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Items: 1 to 20 of 105


Mutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice.

Li J, Maruyama T, Zhang P, Konkel JE, Hoffman V, Zamarron B, Chen W.

Blood. 2010 Dec 16;116(25):5615-21. doi: 10.1182/blood-2010-03-274506. Epub 2010 Sep 17.


Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells.

Verykokakis M, Boos MD, Bendelac A, Adams EJ, Pereira P, Kee BL.

PLoS One. 2010 Feb 19;5(2):e9303. doi: 10.1371/journal.pone.0009303.


Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells.

Zhang B, Lin YY, Dai M, Zhuang Y.

J Immunol. 2014 Feb 1;192(3):1055-63. doi: 10.4049/jimmunol.1302694. Epub 2013 Dec 30.


Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis.

Ueda-Hayakawa I, Mahlios J, Zhuang Y.

J Immunol. 2009 May 1;182(9):5306-16. doi: 10.4049/jimmunol.0804249.


Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.

Lauritsen JP, Wong GW, Lee SY, Lefebvre JM, Ciofani M, Rhodes M, Kappes DJ, Zúñiga-Pflücker JC, Wiest DL.

Immunity. 2009 Oct 16;31(4):565-75. doi: 10.1016/j.immuni.2009.07.010.


Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.

Blom B, Heemskerk MH, Verschuren MC, van Dongen JJ, Stegmann AP, Bakker AQ, Couwenberg F, Res PC, Spits H.

EMBO J. 1999 May 17;18(10):2793-802.


αβ versus γδ fate choice: counting the T-cell lineages at the branch point.

Kreslavsky T, Gleimer M, Garbe AI, von Boehmer H.

Immunol Rev. 2010 Nov;238(1):169-81. doi: 10.1111/j.1600-065X.2010.00947.x. Review.


Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice.

Feng N, Vegh P, Rothenberg EV, Yui MA.

J Immunol. 2011 Jan 15;186(2):826-37. doi: 10.4049/jimmunol.1002630. Epub 2010 Dec 10.


Purinergic P2X7 receptor drives T cell lineage choice and shapes peripheral γδ cells.

Frascoli M, Marcandalli J, Schenk U, Grassi F.

J Immunol. 2012 Jul 1;189(1):174-80. doi: 10.4049/jimmunol.1101582. Epub 2012 May 30.


The inter-relatedness and interdependence of mouse T cell receptor gammadelta+ and alphabeta+ cells.

Pennington DJ, Silva-Santos B, Shires J, Theodoridis E, Pollitt C, Wise EL, Tigelaar RE, Owen MJ, Hayday AC.

Nat Immunol. 2003 Oct;4(10):991-8. Epub 2003 Sep 21.


Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansion.

Li J, Wu D, Jiang N, Zhuang Y.

J Immunol. 2013 Nov 15;191(10):5052-64. doi: 10.4049/jimmunol.1301252. Epub 2013 Oct 11.


Hepatosplenic alphabeta T-cell lymphomas: a report of 14 cases and comparison with hepatosplenic gammadelta T-cell lymphomas.

Macon WR, Levy NB, Kurtin PJ, Salhany KE, Elkhalifa MY, Casey TT, Craig FE, Vnencak-Jones CL, Gulley ML, Park JP, Cousar JB.

Am J Surg Pathol. 2001 Mar;25(3):285-96.


Phenotypic and functional maturation of TCR gammadelta cells in the human thymus.

Offner F, Van Beneden K, Debacker V, Vanhecke D, Vandekerckhove B, Plum J, Leclercq G.

J Immunol. 1997 May 15;158(10):4634-41.


The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.

Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, Rodewald HR, Saito R, Chang AN, Varki N, Kawamoto H, Murre C.

Genes Dev. 2015 Feb 15;29(4):409-25. doi: 10.1101/gad.255331.114.

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