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Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.

Morel C, Standen CL, Jung DY, Gray S, Ong H, Flavell RA, Kim JK, Davis RJ.

Mol Cell Biol. 2010 Oct;30(19):4616-25. doi: 10.1128/MCB.00585-10. Epub 2010 Aug 2.


Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.

Standen CL, Kennedy NJ, Flavell RA, Davis RJ.

Mol Cell Biol. 2009 Sep;29(17):4831-40. doi: 10.1128/MCB.00155-09. Epub 2009 Jun 29.


Requirement of the JIP1 scaffold protein for stress-induced JNK activation.

Whitmarsh AJ, Kuan CY, Kennedy NJ, Kelkar N, Haydar TF, Mordes JP, Appel M, Rossini AA, Jones SN, Flavell RA, Rakic P, Davis RJ.

Genes Dev. 2001 Sep 15;15(18):2421-32.


An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue.

Jaeschke A, Czech MP, Davis RJ.

Genes Dev. 2004 Aug 15;18(16):1976-80.


Protein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.

Panzhinskiy E, Ren J, Nair S.

PLoS One. 2013 Oct 18;8(10):e77228. doi: 10.1371/journal.pone.0077228. eCollection 2013.


Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.

Vaishnav M, MacFarlane M, Dickens M.

Exp Cell Res. 2011 Apr 15;317(7):1028-39. doi: 10.1016/j.yexcr.2011.01.011. Epub 2011 Jan 13.


Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.

Barnat M, Enslen H, Propst F, Davis RJ, Soares S, Nothias F.

J Neurosci. 2010 Jun 9;30(23):7804-16. doi: 10.1523/JNEUROSCI.0372-10.2010.


MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet.

Gadang V, Kohli R, Myronovych A, Hui DY, Perez-Tilve D, Jaeschke A.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E549-56. doi: 10.1152/ajpendo.00197.2013. Epub 2013 Jul 16.


The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM.

J Biol Chem. 2013 Jul 26;288(30):21729-41. doi: 10.1074/jbc.M113.463885. Epub 2013 Jun 14.


Pharmacological characterization of a small molecule inhibitor of c-Jun kinase.

Cho H, Black SC, Looper D, Shi M, Kelly-Sullivan D, Timofeevski S, Siegel K, Yu XH, McDonnell SR, Chen P, Yie J, Ogilvie KM, Fraser J, Briscoe CP.

Am J Physiol Endocrinol Metab. 2008 Nov;295(5):E1142-51. doi: 10.1152/ajpendo.90298.2008. Epub 2008 Aug 26.


Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.

Latreille M, Laberge MK, Bourret G, Yamani L, Larose L.

Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E423-34. doi: 10.1152/ajpendo.00088.2010. Epub 2010 Jun 29.


Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.

Pal M, Wunderlich CM, Spohn G, Brönneke HS, Schmidt-Supprian M, Wunderlich FT.

PLoS One. 2013;8(1):e54247. doi: 10.1371/journal.pone.0054247. Epub 2013 Jan 17.


Reassembly of JIP1 scaffold complex in JNK MAP kinase pathway using heterologous protein interactions.

Moon J, Park SH.

PLoS One. 2014 May 9;9(5):e96797. doi: 10.1371/journal.pone.0096797. eCollection 2014.


Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.

Xu B, Zhou Y, O K, Choy PC, Pierce GN, Siow YL.

Can J Physiol Pharmacol. 2010 Nov;88(11):1084-92. doi: 10.1139/y10-088.


Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway.

Kim JW, Kim MJ, Kim KJ, Yun HJ, Chae JS, Hwang SG, Chang TS, Park HS, Lee KW, Han PL, Cho SG, Kim TW, Choi EJ.

Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14308-13. Epub 2005 Sep 22.


JIP1 binding to RBP-Jk mediates cross-talk between the Notch1 and JIP1-JNK signaling pathway.

Kim MY, Ann EJ, Mo JS, Dajas-Bailador F, Seo MS, Hong JA, Jung J, Choi YH, Yoon JH, Kim SM, Choi EJ, Hoe HS, Whitmarsh AJ, Park HS.

Cell Death Differ. 2010 Nov;17(11):1728-38. doi: 10.1038/cdd.2010.50. Epub 2010 May 28.


JIP1 regulates neuronal apoptosis in response to stress.

Dong Z, Zhou L, Del Villar K, Ghanevati M, Tashjian V, Miller CA.

Brain Res Mol Brain Res. 2005 Apr 4;134(2):282-93.


Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice.

Im JY, Lee KW, Kim MH, Lee SH, Ha HY, Cho IH, Kim D, Yu MS, Kim JB, Lee JK, Kim YJ, Youn BW, Yang SD, Shin HS, Han PL.

J Neurosci Res. 2003 Oct 15;74(2):326-32.

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