Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 102

1.

Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D.

Nature. 2010 Sep 9;467(7312):179-84. doi: 10.1038/nature09299.

PMID:
20829789
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes.

Lee MJ, Lee BH, Hanna J, King RW, Finley D.

Mol Cell Proteomics. 2011 May;10(5):R110.003871. doi: 10.1074/mcp.R110.003871. Epub 2010 Sep 7. Review.

PMID:
20823120
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging.

Ponnappan S, Palmieri M, Sullivan DH, Ponnappan U.

Mech Ageing Dev. 2013 Jan-Feb;134(1-2):53-9. doi: 10.1016/j.mad.2012.12.007. Epub 2013 Jan 3.

PMID:
23291607
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity.

Walters BJ, Campbell SL, Chen PC, Taylor AP, Schroeder DG, Dobrunz LE, Artavanis-Tsakonas K, Ploegh HL, Wilson JA, Cox GA, Wilson SM.

Mol Cell Neurosci. 2008 Dec;39(4):539-48. doi: 10.1016/j.mcn.2008.07.028. Epub 2008 Aug 15.

PMID:
18771733
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction.

Vaden JH, Bhattacharyya BJ, Chen PC, Watson JA, Marshall AG, Phillips SE, Wilson JA, King GD, Miller RJ, Wilson SM.

Mol Neurodegener. 2015 Jan 10;10(1):3. [Epub ahead of print]

PMID:
25575639
[PubMed - as supplied by publisher]
Free Article
6.

Overexpression of USP14 protease reduces I-κB protein levels and increases cytokine release in lung epithelial cells.

Mialki RK, Zhao J, Wei J, Mallampalli DF, Zhao Y.

J Biol Chem. 2013 May 31;288(22):15437-41. doi: 10.1074/jbc.C112.446682. Epub 2013 Apr 24.

PMID:
23615914
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

D'Arcy P, Brnjic S, Olofsson MH, Fryknäs M, Lindsten K, De Cesare M, Perego P, Sadeghi B, Hassan M, Larsson R, Linder S.

Nat Med. 2011 Nov 6;17(12):1636-40. doi: 10.1038/nm.2536.

PMID:
22057347
[PubMed - indexed for MEDLINE]
8.

A High-Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14.

Lee BH, Finley D, King RW.

Curr Protoc Chem Biol. 2012 Dec 1;4(4):311-30. doi: 10.1002/9780470559277.ch120078.

PMID:
23788557
[PubMed]
Free PMC Article
9.

Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice.

Anderson C, Crimmins S, Wilson JA, Korbel GA, Ploegh HL, Wilson SM.

J Neurochem. 2005 Nov;95(3):724-31. Epub 2005 Sep 29.

PMID:
16190881
[PubMed - indexed for MEDLINE]
10.

The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions.

Chen PC, Qin LN, Li XM, Walters BJ, Wilson JA, Mei L, Wilson SM.

J Neurosci. 2009 Sep 2;29(35):10909-19. doi: 10.1523/JNEUROSCI.2635-09.2009.

PMID:
19726649
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening.

Peth A, Besche HC, Goldberg AL.

Mol Cell. 2009 Dec 11;36(5):794-804. doi: 10.1016/j.molcel.2009.11.015.

PMID:
20005843
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: implications for neurodegenerative diseases.

Seiberlich V, Goldbaum O, Zhukareva V, Richter-Landsberg C.

Biochim Biophys Acta. 2012 Nov;1823(11):2057-68. doi: 10.1016/j.bbamcr.2012.04.011. Epub 2012 Apr 28.

PMID:
22565157
[PubMed - indexed for MEDLINE]
Free Article
13.

A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short-term plasticity and vesicle number.

Walters BJ, Hallengren JJ, Theile CS, Ploegh HL, Wilson SM, Dobrunz LE.

J Physiol. 2014 Feb 15;592(Pt 4):571-86. doi: 10.1113/jphysiol.2013.266015. Epub 2013 Nov 11.

PMID:
24218545
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Deubiquitinating enzymes are IN/(trinsic to proteasome function).

Guterman A, Glickman MH.

Curr Protein Pept Sci. 2004 Jun;5(3):201-11. Review.

PMID:
15188770
[PubMed - indexed for MEDLINE]
15.

Role of the ubiquitin-proteasome system in brain ischemia: friend or foe?

Caldeira MV, Salazar IL, Curcio M, Canzoniero LM, Duarte CB.

Prog Neurobiol. 2014 Jan;112:50-69. doi: 10.1016/j.pneurobio.2013.10.003. Epub 2013 Oct 22. Review.

PMID:
24157661
[PubMed - indexed for MEDLINE]
16.

A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication.

Nag DK, Finley D.

Virus Res. 2012 Apr;165(1):103-6. doi: 10.1016/j.virusres.2012.01.009. Epub 2012 Jan 26.

PMID:
22306365
[PubMed - indexed for MEDLINE]
17.

Ubiquitinated proteins activate the proteasomal ATPases by binding to Usp14 or Uch37 homologs.

Peth A, Kukushkin N, Bossé M, Goldberg AL.

J Biol Chem. 2013 Mar 15;288(11):7781-90. doi: 10.1074/jbc.M112.441907. Epub 2013 Jan 22.

PMID:
23341450
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits.

Jin YN, Chen PC, Watson JA, Walters BJ, Phillips SE, Green K, Schmidt R, Wilson JA, Johnson GV, Roberson ED, Dobrunz LE, Wilson SM.

PLoS One. 2012;7(10):e47884. doi: 10.1371/journal.pone.0047884. Epub 2012 Oct 29.

PMID:
23144711
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14.

Crimmins S, Jin Y, Wheeler C, Huffman AK, Chapman C, Dobrunz LE, Levey A, Roth KA, Wilson JA, Wilson SM.

J Neurosci. 2006 Nov 1;26(44):11423-31.

PMID:
17079671
[PubMed - indexed for MEDLINE]
Free Article
20.

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

Besche HC, Sha Z, Kukushkin NV, Peth A, Hock EM, Kim W, Gygi S, Gutierrez JA, Liao H, Dick L, Goldberg AL.

EMBO J. 2014 May 16;33(10):1159-76. doi: 10.1002/embj.201386906. Epub 2014 May 8.

PMID:
24811749
[PubMed - indexed for MEDLINE]
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk