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Items: 1 to 20 of 111

1.

Structure of a major antigenic site on the respiratory syncytial virus fusion glycoprotein in complex with neutralizing antibody 101F.

McLellan JS, Chen M, Chang JS, Yang Y, Kim A, Graham BS, Kwong PD.

J Virol. 2010 Dec;84(23):12236-44. doi: 10.1128/JVI.01579-10. Epub 2010 Sep 29.

2.

Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.

McLellan JS, Yang Y, Graham BS, Kwong PD.

J Virol. 2011 Aug;85(15):7788-96. doi: 10.1128/JVI.00555-11. Epub 2011 May 25.

3.

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.

Swanson KA, Settembre EC, Shaw CA, Dey AK, Rappuoli R, Mandl CW, Dormitzer PR, Carfi A.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9619-24. doi: 10.1073/pnas.1106536108. Epub 2011 May 17.

4.

Structural basis of respiratory syncytial virus neutralization by motavizumab.

McLellan JS, Chen M, Kim A, Yang Y, Graham BS, Kwong PD.

Nat Struct Mol Biol. 2010 Feb;17(2):248-50. doi: 10.1038/nsmb.1723. Epub 2010 Jan 24.

5.

Characterization of neutralizing affinity-matured human respiratory syncytial virus F binding antibodies in the sub-picomolar affinity range.

Canziani GA, Melero JA, Lacy ER.

J Mol Recognit. 2012 Mar;25(3):136-46. doi: 10.1002/jmr.2149.

PMID:
22407977
6.

Mechanism of neutralization of herpes simplex virus by antibodies directed at the fusion domain of glycoprotein B.

Cairns TM, Fontana J, Huang ZY, Whitbeck JC, Atanasiu D, Rao S, Shelly SS, Lou H, Ponce de Leon M, Steven AC, Eisenberg RJ, Cohen GH.

J Virol. 2014 Mar;88(5):2677-89. doi: 10.1128/JVI.03200-13. Epub 2013 Dec 18.

7.

Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein.

Crowe JE, Firestone CY, Crim R, Beeler JA, Coelingh KL, Barbas CF, Burton DR, Chanock RM, Murphy BR.

Virology. 1998 Dec 20;252(2):373-5.

8.

Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein.

Bates JT, Keefer CJ, Slaughter JC, Kulp DW, Schief WR, Crowe JE Jr.

Virology. 2014 Apr;454-455:139-44. doi: 10.1016/j.virol.2014.02.010. Epub 2014 Mar 3.

9.

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency.

Bates JT, Keefer CJ, Utley TJ, Correia BE, Schief WR, Crowe JE Jr.

J Immunol. 2013 Apr 1;190(7):3732-9. doi: 10.4049/jimmunol.1202964. Epub 2013 Mar 1.

10.

A monomeric uncleaved respiratory syncytial virus F antigen retains prefusion-specific neutralizing epitopes.

Swanson KA, Balabanis K, Xie Y, Aggarwal Y, Palomo C, Mas V, Metrick C, Yang H, Shaw CA, Melero JA, Dormitzer PR, Carfi A.

J Virol. 2014 Oct;88(20):11802-10. doi: 10.1128/JVI.01225-14. Epub 2014 Jul 30.

11.

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.

Gilman MS, Moin SM, Mas V, Chen M, Patel NK, Kramer K, Zhu Q, Kabeche SC, Kumar A, Palomo C, Beaumont T, Baxa U, Ulbrandt ND, Melero JA, Graham BS, McLellan JS.

PLoS Pathog. 2015 Jul 10;11(7):e1005035. doi: 10.1371/journal.ppat.1005035. eCollection 2015 Jul.

12.

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.

Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE Jr, Jardetzky TS.

Nat Struct Mol Biol. 2012 Mar 4;19(4):461-3. doi: 10.1038/nsmb.2250.

13.

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody.

Corti D, Bianchi S, Vanzetta F, Minola A, Perez L, Agatic G, Guarino B, Silacci C, Marcandalli J, Marsland BJ, Piralla A, Percivalle E, Sallusto F, Baldanti F, Lanzavecchia A.

Nature. 2013 Sep 19;501(7467):439-43. doi: 10.1038/nature12442. Epub 2013 Aug 18.

PMID:
23955151
14.

Respiratory syncytial virus fusion glycoprotein: further characterization of a major epitope involved in virus neutralization.

Trudel M, Nadon F, Séguin C, Payment P, Talbot PJ.

Can J Microbiol. 1987 Oct;33(10):933-8.

PMID:
2446731
15.

Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody.

Chandramouli S, Ciferri C, Nikitin PA, Caló S, Gerrein R, Balabanis K, Monroe J, Hebner C, Lilja AE, Settembre EC, Carfi A.

Nat Commun. 2015 Sep 14;6:8176. doi: 10.1038/ncomms9176.

16.

Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats.

Smith G, Raghunandan R, Wu Y, Liu Y, Massare M, Nathan M, Zhou B, Lu H, Boddapati S, Li J, Flyer D, Glenn G.

PLoS One. 2012;7(11):e50852. doi: 10.1371/journal.pone.0050852. Epub 2012 Nov 30.

17.

Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.

McLellan JS, Chen M, Leung S, Graepel KW, Du X, Yang Y, Zhou T, Baxa U, Yasuda E, Beaumont T, Kumar A, Modjarrad K, Zheng Z, Zhao M, Xia N, Kwong PD, Graham BS.

Science. 2013 May 31;340(6136):1113-7. doi: 10.1126/science.1234914. Epub 2013 Apr 25.

18.

Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.

McLellan JS, Correia BE, Chen M, Yang Y, Graham BS, Schief WR, Kwong PD.

J Mol Biol. 2011 Jun 24;409(5):853-66. doi: 10.1016/j.jmb.2011.04.044. Epub 2011 Apr 27.

19.

Evaluation of a synthetic peptide as a replacement for the recombinant fusion protein of respiratory syncytial virus in a potency ELISA.

McGivney JB 4th, Bishop E, Miller K, Casas-Finet J, Yang H, Wei Z, Strouse R, Schenerman M.

J Pharm Biomed Anal. 2011 Feb 20;54(3):572-6. doi: 10.1016/j.jpba.2010.09.008. Epub 2010 Sep 16.

PMID:
20943340
20.

Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method.

Evans MC, Phung P, Paquet AC, Parikh A, Petropoulos CJ, Wrin T, Haddad M.

BMC Bioinformatics. 2014 Mar 19;15:77. doi: 10.1186/1471-2105-15-77.

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