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Results: 1 to 20 of 92

1.

Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent.

Puliyappadamba VT, Cheriyan VT, Thulasidasan AK, Bava SV, Vinod BS, Prabhu PR, Varghese R, Bevin A, Venugopal S, Anto RJ.

Mol Cancer. 2010 Aug 20;9:220. doi: 10.1186/1476-4598-9-220.

PMID:
20727180
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism.

Bava SV, Sreekanth CN, Thulasidasan AK, Anto NP, Cheriyan VT, Puliyappadamba VT, Menon SG, Ravichandran SD, Anto RJ.

Int J Biochem Cell Biol. 2011 Mar;43(3):331-41. doi: 10.1016/j.biocel.2010.09.011. Epub 2010 Sep 29.

PMID:
20883815
[PubMed - indexed for MEDLINE]
3.
4.

Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.

Nagata Y, Takahashi A, Ohnishi K, Ota I, Ohnishi T, Tojo T, Taniguchi S.

Int J Oncol. 2010 Oct;37(4):1001-10.

PMID:
20811722
[PubMed - indexed for MEDLINE]
5.

Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.

Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.

Mol Pharmacol. 2006 Jan;69(1):195-206. Epub 2005 Oct 11.

PMID:
16219905
[PubMed - indexed for MEDLINE]
Free Article
6.

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.

Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB.

Oncogene. 2001 Nov 15;20(52):7597-609.

PMID:
11753638
[PubMed - indexed for MEDLINE]
Free Article
7.

Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.

Watson JL, Greenshields A, Hill R, Hilchie A, Lee PW, Giacomantonio CA, Hoskin DW.

Mol Carcinog. 2010 Jan;49(1):13-24. doi: 10.1002/mc.20571.

PMID:
19676105
[PubMed - indexed for MEDLINE]
9.

Curcumin potentiates the antitumor effects of 5-FU in treatment of esophageal squamous carcinoma cells through downregulating the activation of NF-κB signaling pathway in vitro and in vivo.

Tian F, Fan T, Zhang Y, Jiang Y, Zhang X.

Acta Biochim Biophys Sin (Shanghai). 2012 Oct;44(10):847-55.

PMID:
23017833
[PubMed - indexed for MEDLINE]
10.

Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE.

Clin Cancer Res. 2005 Oct 15;11(20):7490-8.

PMID:
16243823
[PubMed - indexed for MEDLINE]
Free Article
12.

Molecular evidences for the chemosensitizing efficacy of liposomal curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.

Sreekanth CN, Bava SV, Sreekumar E, Anto RJ.

Oncogene. 2011 Jul 14;30(28):3139-52. doi: 10.1038/onc.2011.23. Epub 2011 Feb 14.

PMID:
21317920
[PubMed - indexed for MEDLINE]
13.

Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.

Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C.

Cancer Res. 2005 Aug 1;65(15):6601-11.

PMID:
16061640
[PubMed - indexed for MEDLINE]
Free Article
15.

Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization.

Bava SV, Puliappadamba VT, Deepti A, Nair A, Karunagaran D, Anto RJ.

J Biol Chem. 2005 Feb 25;280(8):6301-8. Epub 2004 Dec 7.

PMID:
15590651
[PubMed - indexed for MEDLINE]
Free Article
16.

An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells.

Chang GC, Yu CT, Tsai CH, Tsai JR, Chen JC, Wu CC, Wu WJ, Hsu SL.

Eur J Pharmacol. 2008 Dec 14;600(1-3):37-44. doi: 10.1016/j.ejphar.2008.10.024. Epub 2008 Oct 21.

PMID:
18973751
[PubMed - indexed for MEDLINE]
17.

Induction of apoptosis in human lung cancer cells by curcumin.

Radhakrishna Pillai G, Srivastava AS, Hassanein TI, Chauhan DP, Carrier E.

Cancer Lett. 2004 May 28;208(2):163-70.

PMID:
15142674
[PubMed - indexed for MEDLINE]
18.

P53 and p38 MAPK pathways are involved in MONCPT-induced cell cycle G2/M arrest in human non-small cell lung cancer A549.

Zhang C, Zhu H, Yang X, Lou J, Zhu D, Lu W, He Q, Yang B.

J Cancer Res Clin Oncol. 2010 Mar;136(3):437-45. doi: 10.1007/s00432-009-0674-5. Epub 2009 Sep 2.

PMID:
19727814
[PubMed - indexed for MEDLINE]
19.

Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.

Chittezhath M, Deep G, Singh RP, Agarwal C, Agarwal R.

Mol Cancer Ther. 2008 Jul;7(7):1817-26. doi: 10.1158/1535-7163.MCT-08-0256.

PMID:
18644994
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo.

Katiyar SK, Meeran SM, Katiyar N, Akhtar S.

Mol Carcinog. 2009 Jan;48(1):24-37. doi: 10.1002/mc.20453.

PMID:
18459128
[PubMed - indexed for MEDLINE]

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