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Results: 1 to 20 of 66

1.

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.

Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, Goutagny N, Kuang W, Askew GR, Roberts V, Benoit S, Zhou T, Ling V, Pfeifer R, Stedman N, Fitzgerald KA, Lin LL, Hall JP.

J Leukoc Biol. 2010 Dec;88(6):1171-80. doi: 10.1189/jlb.0210071. Epub 2010 Jul 22.

PMID:
20651301
[PubMed - indexed for MEDLINE]
Free Article
2.

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection.

Perry AK, Chow EK, Goodnough JB, Yeh WC, Cheng G.

J Exp Med. 2004 Jun 21;199(12):1651-8.

PMID:
15210743
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages.

Solis M, Romieu-Mourez R, Goubau D, Grandvaux N, Mesplede T, Julkunen I, Nardin A, Salcedo M, Hiscott J.

Eur J Immunol. 2007 Feb;37(2):528-39.

PMID:
17236232
[PubMed - indexed for MEDLINE]
4.

The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3.

Lee SH, Kim JS, Jun HK, Lee HR, Lee D, Choi BK.

J Immunol. 2009 May 1;182(9):5823-35. doi: 10.4049/jimmunol.0802765.

PMID:
19380831
[PubMed - indexed for MEDLINE]
Free Article
5.

Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.

Gabhann JN, Higgs R, Brennan K, Thomas W, Damen JE, Ben Larbi N, Krystal G, Jefferies CA.

J Immunol. 2010 Mar 1;184(5):2314-20. doi: 10.4049/jimmunol.0902589. Epub 2010 Jan 25.

PMID:
20100929
[PubMed - indexed for MEDLINE]
Free Article
6.

Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation.

McCoy CE, Carpenter S, Pålsson-McDermott EM, Gearing LJ, O'Neill LA.

J Biol Chem. 2008 May 23;283(21):14277-85. doi: 10.1074/jbc.M709731200. Epub 2008 Mar 20.

PMID:
18356163
[PubMed - indexed for MEDLINE]
Free Article
7.

Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.

Clark K, Plater L, Peggie M, Cohen P.

J Biol Chem. 2009 May 22;284(21):14136-46. doi: 10.1074/jbc.M109.000414. Epub 2009 Mar 22.

PMID:
19307177
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events.

Hambleton J, McMahon M, DeFranco AL.

J Exp Med. 1995 Jul 1;182(1):147-54.

PMID:
7790814
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.

An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X.

Immunity. 2006 Dec;25(6):919-28. Epub 2006 Dec 7.

PMID:
17157040
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Control of TANK-binding kinase 1-mediated signaling by the gamma(1)34.5 protein of herpes simplex virus 1.

Verpooten D, Ma Y, Hou S, Yan Z, He B.

J Biol Chem. 2009 Jan 9;284(2):1097-105. doi: 10.1074/jbc.M805905200. Epub 2008 Nov 14.

PMID:
19010780
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Decreased somatostatin is related to the hypersensitivity of intestinal epithelia to LPS via upregulated TLR4-TBK1 pathway in rats chronically exposed to ethanol.

Zhou C, Li J, Wang H, Tang C.

Alcohol. 2009 Jun;43(4):293-303. doi: 10.1016/j.alcohol.2009.03.002. Epub 2009 Apr 17.

PMID:
19375882
[PubMed - indexed for MEDLINE]
14.
15.

Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2.

Cuesta N, Salkowski CA, Thomas KE, Vogel SN.

J Immunol. 2003 Jun 1;170(11):5739-47.

PMID:
12759457
[PubMed - indexed for MEDLINE]
Free Article
16.

The resistance of P. acnes--primed interferon gamma-deficient mice to low-dose lipopolysaccharide-induced acute liver injury.

Shimizu Y, Margenthaler JA, Landeros K, Otomo N, Doherty G, Flye MW.

Hepatology. 2002 Apr;35(4):805-14.

PMID:
11915026
[PubMed - indexed for MEDLINE]
17.

MCP-1 expression in endotoxin-induced uveitis.

Tuaillon N, Shen DF, Berger RB, Lu B, Rollins BJ, Chan CC.

Invest Ophthalmol Vis Sci. 2002 May;43(5):1493-8.

PMID:
11980865
[PubMed - indexed for MEDLINE]
Free Article
18.

Microfilariae of the filarial nematode Litomosoides sigmodontis exacerbate the course of lipopolysaccharide-induced sepsis in mice.

Hübner MP, Pasche B, Kalaydjiev S, Soboslay PT, Lengeling A, Schulz-Key H, Mitre E, Hoffmann WH.

Infect Immun. 2008 Apr;76(4):1668-77. doi: 10.1128/IAI.01042-07. Epub 2008 Feb 4.

PMID:
18250172
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.

Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E.

J Virol. 2009 May;83(9):4081-91. doi: 10.1128/JVI.02591-08. Epub 2009 Feb 11.

PMID:
19211767
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

poly(I:C) and LPS induce distinct IRF3 and NF-kappaB signaling during type-I IFN and TNF responses in human macrophages.

Reimer T, Brcic M, Schweizer M, Jungi TW.

J Leukoc Biol. 2008 May;83(5):1249-57. doi: 10.1189/jlb.0607412. Epub 2008 Feb 5.

PMID:
18252870
[PubMed - indexed for MEDLINE]
Free Article

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