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Items: 1 to 20 of 171

1.

Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.

Shveygert M, Kaiser C, Bradrick SS, Gromeier M.

Mol Cell Biol. 2010 Nov;30(21):5160-7. doi: 10.1128/MCB.00448-10. Epub 2010 Sep 7.

2.

Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.

Korneeva NL, Song A, Gram H, Edens MA, Rhoads RE.

J Biol Chem. 2016 Feb 12;291(7):3455-67. doi: 10.1074/jbc.M115.694190. Epub 2015 Dec 14.

PMID:
26668315
3.

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo.

Waskiewicz AJ, Johnson JC, Penn B, Mahalingam M, Kimball SR, Cooper JA.

Mol Cell Biol. 1999 Mar;19(3):1871-80.

4.

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

Pyronnet S, Imataka H, Gingras AC, Fukunaga R, Hunter T, Sonenberg N.

EMBO J. 1999 Jan 4;18(1):270-9.

5.

Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk.

Orton KC, Ling J, Waskiewicz AJ, Cooper JA, Merrick WC, Korneeva NL, Rhoads RE, Sonenberg N, Traugh JA.

J Biol Chem. 2004 Sep 10;279(37):38649-57. Epub 2004 Jul 2.

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The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo.

Parra-Palau JL, Scheper GC, Harper DE, Proud CG.

Biochem J. 2005 Feb 1;385(Pt 3):695-702.

10.

Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1.

Dobrikov M, Dobrikova E, Shveygert M, Gromeier M.

Mol Cell Biol. 2011 Jul;31(14):2947-59. doi: 10.1128/MCB.05589-11. Epub 2011 May 16.

11.

Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling.

Parra-Palau JL, Scheper GC, Wilson ML, Proud CG.

J Biol Chem. 2003 Nov 7;278(45):44197-204. Epub 2003 Aug 28.

12.

Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1.

Pyronnet S.

Biochem Pharmacol. 2000 Oct 15;60(8):1237-43. Review.

PMID:
11007962
13.

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.

Waskiewicz AJ, Flynn A, Proud CG, Cooper JA.

EMBO J. 1997 Apr 15;16(8):1909-20.

14.

Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases.

Konicek BW, Stephens JR, McNulty AM, Robichaud N, Peery RB, Dumstorf CA, Dowless MS, Iversen PW, Parsons S, Ellis KE, McCann DJ, Pelletier J, Furic L, Yingling JM, Stancato LF, Sonenberg N, Graff JR.

Cancer Res. 2011 Mar 1;71(5):1849-57. doi: 10.1158/0008-5472.CAN-10-3298. Epub 2011 Jan 13.

15.

Roles of mitogen-activated protein kinase signal-integrating kinases 1 and 2 in oxidant-mediated eIF4E phosphorylation.

Shenberger JS, Zhang L, Hughlock MK, Ueda T, Watanabe-Fukunaga R, Fukunaga R.

Int J Biochem Cell Biol. 2007;39(10):1828-42. Epub 2007 May 10.

16.

The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization.

Scheper GC, Parra JL, Wilson M, Van Kollenburg B, Vertegaal AC, Han ZG, Proud CG.

Mol Cell Biol. 2003 Aug;23(16):5692-705.

17.

Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.

Wang X, Yue P, Chan CB, Ye K, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Fu H, Khuri FR, Sun SY.

Mol Cell Biol. 2007 Nov;27(21):7405-13. Epub 2007 Aug 27.

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19.

TGFβ-induced PI 3 kinase-dependent Mnk-1 activation is necessary for Ser-209 phosphorylation of eIF4E and mesangial cell hypertrophy.

Das F, Ghosh-Choudhury N, Bera A, Kasinath BS, Choudhury GG.

J Cell Physiol. 2013 Jul;228(7):1617-26. doi: 10.1002/jcp.24327.

20.

The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways.

Wang X, Flynn A, Waskiewicz AJ, Webb BL, Vries RG, Baines IA, Cooper JA, Proud CG.

J Biol Chem. 1998 Apr 17;273(16):9373-7.

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