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Items: 1 to 20 of 115


The C terminus of Rpt3, an ATPase subunit of PA700 (19 S) regulatory complex, is essential for 26 S proteasome assembly but not for activation.

Kumar B, Kim YC, DeMartino GN.

J Biol Chem. 2010 Dec 10;285(50):39523-35. doi: 10.1074/jbc.M110.153627. Epub 2010 Oct 11.


C termini of proteasomal ATPases play nonequivalent roles in cellular assembly of mammalian 26 S proteasome.

Kim YC, DeMartino GN.

J Biol Chem. 2011 Jul 29;286(30):26652-66. doi: 10.1074/jbc.M111.246793. Epub 2011 May 31.


Subcomplexes of PA700, the 19 S regulator of the 26 S proteasome, reveal relative roles of AAA subunits in 26 S proteasome assembly and activation and ATPase activity.

Thompson D, Hakala K, DeMartino GN.

J Biol Chem. 2009 Sep 11;284(37):24891-903. doi: 10.1074/jbc.M109.023218. Epub 2009 Jul 9.


Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome.

Gillette TG, Kumar B, Thompson D, Slaughter CA, DeMartino GN.

J Biol Chem. 2008 Nov 14;283(46):31813-22. doi: 10.1074/jbc.M805935200. Epub 2008 Sep 16.


Stable incorporation of ATPase subunits into 19 S regulatory particle of human proteasome requires nucleotide binding and C-terminal tails.

Lee SH, Moon JH, Yoon SK, Yoon JB.

J Biol Chem. 2012 Mar 16;287(12):9269-79. doi: 10.1074/jbc.M111.316208. Epub 2012 Jan 24.


Structural basis for specific recognition of Rpt1p, an ATPase subunit of 26 S proteasome, by proteasome-dedicated chaperone Hsm3p.

Takagi K, Kim S, Yukii H, Ueno M, Morishita R, Endo Y, Kato K, Tanaka K, Saeki Y, Mizushima T.

J Biol Chem. 2012 Apr 6;287(15):12172-82. doi: 10.1074/jbc.M112.345876. Epub 2012 Feb 8.


Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function.

Li X, Thompson D, Kumar B, DeMartino GN.

J Biol Chem. 2014 Jun 20;289(25):17392-405. doi: 10.1074/jbc.M114.561183. Epub 2014 Apr 25.


ATP binding by proteasomal ATPases regulates cellular assembly and substrate-induced functions of the 26 S proteasome.

Kim YC, Li X, Thompson D, DeMartino GN.

J Biol Chem. 2013 Feb 1;288(5):3334-45. doi: 10.1074/jbc.M112.424788. Epub 2012 Dec 4.


An asymmetric interface between the regulatory and core particles of the proteasome.

Tian G, Park S, Lee MJ, Huck B, McAllister F, Hill CP, Gygi SP, Finley D.

Nat Struct Mol Biol. 2011 Oct 30;18(11):1259-67. doi: 10.1038/nsmb.2147.


Functional asymmetries of proteasome translocase pore.

Erales J, Hoyt MA, Troll F, Coffino P.

J Biol Chem. 2012 May 25;287(22):18535-43. doi: 10.1074/jbc.M112.357327. Epub 2012 Apr 5.


An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome.

Förster F, Lasker K, Beck F, Nickell S, Sali A, Baumeister W.

Biochem Biophys Res Commun. 2009 Oct 16;388(2):228-33. doi: 10.1016/j.bbrc.2009.07.145. Epub 2009 Aug 3.


Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.

Smith DM, Chang SC, Park S, Finley D, Cheng Y, Goldberg AL.

Mol Cell. 2007 Sep 7;27(5):731-44.


Reconstitution of PA700, the 19S regulatory particle, from purified precursor complexes.

Demartino GN.

Methods Mol Biol. 2012;832:443-52. doi: 10.1007/978-1-61779-474-2_31.


Assembly manual for the proteasome regulatory particle: the first draft.

Park S, Tian G, Roelofs J, Finley D.

Biochem Soc Trans. 2010 Feb;38(Pt 1):6-13. doi: 10.1042/BST0380006. Review.


Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly.

Tomko RJ Jr, Funakoshi M, Schneider K, Wang J, Hochstrasser M.

Mol Cell. 2010 May 14;38(3):393-403. doi: 10.1016/j.molcel.2010.02.035.


Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.

Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y.

EMBO J. 2010 Feb 3;29(3):692-702. doi: 10.1038/emboj.2009.382. Epub 2009 Dec 17.


Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasome.

Nakamura Y, Umehara T, Tanaka A, Horikoshi M, Padmanabhan B, Yokoyama S.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):503-9. Epub 2007 May 29.


The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome.

Peth A, Nathan JA, Goldberg AL.

J Biol Chem. 2013 Oct 4;288(40):29215-22. doi: 10.1074/jbc.M113.482570. Epub 2013 Aug 21.


N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome Function.

Inobe T, Genmei R.

PLoS One. 2015 Jul 24;10(7):e0134056. doi: 10.1371/journal.pone.0134056. eCollection 2015.

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