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Results: 1 to 20 of 102

1.

Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma.

Lajoie S, Lewkowich IP, Suzuki Y, Clark JR, Sproles AA, Dienger K, Budelsky AL, Wills-Karp M.

Nat Immunol. 2010 Oct;11(10):928-35. doi: 10.1038/ni.1926. Epub 2010 Aug 29.

PMID:
20802484
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Diesel exhaust particle induction of IL-17A contributes to severe asthma.

Brandt EB, Kovacic MB, Lee GB, Gibson AM, Acciani TH, Le Cras TD, Ryan PH, Budelsky AL, Khurana Hershey GK.

J Allergy Clin Immunol. 2013 Nov;132(5):1194-1204.e2. doi: 10.1016/j.jaci.2013.06.048. Epub 2013 Sep 20.

PMID:
24060272
[PubMed - indexed for MEDLINE]
3.

Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis.

Bosmann M, Sarma JV, Atefi G, Zetoune FS, Ward PA.

FASEB J. 2012 Apr;26(4):1640-51. doi: 10.1096/fj.11-199216. Epub 2011 Dec 27.

PMID:
22202675
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation.

Baelder R, Fuchs B, Bautsch W, Zwirner J, Köhl J, Hoymann HG, Glaab T, Erpenbeck V, Krug N, Braun A.

J Immunol. 2005 Jan 15;174(2):783-9.

PMID:
15634899
[PubMed - indexed for MEDLINE]
Free Article
5.

Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice.

Lewkowich IP, Lajoie S, Clark JR, Herman NS, Sproles AA, Wills-Karp M.

PLoS One. 2008;3(12):e3879. doi: 10.1371/journal.pone.0003879. Epub 2008 Dec 8.

PMID:
19060952
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy.

Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA.

J Immunol. 2002 Nov 15;169(10):5926-33.

PMID:
12421977
[PubMed - indexed for MEDLINE]
Free Article
7.

Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.

Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ.

J Allergy Clin Immunol. 2013 Feb;131(2):541-8.e1-9. doi: 10.1016/j.jaci.2012.05.009. Epub 2012 Jun 22.

PMID:
22728083
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production.

Liu J, Lin F, Strainic MG, An F, Miller RH, Altuntas CZ, Heeger PS, Tuohy VK, Medof ME.

J Immunol. 2008 May 1;180(9):5882-9.

PMID:
18424707
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.

Köhl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M.

J Clin Invest. 2006 Mar;116(3):783-96.

PMID:
16511606
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A critical role for C5L2 in the pathogenesis of experimental allergic asthma.

Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, König P, Gerard NP, Gerard C, Wills-Karp M, Köhl J.

J Immunol. 2010 Dec 1;185(11):6741-52. doi: 10.4049/jimmunol.1000892. Epub 2010 Oct 25.

PMID:
20974988
[PubMed - indexed for MEDLINE]
Free Article
11.

IL-17A promotes the exacerbation of IL-33-induced airway hyperresponsiveness by enhancing neutrophilic inflammation via CXCR2 signaling in mice.

Mizutani N, Nabe T, Yoshino S.

J Immunol. 2014 Feb 15;192(4):1372-84. doi: 10.4049/jimmunol.1301538. Epub 2014 Jan 20.

PMID:
24446518
[PubMed - indexed for MEDLINE]
12.

A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells.

Zhang X, Lewkowich IP, Köhl G, Clark JR, Wills-Karp M, Köhl J.

J Immunol. 2009 Apr 15;182(8):5123-30. doi: 10.4049/jimmunol.0804276.

PMID:
19342693
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a.

Ali H.

Immunol Lett. 2010 Jan 18;128(1):36-45. doi: 10.1016/j.imlet.2009.10.007. Epub 2009 Nov 4. Review.

PMID:
19895849
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity.

Barlow JL, Flynn RJ, Ballantyne SJ, McKenzie AN.

Clin Exp Allergy. 2011 Oct;41(10):1447-55. doi: 10.1111/j.1365-2222.2011.03806.x. Epub 2011 Jul 4.

PMID:
21722219
[PubMed - indexed for MEDLINE]
15.

C5a receptor signalling in dendritic cells controls the development of maladaptive Th2 and Th17 immunity in experimental allergic asthma.

Schmudde I, Ströver HA, Vollbrandt T, König P, Karsten CM, Laumonnier Y, Köhl J.

Mucosal Immunol. 2013 Jul;6(4):807-25. doi: 10.1038/mi.2012.119. Epub 2012 Dec 5.

PMID:
23212198
[PubMed - indexed for MEDLINE]
16.

Complement C3a-induced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice.

Mizutani N, Goshima H, Nabe T, Yoshino S.

J Immunol. 2012 Jun 1;188(11):5694-705. doi: 10.4049/jimmunol.1103176. Epub 2012 Apr 25.

PMID:
22539791
[PubMed - indexed for MEDLINE]
Free Article
17.

The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen.

Kawamoto S, Yalcindag A, Laouini D, Brodeur S, Bryce P, Lu B, Humbles AA, Oettgen H, Gerard C, Geha RS.

J Clin Invest. 2004 Aug;114(3):399-407.

PMID:
15286806
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Negative regulation of pulmonary Th17 responses by C3a anaphylatoxin during allergic inflammation in mice.

Lim H, Kim YU, Drouin SM, Mueller-Ortiz S, Yun K, Morschl E, Wetsel RA, Chung Y.

PLoS One. 2012;7(12):e52666. doi: 10.1371/journal.pone.0052666. Epub 2012 Dec 20.

PMID:
23285141
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma.

Kirstein F, Horsnell WG, Kuperman DA, Huang X, Erle DJ, Lopata AL, Brombacher F.

J Allergy Clin Immunol. 2010 Aug;126(2):347-54. doi: 10.1016/j.jaci.2010.04.028. Epub 2010 Jun 25.

PMID:
20579713
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma.

Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, Köhl J, Wahl L, Kuperman D, Germer S, Aud D, Peltz G, Wills-Karp M.

Nat Immunol. 2000 Sep;1(3):221-6.

PMID:
10973279
[PubMed - indexed for MEDLINE]

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