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Results: 1 to 20 of 101

1.

Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis .

Parsonage D, Newton GL, Holder RC, Wallace BD, Paige C, Hamilton CJ, Dos Santos PC, Redinbo MR, Reid SD, Claiborne A.

Biochemistry. 2010 Sep 28;49(38):8398-414. doi: 10.1021/bi100698n.

PMID:
20799687
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.

Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6482-6. doi: 10.1073/pnas.1000928107. Epub 2010 Mar 22.

PMID:
20308541
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis.

Upton H, Newton GL, Gushiken M, Lo K, Holden D, Fahey RC, Rawat M.

FEBS Lett. 2012 Apr 5;586(7):1004-8. doi: 10.1016/j.febslet.2012.02.028. Epub 2012 Mar 6.

PMID:
22569254
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Bacillithiol, a new player in bacterial redox homeostasis.

Helmann JD.

Antioxid Redox Signal. 2011 Jul 1;15(1):123-33. doi: 10.1089/ars.2010.3562. Epub 2010 Dec 17. Review.

PMID:
20712413
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Detoxification of toxins by bacillithiol in Staphylococcus aureus.

Newton GL, Fahey RC, Rawat M.

Microbiology. 2012 Apr;158(Pt 4):1117-26. doi: 10.1099/mic.0.055715-0. Epub 2012 Jan 19. Erratum in: Microbiology. 2012 Sep;158(Pt 9):2450.

PMID:
22262099
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus.

Rajkarnikar A, Strankman A, Duran S, Vargas D, Roberts AA, Barretto K, Upton H, Hamilton CJ, Rawat M.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):128-33. doi: 10.1016/j.bbrc.2013.04.027. Epub 2013 Apr 22.

PMID:
23618856
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis.

Deli A, Koutsioulis D, Fadouloglou VE, Spiliotopoulou P, Balomenou S, Arnaouteli S, Tzanodaskalaki M, Mavromatis K, Kokkinidis M, Bouriotis V.

FEBS J. 2010 Jul;277(13):2740-53. doi: 10.1111/j.1742-4658.2010.07691.x. Epub 2010 May 19.

PMID:
20491912
[PubMed - indexed for MEDLINE]
8.

Cross-functionalities of Bacillus deacetylases involved in bacillithiol biosynthesis and bacillithiol-S-conjugate detoxification pathways.

Fang Z, Roberts AA, Weidman K, Sharma SV, Claiborne A, Hamilton CJ, Dos Santos PC.

Biochem J. 2013 Sep 1;454(2):239-47. doi: 10.1042/BJ20130415.

PMID:
23758290
[PubMed - indexed for MEDLINE]
Free Article
9.

Biochemistry of the initial steps of mycothiol biosynthesis.

Newton GL, Ta P, Bzymek KP, Fahey RC.

J Biol Chem. 2006 Nov 10;281(45):33910-20. Epub 2006 Aug 28.

PMID:
16940050
[PubMed - indexed for MEDLINE]
Free Article
10.

Distribution and infection-related functions of bacillithiol in Staphylococcus aureus.

Pöther DC, Gierok P, Harms M, Mostertz J, Hochgräfe F, Antelmann H, Hamilton CJ, Borovok I, Lalk M, Aharonowitz Y, Hecker M.

Int J Med Microbiol. 2013 Apr;303(3):114-23. doi: 10.1016/j.ijmm.2013.01.003. Epub 2013 Mar 6.

PMID:
23517692
[PubMed - indexed for MEDLINE]
11.

Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus.

Posada AC, Kolar SL, Dusi RG, Francois P, Roberts AA, Hamilton CJ, Liu GY, Cheung A.

Infect Immun. 2014 Jan;82(1):316-32. doi: 10.1128/IAI.01074-13. Epub 2013 Oct 28.

PMID:
24166956
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mechanistic studies of FosB: a divalent-metal-dependent bacillithiol-S-transferase that mediates fosfomycin resistance in Staphylococcus aureus.

Roberts AA, Sharma SV, Strankman AW, Duran SR, Rawat M, Hamilton CJ.

Biochem J. 2013 Apr 1;451(1):69-79. doi: 10.1042/BJ20121541.

PMID:
23256780
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria.

Newton GL, Buchmeier N, Fahey RC.

Microbiol Mol Biol Rev. 2008 Sep;72(3):471-94. doi: 10.1128/MMBR.00008-08. Review.

PMID:
18772286
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

S-bacillithiolation protects against hypochlorite stress in Bacillus subtilis as revealed by transcriptomics and redox proteomics.

Chi BK, Gronau K, Mäder U, Hessling B, Becher D, Antelmann H.

Mol Cell Proteomics. 2011 Nov;10(11):M111.009506. doi: 10.1074/mcp.M111.009506. Epub 2011 Jul 11.

PMID:
21749987
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status.

Newton GL, Ta P, Fahey RC.

J Bacteriol. 2005 Nov;187(21):7309-16.

PMID:
16237013
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis.

Newton GL, Av-Gay Y, Fahey RC.

J Bacteriol. 2000 Dec;182(24):6958-63.

PMID:
11092856
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Bacillithiol is an antioxidant thiol produced in Bacilli.

Newton GL, Rawat M, La Clair JJ, Jothivasan VK, Budiarto T, Hamilton CJ, Claiborne A, Helmann JD, Fahey RC.

Nat Chem Biol. 2009 Sep;5(9):625-7. doi: 10.1038/nchembio.189. Epub 2009 Jul 5.

PMID:
19578333
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Solution conformations of mycothiol bimane, 1-D-GlcNAc-alpha-(1 --> 1)-D-myo-Ins and 1-D-GlcNAc-alpha-(1 --> 1)-L-myo-Ins.

Mahadevan J, Nicholas GM, Bewley CA.

J Org Chem. 2003 May 2;68(9):3380-6.

PMID:
12713335
[PubMed - indexed for MEDLINE]
19.

S-bacillithiolation protects conserved and essential proteins against hypochlorite stress in firmicutes bacteria.

Chi BK, Roberts AA, Huyen TT, Bäsell K, Becher D, Albrecht D, Hamilton CJ, Antelmann H.

Antioxid Redox Signal. 2013 Apr 10;18(11):1273-95. doi: 10.1089/ars.2012.4686. Epub 2012 Oct 18.

PMID:
22938038
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins.

Lamers AP, Keithly ME, Kim K, Cook PD, Stec DF, Hines KM, Sulikowski GA, Armstrong RN.

Org Lett. 2012 Oct 19;14(20):5207-9. doi: 10.1021/ol302327t. Epub 2012 Oct 3.

PMID:
23030527
[PubMed - indexed for MEDLINE]
Free PMC Article

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