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Results: 1 to 20 of 128

1.

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.

Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME.

Ann Neurol. 2010 Aug;68(2):220-30. doi: 10.1002/ana.22052.

PMID:
20641005
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.

Melnikova T, Fromholt S, Kim H, Lee D, Xu G, Price A, Moore BD, Golde TE, Felsenstein KM, Savonenko A, Borchelt DR.

J Neurosci. 2013 Feb 27;33(9):3765-79. doi: 10.1523/JNEUROSCI.4251-12.2013.

PMID:
23447589
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
[PubMed - indexed for MEDLINE]
4.

Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.

Mori T, Rezai-Zadeh K, Koyama N, Arendash GW, Yamaguchi H, Kakuda N, Horikoshi-Sakuraba Y, Tan J, Town T.

J Biol Chem. 2012 Feb 24;287(9):6912-27. doi: 10.1074/jbc.M111.294025. Epub 2012 Jan 4.

PMID:
22219198
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques.

Koistinaho M, Ort M, Cimadevilla JM, Vondrous R, Cordell B, Koistinaho J, Bures J, Higgins LS.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14675-80. Epub 2001 Nov 27.

PMID:
11724968
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

[Effects of huannao yicong recipe extract on the learning and memory and related factors of Abeta generation in the brain of APP transgenic mice].

Li H, Liu MF, Liu JG, Liu LT, Guan J, Cai LL, Hu J, Wei Y.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jan;33(1):90-4. Chinese.

PMID:
23596795
[PubMed - indexed for MEDLINE]
7.

Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.

Lewis TL, Cao D, Lu H, Mans RA, Su YR, Jungbauer L, Linton MF, Fazio S, LaDu MJ, Li L.

J Biol Chem. 2010 Nov 19;285(47):36958-68. doi: 10.1074/jbc.M110.127829. Epub 2010 Sep 16.

PMID:
20847045
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.

Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J.

J Neurosci. 2005 Jul 20;25(29):6755-64.

PMID:
16033885
[PubMed - indexed for MEDLINE]
Free Article
9.

Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.

España J, Giménez-Llort L, Valero J, Miñano A, Rábano A, Rodriguez-Alvarez J, LaFerla FM, Saura CA.

Biol Psychiatry. 2010 Mar 15;67(6):513-21. doi: 10.1016/j.biopsych.2009.06.015. Epub 2009 Aug 7.

PMID:
19664757
[PubMed - indexed for MEDLINE]
10.

NSE-controlled carboxyl-terminus of APP gene over-expressing in transgenic mice induces altered expressions in behavior, Abeta-42, and GSK3beta binding proteins.

Lim HJ, Cho JS, Oh JH, Shim SB, Hwang DY, Jee SW, Lee SH, Sheen YY, Lee SH, Kim YK.

Cell Mol Neurobiol. 2005 Aug;25(5):833-50.

PMID:
16133937
[PubMed - indexed for MEDLINE]
11.

Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease.

Lok K, Zhao H, Zhang C, He N, Shen H, Wang Z, Zhao W, Yin M.

J Neurol Sci. 2013 Dec 15;335(1-2):145-54. doi: 10.1016/j.jns.2013.09.018. Epub 2013 Sep 21.

PMID:
24095271
[PubMed - indexed for MEDLINE]
12.

Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.

Fitz NF, Cronican AA, Saleem M, Fauq AH, Chapman R, Lefterov I, Koldamova R.

J Neurosci. 2012 Sep 19;32(38):13125-36.

PMID:
22993429
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.

Durairajan SS, Liu LF, Lu JH, Chen LL, Yuan Q, Chung SK, Huang L, Li XS, Huang JD, Li M.

Neurobiol Aging. 2012 Dec;33(12):2903-19. doi: 10.1016/j.neurobiolaging.2012.02.016. Epub 2012 Mar 27.

PMID:
22459600
[PubMed - indexed for MEDLINE]
14.

Normal cognition in transgenic BRI2-Aβ mice.

Kim J, Chakrabarty P, Hanna A, March A, Dickson DW, Borchelt DR, Golde T, Janus C.

Mol Neurodegener. 2013 May 12;8:15. doi: 10.1186/1750-1326-8-15.

PMID:
23663320
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.

Biochemistry. 1998 Nov 24;37(47):16465-71.

PMID:
9843412
[PubMed - indexed for MEDLINE]
16.

Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice.

Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R.

J Biol Chem. 2010 Nov 19;285(47):36945-57. doi: 10.1074/jbc.M110.127738. Epub 2010 Aug 25.

PMID:
20739292
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.

Peng Y, Sun J, Hon S, Nylander AN, Xia W, Feng Y, Wang X, Lemere CA.

J Neurosci. 2010 Jun 16;30(24):8180-9. doi: 10.1523/JNEUROSCI.0340-10.2010.

PMID:
20554868
[PubMed - indexed for MEDLINE]
Free Article
18.

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.

J Neurosci Res. 2006 May 15;83(7):1252-61.

PMID:
16511867
[PubMed - indexed for MEDLINE]
19.

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. doi: 10.1007/s00417-009-1060-3. Epub 2009 Mar 7.

PMID:
19271231
[PubMed - indexed for MEDLINE]
20.

Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice.

Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M, Riederer P, Hoyer S.

J Alzheimers Dis. 2010;19(2):691-704. doi: 10.3233/JAD-2010-1270.

PMID:
20110613
[PubMed - indexed for MEDLINE]

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