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Similar articles for PubMed (Select 20871615)


Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.

Buisson R, Dion-Côté AM, Coulombe Y, Launay H, Cai H, Stasiak AZ, Stasiak A, Xia B, Masson JY.

Nat Struct Mol Biol. 2010 Oct;17(10):1247-54. doi: 10.1038/nsmb.1915. Epub 2010 Sep 26.


Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.

Dray E, Etchin J, Wiese C, Saro D, Williams GJ, Hammel M, Yu X, Galkin VE, Liu D, Tsai MS, Sy SM, Schild D, Egelman E, Chen J, Sung P.

Nat Struct Mol Biol. 2010 Oct;17(10):1255-9. doi: 10.1038/nsmb.1916. Epub 2010 Sep 26.


Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.

Park JY, Singh TR, Nassar N, Zhang F, Freund M, Hanenberg H, Meetei AR, Andreassen PR.

Oncogene. 2014 Oct 2;33(40):4803-12. doi: 10.1038/onc.2013.421. Epub 2013 Oct 21.


Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

Liu J, Doty T, Gibson B, Heyer WD.

Nat Struct Mol Biol. 2010 Oct;17(10):1260-2. doi: 10.1038/nsmb.1904. Epub 2010 Aug 22.


The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

Thorslund T, McIlwraith MJ, Compton SA, Lekomtsev S, Petronczki M, Griffith JD, West SC.

Nat Struct Mol Biol. 2010 Oct;17(10):1263-5. doi: 10.1038/nsmb.1905. Epub 2010 Aug 22.


Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

Siaud N, Barbera MA, Egashira A, Lam I, Christ N, Schlacher K, Xia B, Jasin M.

PLoS Genet. 2011 Dec;7(12):e1002409. doi: 10.1371/journal.pgen.1002409. Epub 2011 Dec 15.


PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.

Zhang F, Fan Q, Ren K, Andreassen PR.

Mol Cancer Res. 2009 Jul;7(7):1110-8. doi: 10.1158/1541-7786.MCR-09-0123. Epub 2009 Jul 7.


PALB2 regulates recombinational repair through chromatin association and oligomerization.

Sy SM, Huen MS, Zhu Y, Chen J.

J Biol Chem. 2009 Jul 3;284(27):18302-10. doi: 10.1074/jbc.M109.016717. Epub 2009 May 7.


PALB2: the hub of a network of tumor suppressors involved in DNA damage responses.

Park JY, Zhang F, Andreassen PR.

Biochim Biophys Acta. 2014 Aug;1846(1):263-75. doi: 10.1016/j.bbcan.2014.06.003. Epub 2014 Jul 3. Review.


Structural basis for recruitment of BRCA2 by PALB2.

Oliver AW, Swift S, Lord CJ, Ashworth A, Pearl LH.

EMBO Rep. 2009 Sep;10(9):990-6. doi: 10.1038/embor.2009.126. Epub 2009 Jul 17.


Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks.

Buisson R, Niraj J, Pauty J, Maity R, Zhao W, Coulombe Y, Sung P, Masson JY.

Cell Rep. 2014 Feb 13;6(3):553-64. doi: 10.1016/j.celrep.2014.01.009. Epub 2014 Jan 30.


Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.

Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C, Livingston DM.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8632-7. doi: 10.1073/pnas.1305362110. Epub 2013 May 8.


[Functions of PALB2 and BRCA2 tumor suppressors in DNA double-strand break repair].

Buisson R, Masson JY.

Med Sci (Paris). 2013 Mar;29(3):301-7. doi: 10.1051/medsci/2013293017. Epub 2013 Mar 27. Review. French.


PALB2 self-interaction controls homologous recombination.

Buisson R, Masson JY.

Nucleic Acids Res. 2012 Nov 1;40(20):10312-23. doi: 10.1093/nar/gks807. Epub 2012 Aug 31.


Structural insights into BRCA2 function.

Shamoo Y.

Curr Opin Struct Biol. 2003 Apr;13(2):206-11. Review.


RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination.

Lok BH, Carley AC, Tchang B, Powell SN.

Oncogene. 2013 Jul 25;32(30):3552-8. doi: 10.1038/onc.2012.391. Epub 2012 Sep 10.


Unraveling the mechanism of BRCA2 in homologous recombination.

Holloman WK.

Nat Struct Mol Biol. 2011 Jul 6;18(7):748-54. doi: 10.1038/nsmb.2096. Review.


Exploring the roles of PALB2 at the crossroads of DNA repair and cancer.

Pauty J, Rodrigue A, Couturier A, Buisson R, Masson JY.

Biochem J. 2014 Jun 15;460(3):331-42. doi: 10.1042/BJ20140208. Review. Erratum in: Biochem J. 2014 Aug 1;461(3):539.


BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.

Yang H, Jeffrey PD, Miller J, Kinnucan E, Sun Y, Thoma NH, Zheng N, Chen PL, Lee WH, Pavletich NP.

Science. 2002 Sep 13;297(5588):1837-48.

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