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Results: 1 to 20 of 269

1.

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.

Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR.

Arch Gen Psychiatry. 2010 Oct;67(10):991-1001. doi: 10.1001/archgenpsychiatry.2010.117.

PMID:
20921115
[PubMed - indexed for MEDLINE]
2.

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK, Vakkalanka R, Giegling I, Rujescu D, St Clair D, Muglia P, Shugart YY, Weinberger DR.

Hum Genet. 2010 Apr;127(4):441-52. doi: 10.1007/s00439-009-0782-y. Erratum in: Hum Genet. 2010 Apr;127(4):453-4.

PMID:
20084519
[PubMed - indexed for MEDLINE]
3.

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.

Norton N, Moskvina V, Morris DW, Bray NJ, Zammit S, Williams NM, Williams HJ, Preece AC, Dwyer S, Wilkinson JC, Spurlock G, Kirov G, Buckland P, Waddington JL, Gill M, Corvin AP, Owen MJ, O'Donovan MC.

Am J Med Genet B Neuropsychiatr Genet. 2006 Jan 5;141B(1):96-101.

PMID:
16249994
[PubMed - indexed for MEDLINE]
4.

Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications.

Tan HY, Chen AG, Chen Q, Browne LB, Verchinski B, Kolachana B, Zhang F, Apud J, Callicott JH, Mattay VS, Weinberger DR.

Mol Psychiatry. 2012 Oct;17(10):1007-16. doi: 10.1038/mp.2011.91. Epub 2011 Jul 26.

PMID:
21788944
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.

Thiselton DL, Vladimirov VI, Kuo PH, McClay J, Wormley B, Fanous A, O'Neill FA, Walsh D, Van den Oord EJ, Kendler KS, Riley BP.

Biol Psychiatry. 2008 Mar 1;63(5):449-57. Epub 2007 Sep 6.

PMID:
17825267
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1-ErbB signaling in cell models.

Sei Y, Li Z, Song J, Ren-Patterson R, Tunbridge EM, Iizuka Y, Inoue M, Alfonso BT, Beltaifa S, Nakai Y, Kolachana BS, Chen J, Weinberger DR.

PLoS One. 2010 May 24;5(5):e10789. doi: 10.1371/journal.pone.0010789.

PMID:
20520724
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Striatal response to reward anticipation: evidence for a systems-level intermediate phenotype for schizophrenia.

Grimm O, Heinz A, Walter H, Kirsch P, Erk S, Haddad L, Plichta MM, Romanczuk-Seiferth N, Pöhland L, Mohnke S, Mühleisen TW, Mattheisen M, Witt SH, Schäfer A, Cichon S, Nöthen M, Rietschel M, Tost H, Meyer-Lindenberg A.

JAMA Psychiatry. 2014 May;71(5):531-9. doi: 10.1001/jamapsychiatry.2014.9.

PMID:
24622944
[PubMed - indexed for MEDLINE]
8.

Effective connectivity of AKT1-mediated dopaminergic working memory networks and pharmacogenetics of anti-dopaminergic treatment.

Tan HY, Chen AG, Kolachana B, Apud JA, Mattay VS, Callicott JH, Chen Q, Weinberger DR.

Brain. 2012 May;135(Pt 5):1436-45. doi: 10.1093/brain/aws068. Epub 2012 Apr 23.

PMID:
22525159
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland.

Turunen JA, Peltonen JO, Pietiläinen OP, Hennah W, Loukola A, Paunio T, Silander K, Ekelund J, Varilo T, Partonen T, Lönnqvist J, Peltonen L.

Schizophr Res. 2007 Mar;91(1-3):27-36. Epub 2007 Feb 14.

PMID:
17300918
[PubMed - indexed for MEDLINE]
10.

Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population.

Shiota S, Tochigi M, Shimada H, Ohashi J, Kasai K, Kato N, Tokunaga K, Sasaki T.

J Hum Genet. 2008;53(10):929-35. doi: 10.1007/s10038-008-0332-9. Epub 2008 Aug 14.

PMID:
18704261
[PubMed - indexed for MEDLINE]
11.

Altered cortical network dynamics: a potential intermediate phenotype for schizophrenia and association with ZNF804A.

Rasetti R, Sambataro F, Chen Q, Callicott JH, Mattay VS, Weinberger DR.

Arch Gen Psychiatry. 2011 Dec;68(12):1207-17. doi: 10.1001/archgenpsychiatry.2011.103. Epub 2011 Aug 1.

PMID:
21810628
[PubMed - indexed for MEDLINE]
12.

Discovery, validation and characterization of Erbb4 and Nrg1 haplotypes using data from three genome-wide association studies of schizophrenia.

Agim ZS, Esendal M, Briollais L, Uyan O, Meschian M, Martinez LA, Ding Y, Basak AN, Ozcelik H.

PLoS One. 2013;8(1):e53042. doi: 10.1371/journal.pone.0053042. Epub 2013 Jan 3.

PMID:
23301017
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.

Hahn CG, Wang HY, Cho DS, Talbot K, Gur RE, Berrettini WH, Bakshi K, Kamins J, Borgmann-Winter KE, Siegel SJ, Gallop RJ, Arnold SE.

Nat Med. 2006 Jul;12(7):824-8. Epub 2006 Jun 11.

PMID:
16767099
[PubMed - indexed for MEDLINE]
14.

Support for NRG1 as a susceptibility factor for schizophrenia in a northern Swedish isolated population.

Alaerts M, Ceulemans S, Forero D, Moens LN, De Zutter S, Heyrman L, Lenaerts AS, Norrback KF, De Rijk P, Nilsson LG, Goossens D, Adolfsson R, Del-Favero J.

Arch Gen Psychiatry. 2009 Aug;66(8):828-37. doi: 10.1001/archgenpsychiatry.2009.82.

PMID:
19652122
[PubMed - indexed for MEDLINE]
15.

Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.

Donohoe G, Walters J, Morris DW, Quinn EM, Judge R, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Williams H, Moskvina V, Peel R, O'Donoghue T, Owen MJ, O'Donovan MC, Gill M, Rujescu D, Corvin A.

Arch Gen Psychiatry. 2009 Oct;66(10):1045-54. doi: 10.1001/archgenpsychiatry.2009.139.

PMID:
19805695
[PubMed - indexed for MEDLINE]
16.

Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories.

Addington AM, Gornick MC, Shaw P, Seal J, Gogtay N, Greenstein D, Clasen L, Coffey M, Gochman P, Long R, Rapoport JL.

Mol Psychiatry. 2007 Feb;12(2):195-205. Epub 2006 Oct 10.

PMID:
17033632
[PubMed - indexed for MEDLINE]
17.

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.

Georgieva L, Moskvina V, Peirce T, Norton N, Bray NJ, Jones L, Holmans P, Macgregor S, Zammit S, Wilkinson J, Williams H, Nikolov I, Williams N, Ivanov D, Davis KL, Haroutunian V, Buxbaum JD, Craddock N, Kirov G, Owen MJ, O'Donovan MC.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12469-74. Epub 2006 Aug 4.

PMID:
16891421
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.

Buxbaum JD, Georgieva L, Young JJ, Plescia C, Kajiwara Y, Jiang Y, Moskvina V, Norton N, Peirce T, Williams H, Craddock NJ, Carroll L, Corfas G, Davis KL, Owen MJ, Harroch S, Sakurai T, O'Donovan MC.

Mol Psychiatry. 2008 Feb;13(2):162-72. Epub 2007 Apr 17.

PMID:
17579610
[PubMed - indexed for MEDLINE]
19.

Cumulative genetic risk and prefrontal activity in patients with schizophrenia.

Walton E, Turner J, Gollub RL, Manoach DS, Yendiki A, Ho BC, Sponheim SR, Calhoun VD, Ehrlich S.

Schizophr Bull. 2013 May;39(3):703-11. doi: 10.1093/schbul/sbr190. Epub 2012 Jan 20.

PMID:
22267534
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients.

Chong VZ, Thompson M, Beltaifa S, Webster MJ, Law AJ, Weickert CS.

Schizophr Res. 2008 Mar;100(1-3):270-80. doi: 10.1016/j.schres.2007.12.474. Epub 2008 Feb 19.

PMID:
18243664
[PubMed - indexed for MEDLINE]
Free PMC Article

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