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Results: 1 to 20 of 103

1.

Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease.

Valles F, Fiandaca MS, Eberling JL, Starr PA, Larson PS, Christine CW, Forsayeth J, Richardson RM, Su X, Aminoff MJ, Bankiewicz KS.

Neurosurgery. 2010 Nov;67(5):1377-85. doi: 10.1227/NEU.0b013e3181f53a5c.

PMID:
20871425
[PubMed - indexed for MEDLINE]
2.

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease.

Eberling JL, Jagust WJ, Christine CW, Starr P, Larson P, Bankiewicz KS, Aminoff MJ.

Neurology. 2008 May 20;70(21):1980-3. doi: 10.1212/01.wnl.0000312381.29287.ff. Epub 2008 Apr 9.

PMID:
18401019
[PubMed - indexed for MEDLINE]
3.

Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats.

Sánchez-Pernaute R, Harvey-White J, Cunningham J, Bankiewicz KS.

Mol Ther. 2001 Oct;4(4):324-30.

PMID:
11592835
[PubMed - indexed for MEDLINE]
Free Article
4.

Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease.

Mittermeyer G, Christine CW, Rosenbluth KH, Baker SL, Starr P, Larson P, Kaplan PL, Forsayeth J, Aminoff MJ, Bankiewicz KS.

Hum Gene Ther. 2012 Apr;23(4):377-81. doi: 10.1089/hum.2011.220. Epub 2012 Apr 10.

PMID:
22424171
[PubMed - indexed for MEDLINE]
5.

Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach.

Bankiewicz KS, Eberling JL, Kohutnicka M, Jagust W, Pivirotto P, Bringas J, Cunningham J, Budinger TF, Harvey-White J.

Exp Neurol. 2000 Jul;164(1):2-14.

PMID:
10877910
[PubMed - indexed for MEDLINE]
6.

Biodistribution of adeno-associated virus type-2 in nonhuman primates after convection-enhanced delivery to brain.

Cunningham J, Pivirotto P, Bringas J, Suzuki B, Vijay S, Sanftner L, Kitamura M, Chan C, Bankiewicz KS.

Mol Ther. 2008 Jul;16(7):1267-75. doi: 10.1038/mt.2008.111. Epub 2008 Jun 3.

PMID:
18523450
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease.

Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ.

Neurology. 2009 Nov 17;73(20):1662-9. doi: 10.1212/WNL.0b013e3181c29356. Epub 2009 Oct 14.

PMID:
19828868
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.

Shen Y, Muramatsu SI, Ikeguchi K, Fujimoto KI, Fan DS, Ogawa M, Mizukami H, Urabe M, Kume A, Nagatsu I, Urano F, Suzuki T, Ichinose H, Nagatsu T, Monahan J, Nakano I, Ozawa K.

Hum Gene Ther. 2000 Jul 20;11(11):1509-19.

PMID:
10945765
[PubMed - indexed for MEDLINE]
9.

AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters.

Sanftner LM, Sommer JM, Suzuki BM, Smith PH, Vijay S, Vargas JA, Forsayeth JR, Cunningham J, Bankiewicz KS, Kao H, Bernal J, Pierce GF, Johnson KW.

Exp Neurol. 2005 Aug;194(2):476-83.

PMID:
16022872
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain.

Hadaczek P, Kohutnicka M, Krauze MT, Bringas J, Pivirotto P, Cunningham J, Bankiewicz K.

Hum Gene Ther. 2006 Mar;17(3):291-302.

PMID:
16544978
[PubMed - indexed for MEDLINE]
11.

[Gene therapy for Parkinson's disease].

Muramatsu S.

Nihon Rinsho. 2005 Dec;63 Suppl 12:622-5. Review. Japanese. No abstract available.

PMID:
16416863
[PubMed - indexed for MEDLINE]
12.

Gene therapy of Parkinson's disease using adeno-associated virus (AAV) vectors.

Ozawa K, Fan DS, Shen Y, Muramatsu S, Fujimoto K, Ikeguchi K, Ogawa M, Urabe M, Kume A, Nakano I.

J Neural Transm Suppl. 2000;(58):181-91. Review.

PMID:
11128607
[PubMed - indexed for MEDLINE]
13.
14.

[AAV vector-mediated gene transfer and its application to the nervous system].

Ozawa K.

Rinsho Shinkeigaku. 2003 Nov;43(11):835-8. Review. Japanese.

PMID:
15152479
[PubMed - indexed for MEDLINE]
15.

A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys.

Forsayeth JR, Eberling JL, Sanftner LM, Zhen Z, Pivirotto P, Bringas J, Cunningham J, Bankiewicz KS.

Mol Ther. 2006 Oct;14(4):571-7. Epub 2006 Jun 16.

PMID:
16781894
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.

Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, Terao K, Nakano I, Ozawa K.

Hum Gene Ther. 2002 Feb 10;13(3):345-54.

PMID:
11860702
[PubMed - indexed for MEDLINE]
17.

A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease.

Muramatsu S, Fujimoto K, Kato S, Mizukami H, Asari S, Ikeguchi K, Kawakami T, Urabe M, Kume A, Sato T, Watanabe E, Ozawa K, Nakano I.

Mol Ther. 2010 Sep;18(9):1731-5. doi: 10.1038/mt.2010.135. Epub 2010 Jul 6.

PMID:
20606642
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Distribution of AAV2-hAADC-transduced cells after 3 years in Parkinsonian monkeys.

Daadi MM, Pivirotto P, Bringas J, Cunningham J, Forsayeth J, Eberling J, Bankiewicz KS.

Neuroreport. 2006 Feb 6;17(2):201-4. Erratum in: Neuroreport. 2006 Mar 20;17(4):453.

PMID:
16407771
[PubMed - indexed for MEDLINE]
19.

[Gene therapy using AAV].

Ozawa K.

Uirusu. 2007 Jun;57(1):47-55. Review. Japanese.

PMID:
18040154
[PubMed - indexed for MEDLINE]
Free Article
20.

NLX-P101, an adeno-associated virus gene therapy encoding glutamic acid decarboxylase, for the potential treatment of Parkinson's disease.

Diaz-Nido J.

Curr Opin Investig Drugs. 2010 Jul;11(7):813-22.

PMID:
20571977
[PubMed - indexed for MEDLINE]

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