID:
24285546
[PubMed - indexed for MEDLINE]
13.

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression.

Sheu YJ, Kinney JB, Lengronne A, Pasero P, Stillman B.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1899-908. doi: 10.1073/pnas.1404063111. Epub 2014 Apr 16.

PMID:
24740181
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Limiting amounts of budding yeast Rad53 S-phase checkpoint activity results in increased resistance to DNA alkylation damage.

Cordón-Preciado V, Ufano S, Bueno A.

Nucleic Acids Res. 2006;34(20):5852-62. Epub 2006 Oct 24.

PMID:
17062626
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast.

Raveendranathan M, Chattopadhyay S, Bolon YT, Haworth J, Clarke DJ, Bielinsky AK.

EMBO J. 2006 Aug 9;25(15):3627-39. Epub 2006 Aug 3.

PMID:
16888628
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain.

Pike BL, Tenis N, Heierhorst J.

J Biol Chem. 2004 Sep 17;279(38):39636-44. Epub 2004 Jul 22.

PMID:
15271990
[PubMed - indexed for MEDLINE]
Free Article
17.

Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae.

Hoang ML, Leon RP, Pessoa-Brandao L, Hunt S, Raghuraman MK, Fangman WL, Brewer BJ, Sclafani RA.

Mol Cell Biol. 2007 Nov;27(21):7594-602. Epub 2007 Aug 27.

PMID:
17724082
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The level of origin firing inversely affects the rate of replication fork progression.

Zhong Y, Nellimoottil T, Peace JM, Knott SR, Villwock SK, Yee JM, Jancuska JM, Rege S, Tecklenburg M, Sclafani RA, Tavaré S, Aparicio OM.

J Cell Biol. 2013 Apr 29;201(3):373-83. doi: 10.1083/jcb.201208060.

PMID:
23629964
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.

Sheu YJ, Stillman B.

Nature. 2010 Jan 7;463(7277):113-7. doi: 10.1038/nature08647.

PMID:
20054399
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase.

Shimada K, Pasero P, Gasser SM.

Genes Dev. 2002 Dec 15;16(24):3236-52.

PMID:
12502744
[PubMed - indexed for MEDLINE]
Free PMC Article

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