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Results: 1 to 20 of 132

1.

t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL.

Kumar AR, Yao Q, Li Q, Sam TA, Kersey JH.

Leuk Res. 2011 Mar;35(3):305-9. doi: 10.1016/j.leukres.2010.08.011. Epub 2010 Sep 25.

PMID:
20869771
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.

Gessner A, Thomas M, Castro PG, Büchler L, Scholz A, Brümmendorf TH, Soria NM, Vormoor J, Greil J, Heidenreich O.

Leukemia. 2010 Oct;24(10):1751-9. doi: 10.1038/leu.2010.155. Epub 2010 Aug 5.

PMID:
20686504
[PubMed - indexed for MEDLINE]
3.

Significance of AF4-MLL reciprocal fusion in t(4;11) leukemias?

Sanders DS, Muntean AG, Hess JL.

Leuk Res. 2011 Mar;35(3):299-300. doi: 10.1016/j.leukres.2010.09.015. Epub 2010 Oct 16. No abstract available.

PMID:
20952059
[PubMed - indexed for MEDLINE]
4.

Authors' comments: t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL.

Kumar AR, Yao Q, Li Q, Sam TA, Kersey JH.

Leuk Res. 2011 May;35(5):697. doi: 10.1016/j.leukres.2010.12.025. Epub 2011 Jan 31. No abstract available.

PMID:
21277021
[PubMed - indexed for MEDLINE]
5.

The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia.

Pless B, Oehm C, Knauer S, Stauber RH, Dingermann T, Marschalek R.

Leukemia. 2011 Apr;25(4):663-70. doi: 10.1038/leu.2010.308. Epub 2011 Jan 14.

PMID:
21233834
[PubMed - indexed for MEDLINE]
6.

Cryptic splice site activation during RNA processing of MLL/AF4 chimeric transcripts in infants with t(4;11) positive ALL.

Divoky V, Trka JM, Watzinger F, Lion T.

Gene. 2000 Apr 18;247(1-2):111-8.

PMID:
10773450
[PubMed - indexed for MEDLINE]
7.

It takes two-to-leukemia: about addictions and requirements.

Marschalek R.

Leuk Res. 2011 Mar;35(3):424-5. doi: 10.1016/j.leukres.2010.10.003. Epub 2010 Nov 11. No abstract available.

PMID:
21074267
[PubMed - indexed for MEDLINE]
8.

AF4 encodes a ubiquitous protein that in both native and MLL-AF4 fusion types localizes to subnuclear compartments.

Li Q, Frestedt JL, Kersey JH.

Blood. 1998 Nov 15;92(10):3841-7.

PMID:
9808577
[PubMed - indexed for MEDLINE]
Free Article
9.

Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation.

Uckun FM, Herman-Hatten K, Crotty ML, Sensel MG, Sather HN, Tuel-Ahlgren L, Sarquis MB, Bostrom B, Nachman JB, Steinherz PG, Gaynon PS, Heerema N.

Blood. 1998 Aug 1;92(3):810-21.

PMID:
9680349
[PubMed - indexed for MEDLINE]
Free Article
10.

Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.

Gaussmann A, Wenger T, Eberle I, Bursen A, Bracharz S, Herr I, Dingermann T, Marschalek R.

Oncogene. 2007 May 17;26(23):3352-63. Epub 2006 Nov 27.

PMID:
17130830
[PubMed - indexed for MEDLINE]
11.

Targeting MLL-AF4 with short interfering RNAs inhibits clonogenicity and engraftment of t(4;11)-positive human leukemic cells.

Thomas M, Gessner A, Vornlocher HP, Hadwiger P, Greil J, Heidenreich O.

Blood. 2005 Nov 15;106(10):3559-66. Epub 2005 Jul 26.

PMID:
16046533
[PubMed - indexed for MEDLINE]
Free Article
12.

Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.

Bennett CA, Winters AC, Barretto NN, Hemenway CS.

Leuk Res. 2009 Jul;33(7):937-47. doi: 10.1016/j.leukres.2009.01.018. Epub 2009 Feb 20.

PMID:
19232721
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The synthetic peptide PFWT disrupts AF4-AF9 protein complexes and induces apoptosis in t(4;11) leukemia cells.

Srinivasan RS, Nesbit JB, Marrero L, Erfurth F, LaRussa VF, Hemenway CS.

Leukemia. 2004 Aug;18(8):1364-72.

PMID:
15269783
[PubMed - indexed for MEDLINE]
14.

t(10;11)-acute leukemias with MLL-AF10 and MLL-ABI1 chimeric transcripts: specific expression patterns of ABI1 gene in leukemia and solid tumor cell lines.

Shibuya N, Taki T, Mugishima H, Chin M, Tsuchida M, Sako M, Kawa K, Ishii E, Miura I, Yanagisawa M, Hayashi Y.

Genes Chromosomes Cancer. 2001 Sep;32(1):1-10.

PMID:
11477655
[PubMed - indexed for MEDLINE]
15.

Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression.

Dou L, Zheng D, Li J, Li Y, Gao L, Wang L, Yu L.

Oncogene. 2012 Jan 26;31(4):507-17. doi: 10.1038/onc.2011.248. Epub 2011 Jun 27.

PMID:
21706045
[PubMed - indexed for MEDLINE]
16.

Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.

Bizarro S, Cerveira N, Correia C, Lisboa S, Peixoto A, Norton L, Teixeira MR.

Cancer Genet Cytogenet. 2007 Oct 1;178(1):61-4.

PMID:
17889710
[PubMed - indexed for MEDLINE]
17.

A Novel t(4;11)(q21;q23) MLL-AF4 fusion transcript in infant leukemia.

Abdelhaleem M, Yi Q, Beimnet K, Grant R.

Am J Hematol. 2007 Mar;82(3):247. No abstract available.

PMID:
16924642
[PubMed - indexed for MEDLINE]
18.
19.

RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.

Wilkinson AC, Ballabio E, Geng H, North P, Tapia M, Kerry J, Biswas D, Roeder RG, Allis CD, Melnick A, de Bruijn MF, Milne TA.

Cell Rep. 2013 Jan 31;3(1):116-27. doi: 10.1016/j.celrep.2012.12.016. Epub 2013 Jan 24.

PMID:
23352661
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Simultaneous localization of MLL, AF4 and ENL genes in interphase nuclei by 3D-FISH: MLL translocation revisited.

Gué M, Sun JS, Boudier T.

BMC Cancer. 2006 Jan 24;6:20.

PMID:
16433901
[PubMed - indexed for MEDLINE]
Free PMC Article

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