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Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling.

Biehs B, Kechris K, Liu S, Kornberg TB.

Development. 2010 Nov;137(22):3887-98. doi: 10.1242/dev.055871.


Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila.

Gallet A, Angelats C, Kerridge S, Thérond PP.

Development. 2000 Dec;127(24):5509-22.


Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.

Dussillol-Godar F, Brissard-Zahraoui J, Limbourg-Bouchon B, Boucher D, Fouix S, Lamour-Isnard C, Plessis A, Busson D.

Dev Biol. 2006 Mar 1;291(1):53-66. Epub 2006 Jan 18.


An absolute requirement for Cubitus interruptus in Hedgehog signaling.

Méthot N, Basler K.

Development. 2001 Mar;128(5):733-42.


Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein.

Von Ohlen T, Lessing D, Nusse R, Hooper JE.

Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2404-9.


A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J.

Dev Cell. 2006 Jun;10(6):719-29.


Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes.

Hepker J, Wang QT, Motzny CK, Holmgren R, Orenic TV.

Development. 1997 Jan;124(2):549-58.


Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.


Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.

Kent D, Bush EW, Hooper JE.

Development. 2006 May;133(10):2001-10.


Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development.

Milla LA, Cortés CR, Hodar C, Oñate MG, Cambiazo V, Burgess SM, Palma V.

BMC Genomics. 2012 Jan 3;13:2. doi: 10.1186/1471-2164-13-2.


Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling.

Schwend T, Jin Z, Jiang K, Mitchell BJ, Jia J, Yang J.

J Biol Chem. 2013 Nov 8;288(45):32809-20. doi: 10.1074/jbc.M113.512962. Epub 2013 Sep 26.


Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor.

Aza-Blanc P, Ramírez-Weber FA, Laget MP, Schwartz C, Kornberg TB.

Cell. 1997 Jun 27;89(7):1043-53.


Genetic and epigenetic mechanisms regulating hedgehog expression in the Drosophila wing.

Bejarano F, Milán M.

Dev Biol. 2009 Mar 15;327(2):508-15. doi: 10.1016/j.ydbio.2009.01.006. Epub 2009 Jan 13.


The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control.

Mosimann C, Hausmann G, Basler K.

Mech Dev. 2009 May-Jun;126(5-6):394-405. doi: 10.1016/j.mod.2009.02.002. Epub 2009 Feb 11.

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