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Results: 1 to 20 of 105

1.

Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.

Niu N, Qin Y, Fridley BL, Hou J, Kalari KR, Zhu M, Wu TY, Jenkins GD, Batzler A, Wang L.

Genome Res. 2010 Nov;20(11):1482-92. doi: 10.1101/gr.107672.110. Epub 2010 Oct 5.

PMID:
20923822
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers.

Li L, Fridley BL, Kalari K, Jenkins G, Batzler A, Weinshilboum RM, Wang L.

PLoS One. 2009 Nov 9;4(11):e7765. doi: 10.1371/journal.pone.0007765.

PMID:
19898621
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.

Jiang J, Fridley BL, Feng Q, Abo RP, Brisbin A, Batzler A, Jenkins G, Long PA, Wang L.

Front Genet. 2013 Aug 30;4:166. doi: 10.3389/fgene.2013.00166. eCollection 2013.

PMID:
24009623
[PubMed]
Free PMC Article
4.

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

Niu N, Schaid DJ, Abo RP, Kalari K, Fridley BL, Feng Q, Jenkins G, Batzler A, Brisbin AG, Cunningham JM, Li L, Sun Z, Yang P, Wang L.

BMC Cancer. 2012 Sep 24;12:422. doi: 10.1186/1471-2407-12-422.

PMID:
23006423
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

Tan XL, Moyer AM, Fridley BL, Schaid DJ, Niu N, Batzler AJ, Jenkins GD, Abo RP, Li L, Cunningham JM, Sun Z, Yang P, Wang L.

Clin Cancer Res. 2011 Sep 1;17(17):5801-11. doi: 10.1158/1078-0432.CCR-11-1133. Epub 2011 Jul 20.

PMID:
21775533
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

Li L, Fridley BL, Kalari K, Niu N, Jenkins G, Batzler A, Abo RP, Schaid D, Wang L.

BMC Genomics. 2014 Feb 1;15:93. doi: 10.1186/1471-2164-15-93.

PMID:
24483146
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.

Kalari KR, Hebbring SJ, Chai HS, Li L, Kocher JP, Wang L, Weinshilboum RM.

BMC Genomics. 2010 Jun 4;11:357. doi: 10.1186/1471-2164-11-357.

PMID:
20525348
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation.

Weng L, Ziliak D, Im HK, Gamazon ER, Philips S, Nguyen AT, Desta Z, Skaar TC; Consortium on Breast Cancer Pharmacogenomics (COBRA), Flockhart DA, Huang RS.

Ann Oncol. 2013 Jul;24(7):1867-73. doi: 10.1093/annonc/mdt125. Epub 2013 Mar 18.

PMID:
23508821
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen.

Wu TY, Fridley BL, Jenkins GD, Batzler A, Wang L, Weinshilboum RM.

Int Immunopharmacol. 2011 Aug;11(8):1057-64. doi: 10.1016/j.intimp.2011.02.027. Epub 2011 Mar 23.

PMID:
21396482
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.

Huang RS, Johnatty SE, Gamazon ER, Im HK, Ziliak D, Duan S, Zhang W, Kistner EO, Chen P, Beesley J, Mi S, O'Donnell PH, Fraiman YS, Das S, Cox NJ, Lu Y, Macgregor S, Goode EL, Vierkant RA, Fridley BL, Hogdall E, Kjaer SK, Jensen A, Moysich KB, Grasela M, Odunsi K, Brown R, Paul J, Lambrechts D, Despierre E, Vergote I, Gross J, Karlan BY, Defazio A, Chenevix-Trench G; Australian Ovarian Cancer Study Group, Dolan ME.

Clin Cancer Res. 2011 Aug 15;17(16):5490-500. doi: 10.1158/1078-0432.CCR-11-0724. Epub 2011 Jun 24.

PMID:
21705454
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.

Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, Schaid DJ, Nakamura Y, Weinshilboum RM.

Mol Endocrinol. 2013 Apr;27(4):657-70. doi: 10.1210/me.2012-1397. Epub 2013 Mar 21.

PMID:
23518928
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Integrative gene set analysis: application to platinum pharmacogenomics.

Fridley BL, Abo R, Tan XL, Jenkins GD, Batzler A, Moyer AM, Biernacka JM, Wang L.

OMICS. 2014 Jan;18(1):34-41. doi: 10.1089/omi.2013.0099. Epub 2013 Nov 7.

PMID:
24199607
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study.

Moyer AM, Fridley BL, Jenkins GD, Batzler AJ, Pelleymounter LL, Kalari KR, Ji Y, Chai Y, Nordgren KK, Weinshilboum RM.

Toxicol Sci. 2011 Mar;120(1):33-41. doi: 10.1093/toxsci/kfq375. Epub 2010 Dec 22.

PMID:
21177773
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

Brown CC, Havener TM, Medina MW, Auman JT, Mangravite LM, Krauss RM, McLeod HL, Motsinger-Reif AA.

Pharmacogenet Genomics. 2012 Nov;22(11):796-802. doi: 10.1097/FPC.0b013e3283589c50.

PMID:
23047291
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Population genomics in a disease targeted primary cell model.

Grundberg E, Kwan T, Ge B, Lam KC, Koka V, Kindmark A, Mallmin H, Dias J, Verlaan DJ, Ouimet M, Sinnett D, Rivadeneira F, Estrada K, Hofman A, van Meurs JM, Uitterlinden A, Beaulieu P, Graziani A, Harmsen E, Ljunggren O, Ohlsson C, Mellström D, Karlsson MK, Nilsson O, Pastinen T.

Genome Res. 2009 Nov;19(11):1942-52. doi: 10.1101/gr.095224.109. Epub 2009 Aug 4.

PMID:
19654370
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits.

Min JL, Taylor JM, Richards JB, Watts T, Pettersson FH, Broxholme J, Ahmadi KR, Surdulescu GL, Lowy E, Gieger C, Newton-Cheh C, Perola M, Soranzo N, Surakka I, Lindgren CM, Ragoussis J, Morris AP, Cardon LR, Spector TD, Zondervan KT.

PLoS One. 2011;6(7):e22070. doi: 10.1371/journal.pone.0022070. Epub 2011 Jul 15.

PMID:
21789213
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genetic and epigenetic variants contributing to clofarabine cytotoxicity.

Eadon MT, Wheeler HE, Stark AL, Zhang X, Moen EL, Delaney SM, Im HK, Cunningham PN, Zhang W, Dolan ME.

Hum Mol Genet. 2013 Oct 1;22(19):4007-20. doi: 10.1093/hmg/ddt240. Epub 2013 May 29.

PMID:
23720496
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines.

Eng L, Ibrahim-zada I, Jarjanazi H, Savas S, Meschian M, Pritchard KI, Ozcelik H.

BMC Med Genomics. 2011 Feb 11;4:18. doi: 10.1186/1755-8794-4-18.

PMID:
21314952
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer.

Kerns SL, Stock R, Stone N, Buckstein M, Shao Y, Campbell C, Rath L, De Ruysscher D, Lammering G, Hixson R, Cesaretti J, Terk M, Ostrer H, Rosenstein BS.

Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):e21-8. doi: 10.1016/j.ijrobp.2012.08.003. Epub 2012 Sep 26.

PMID:
23021708
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Functional consequences of PRPF39 on distant genes and cisplatin sensitivity.

Stark AL, Delaney SM, Wheeler HE, Im HK, Dolan ME.

Hum Mol Genet. 2012 Oct 1;21(19):4348-55. doi: 10.1093/hmg/dds266. Epub 2012 Jul 5.

PMID:
22773733
[PubMed - indexed for MEDLINE]
Free PMC Article

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