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Results: 1 to 20 of 102

1.

Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domain.

Lamason RL, McCully RR, Lew SM, Pomerantz JL.

Biochemistry. 2010 Sep 28;49(38):8240-50. doi: 10.1021/bi101052d.

PMID:
20799731
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival.

Chan W, Schaffer TB, Pomerantz JL.

Mol Cell Biol. 2013 Jan;33(2):429-43. doi: 10.1128/MCB.00850-12. Epub 2012 Nov 12.

PMID:
23149938
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma.

Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Chan WC, Staudt LM.

Science. 2008 Mar 21;319(5870):1676-9. doi: 10.1126/science.1153629. Epub 2008 Mar 6.

PMID:
18323416
[PubMed - indexed for MEDLINE]
Free Article
5.

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.

Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S.

Science. 2005 Apr 1;308(5718):114-8.

PMID:
15802604
[PubMed - indexed for MEDLINE]
Free Article
6.

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.

Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, Staudt LM, Lenardo MJ.

Nature. 2009 Mar 5;458(7234):92-6. doi: 10.1038/nature07613. Epub 2008 Dec 31.

PMID:
19118383
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mutations of CARD11 but not TNFAIP3 may activate the NF-kappaB pathway in primary CNS lymphoma.

Montesinos-Rongen M, Schmitz R, Brunn A, Gesk S, Richter J, Hong K, Wiestler OD, Siebert R, Küppers R, Deckert M.

Acta Neuropathol. 2010 Oct;120(4):529-35. doi: 10.1007/s00401-010-0709-7. Epub 2010 Jun 11.

PMID:
20544211
[PubMed - indexed for MEDLINE]
8.

Role of nuclear factor-κB regulators TNFAIP3 and CARD11 in Middle Eastern diffuse large B-cell lymphoma.

Bu R, Bavi P, Abubaker J, Jehan Z, Al-Haqawi W, Ajarim D, Al-Dayel F, Uddin S, Al-Kuraya KS.

Leuk Lymphoma. 2012 Oct;53(10):1971-7. doi: 10.3109/10428194.2012.668286. Epub 2012 Apr 18.

PMID:
22397314
[PubMed - indexed for MEDLINE]
9.

Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma.

Qu C, Liu Y, Kunkalla K, Singh RR, Blonska M, Lin X, Agarwal NK, Vega F.

Blood. 2013 Jun 6;121(23):4718-28. doi: 10.1182/blood-2012-12-470153. Epub 2013 Apr 30.

PMID:
23632891
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.

Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM, Campo E, Jaffe ES, Wilson WH, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pierce SK, Staudt LM.

Nature. 2010 Jan 7;463(7277):88-92. doi: 10.1038/nature08638.

PMID:
20054396
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.

Pomerantz JL, Denny EM, Baltimore D.

EMBO J. 2002 Oct 1;21(19):5184-94.

PMID:
12356734
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.

Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES.

J Biol Chem. 2001 Apr 13;276(15):11877-82. Epub 2001 Jan 12.

PMID:
11278692
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells.

Ferch U, Kloo B, Gewies A, Pfänder V, Düwel M, Peschel C, Krappmann D, Ruland J.

J Exp Med. 2009 Oct 26;206(11):2313-20. doi: 10.1084/jem.20091167. Epub 2009 Oct 19. Erratum in: J Exp Med. 2009 Nov 23;206(12):2851.

PMID:
19841089
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.

Dong G, Chanudet E, Zeng N, Appert A, Chen YW, Au WY, Hamoudi RA, Watkins AJ, Ye H, Liu H, Gao Z, Chuang SS, Srivastava G, Du MQ.

Clin Cancer Res. 2011 Mar 15;17(6):1440-51. doi: 10.1158/1078-0432.CCR-10-1859. Epub 2011 Jan 25.

PMID:
21266526
[PubMed - indexed for MEDLINE]
Free Article
15.

Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas.

Naylor TL, Tang H, Ratsch BA, Enns A, Loo A, Chen L, Lenz P, Waters NJ, Schuler W, Dörken B, Yao YM, Warmuth M, Lenz G, Stegmeier F.

Cancer Res. 2011 Apr 1;71(7):2643-53. doi: 10.1158/0008-5472.CAN-10-2525. Epub 2011 Feb 15.

PMID:
21324920
[PubMed - indexed for MEDLINE]
Free Article
16.

Molecular pathways: targeting MALT1 paracaspase activity in lymphoma.

Fontán L, Melnick A.

Clin Cancer Res. 2013 Dec 15;19(24):6662-8. doi: 10.1158/1078-0432.CCR-12-3869. Epub 2013 Sep 4. Review.

PMID:
24004675
[PubMed - indexed for MEDLINE]
17.

The dynamic distribution of CARD11 at the immunological synapse is regulated by the inhibitory kinesin GAKIN.

Lamason RL, Kupfer A, Pomerantz JL.

Mol Cell. 2010 Dec 10;40(5):798-809. doi: 10.1016/j.molcel.2010.11.007.

PMID:
21145487
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosome.

Liu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB.

J Biol Chem. 2012 Jun 8;287(24):20081-7. doi: 10.1074/jbc.M111.335463. Epub 2012 Apr 23.

PMID:
22528498
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation.

Moreno-García ME, Sommer K, Rincon-Arano H, Brault M, Ninomiya-Tsuji J, Matesic LE, Rawlings DJ.

Mol Cell Biol. 2013 Mar;33(6):1149-63. doi: 10.1128/MCB.06407-11. Epub 2013 Jan 7.

PMID:
23297344
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Congenital B cell lymphocytosis explained by novel germline CARD11 mutations.

Snow AL, Xiao W, Stinson JR, Lu W, Chaigne-Delalande B, Zheng L, Pittaluga S, Matthews HF, Schmitz R, Jhavar S, Kuchen S, Kardava L, Wang W, Lamborn IT, Jing H, Raffeld M, Moir S, Fleisher TA, Staudt LM, Su HC, Lenardo MJ.

J Exp Med. 2012 Nov 19;209(12):2247-61. doi: 10.1084/jem.20120831. Epub 2012 Nov 5.

PMID:
23129749
[PubMed - indexed for MEDLINE]
Free PMC Article

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