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Items: 1 to 20 of 132

1.

ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.

Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C, Debnath J.

Cell. 2010 Aug 20;142(4):590-600. doi: 10.1016/j.cell.2010.07.018.

2.

The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.

Tanida I, Yamasaki M, Komatsu M, Ueno T.

Autophagy. 2012 Jan;8(1):88-97. doi: 10.4161/auto.8.1.18339. Epub 2012 Jan 1.

PMID:
22170151
3.

Vaccinia virus leads to ATG12–ATG3 conjugation and deficiency in autophagosome formation.

Moloughney JG, Monken CE, Tao H, Zhang H, Thomas JD, Lattime EC, Jin S.

Autophagy. 2011 Dec;7(12):1434-47.

4.

Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.

Shao Y, Gao Z, Feldman T, Jiang X.

Autophagy. 2007 Jan-Feb;3(1):10-6. Epub 2007 Jan 27.

PMID:
16963840
5.

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.

Otomo C, Metlagel Z, Takaesu G, Otomo T.

Nat Struct Mol Biol. 2013 Jan;20(1):59-66. doi: 10.1038/nsmb.2431. Epub 2012 Dec 2.

6.

Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12.

Metlagel Z, Otomo C, Takaesu G, Otomo T.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18844-9. doi: 10.1073/pnas.1314755110. Epub 2013 Nov 4.

7.

Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy.

Nakatogawa H.

Essays Biochem. 2013;55:39-50. doi: 10.1042/bse0550039. Review.

PMID:
24070470
8.

ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function.

Murrow L, Malhotra R, Debnath J.

Nat Cell Biol. 2015 Mar;17(3):300-10. doi: 10.1038/ncb3112. Epub 2015 Feb 16.

9.

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity.

Haller M, Hock AK, Giampazolias E, Oberst A, Green DR, Debnath J, Ryan KM, Vousden KH, Tait SW.

Autophagy. 2014;10(12):2269-78. doi: 10.4161/15548627.2014.981914.

10.

Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.

Taherbhoy AM, Tait SW, Kaiser SE, Williams AH, Deng A, Nourse A, Hammel M, Kurinov I, Rock CO, Green DR, Schulman BA.

Mol Cell. 2011 Nov 4;44(3):451-61. doi: 10.1016/j.molcel.2011.08.034.

11.

ATG12-ATG3 connects basal autophagy and late endosome function.

Murrow L, Debnath J.

Autophagy. 2015;11(6):961-2. doi: 10.1080/15548627.2015.1040976. Review.

12.

ATG12-ATG3 and mitochondria.

Radoshevich L, Debnath J.

Autophagy. 2011 Jan;7(1):109-11. Epub 2011 Jan 1. No abstract available.

13.

The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.

Sou YS, Waguri S, Iwata J, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanaka K, Komatsu M.

Mol Biol Cell. 2008 Nov;19(11):4762-75. doi: 10.1091/mbc.E08-03-0309. Epub 2008 Sep 3.

14.

Binding to E1 and E3 is mutually exclusive for the human autophagy E2 Atg3.

Qiu Y, Hofmann K, Coats JE, Schulman BA, Kaiser SE.

Protein Sci. 2013 Dec;22(12):1691-7. doi: 10.1002/pro.2381.

15.

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site.

Sakoh-Nakatogawa M, Matoba K, Asai E, Kirisako H, Ishii J, Noda NN, Inagaki F, Nakatogawa H, Ohsumi Y.

Nat Struct Mol Biol. 2013 Apr;20(4):433-9. doi: 10.1038/nsmb.2527. Epub 2013 Mar 17.

PMID:
23503366
16.

The Ubi brothers reunited.

Noda T, Fujita N, Yoshimori T.

Autophagy. 2008 May;4(4):540-1. Epub 2008 Mar 26.

PMID:
18398292
17.

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.

Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.

J Biol Chem. 2007 Dec 28;282(52):37298-302. Epub 2007 Nov 6.

18.

Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.

Yamaguchi M, Noda NN, Nakatogawa H, Kumeta H, Ohsumi Y, Inagaki F.

J Biol Chem. 2010 Sep 17;285(38):29599-607. doi: 10.1074/jbc.M110.113670. Epub 2010 Jul 8.

19.

Visualization of Atg3 during autophagosome formation in Saccharomyces cerevisiae.

Ngu M, Hirata E, Suzuki K.

J Biol Chem. 2015 Mar 27;290(13):8146-53. doi: 10.1074/jbc.M114.626952. Epub 2015 Feb 2.

20.

Structural insights into E2-E3 interaction for LC3 lipidation.

Metlagel Z, Otomo C, Ohashi K, Takaesu G, Otomo T.

Autophagy. 2014 Mar;10(3):522-3. doi: 10.4161/auto.27594. Epub 2014 Jan 9. Review.

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