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Items: 1 to 20 of 286

1.

EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair.

Zhang M, Ho HC, Sheu TJ, Breyer MD, Flick LM, Jonason JH, Awad HA, Schwarz EM, O'Keefe RJ.

J Bone Miner Res. 2011 Apr;26(4):792-802. doi: 10.1002/jbmr.272.

2.

Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing.

Wang T, Wang Y, Menendez A, Fong C, Babey M, Tahimic CG, Cheng Z, Li A, Chang W, Bikle DD.

J Bone Miner Res. 2015 Sep;30(9):1572-84. doi: 10.1002/jbmr.2510.

PMID:
25801198
3.

Low-dose X-ray irradiation promotes osteoblast proliferation, differentiation and fracture healing.

Chen M, Huang Q, Xu W, She C, Xie ZG, Mao YT, Dong QR, Ling M.

PLoS One. 2014 Aug 4;9(8):e104016. doi: 10.1371/journal.pone.0104016. eCollection 2014.

4.

Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro.

Choudhary S, Blackwell K, Voznesensky O, Deb Roy A, Pilbeam C.

Bone. 2013 Sep;56(1):31-41. doi: 10.1016/j.bone.2013.04.017. Epub 2013 Apr 29.

5.

SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL.

Tsujisawa T, Inoue H, Nishihara T.

J Bone Miner Res. 2005 Jan;20(1):15-22. Epub 2004 Oct 18.

6.

A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivo.

Carroll SH, Wigner NA, Kulkarni N, Johnston-Cox H, Gerstenfeld LC, Ravid K.

J Biol Chem. 2012 May 4;287(19):15718-27. doi: 10.1074/jbc.M112.344994. Epub 2012 Mar 8.

7.

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs.

Suzawa T, Miyaura C, Inada M, Maruyama T, Sugimoto Y, Ushikubi F, Ichikawa A, Narumiya S, Suda T.

Endocrinology. 2000 Apr;141(4):1554-9.

PMID:
10746663
8.

Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.

Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X.

Am J Pathol. 2009 Aug;175(2):772-85. doi: 10.2353/ajpath.2009.081099. Epub 2009 Jul 23.

9.

Haploinsufficiency of endogenous parathyroid hormone-related peptide impairs bone fracture healing.

Wang YH, Qiu Y, Han XD, Xiong J, Chen YX, Shi HF, Karaplis A.

Clin Exp Pharmacol Physiol. 2013 Nov;40(11):715-23. doi: 10.1111/1440-1681.12161.

PMID:
23937065
10.

Systemic inhibition of canonical Notch signaling results in sustained callus inflammation and alters multiple phases of fracture healing.

Dishowitz MI, Mutyaba PL, Takacs JD, Barr AM, Engiles JB, Ahn J, Hankenson KD.

PLoS One. 2013 Jul 3;8(7):e68726. doi: 10.1371/journal.pone.0068726. Print 2013.

11.

Reduced COX-2 expression in aged mice is associated with impaired fracture healing.

Naik AA, Xie C, Zuscik MJ, Kingsley P, Schwarz EM, Awad H, Guldberg R, Drissi H, Puzas JE, Boyce B, Zhang X, O'Keefe RJ.

J Bone Miner Res. 2009 Feb;24(2):251-64. doi: 10.1359/jbmr.081002.

12.

Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice.

Li M, Healy DR, Li Y, Simmons HA, Crawford DT, Ke HZ, Pan LC, Brown TA, Thompson DD.

Bone. 2005 Jul;37(1):46-54.

PMID:
15869929
13.

Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity.

Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT.

J Bone Miner Res. 2007 Apr;22(4):560-8.

14.

Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells.

Sanuki R, Shionome C, Kuwabara A, Mitsui N, Koyama Y, Suzuki N, Zhang F, Shimizu N, Maeno M.

Connect Tissue Res. 2010 Apr;51(2):150-8. doi: 10.3109/03008200903168484.

PMID:
20001844
15.

Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells.

Ikushima YM, Arai F, Hosokawa K, Toyama H, Takubo K, Furuyashiki T, Narumiya S, Suda T.

Blood. 2013 Mar 14;121(11):1995-2007. doi: 10.1182/blood-2012-06-437889. Epub 2013 Jan 11.

16.

Increased fracture callus mineralization and strength in cathepsin K knockout mice.

Gentile MA, Soung do Y, Horrell C, Samadfam R, Drissi H, Duong LT.

Bone. 2014 Sep;66:72-81. doi: 10.1016/j.bone.2014.04.032. Epub 2014 Jun 10. Erratum in: Bone. 2015 Feb;71:264.

PMID:
24928497
17.

Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing.

Kawakatsu M, Kanno S, Gui T, Gai Z, Itoh S, Tanishima H, Oikawa K, Muragaki Y.

Exp Mol Pathol. 2011 Feb;90(1):107-15. doi: 10.1016/j.yexmp.2010.10.011. Epub 2010 Oct 28.

PMID:
21035443
18.

Coenzyme q10 regulates osteoclast and osteoblast differentiation.

Moon HJ, Ko WK, Jung MS, Kim JH, Lee WJ, Park KS, Heo JK, Bang JB, Kwon IK.

J Food Sci. 2013 May;78(5):H785-891. doi: 10.1111/1750-3841.12116. Epub 2013 Apr 12.

PMID:
23582186
19.

Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling.

Gerstenfeld LC, Cho TJ, Kon T, Aizawa T, Cruceta J, Graves BD, Einhorn TA.

Cells Tissues Organs. 2001;169(3):285-94.

PMID:
11455125
20.

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification.

Niedermair T, Kuhn V, Doranehgard F, Stange R, Wieskötter B, Beckmann J, Salmen P, Springorum HR, Straub RH, Zimmer A, Grifka J, Grässel S.

Matrix Biol. 2014 Sep;38:22-35. doi: 10.1016/j.matbio.2014.06.007. Epub 2014 Jul 22.

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