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Results: 1 to 20 of 101

1.

Regulation of notch1 signaling by nrf2: implications for tissue regeneration.

Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak MK, Misra V, Biswal S, Yamamoto M, Kensler TW.

Sci Signal. 2010 Jul 13;3(130):ra52. doi: 10.1126/scisignal.2000762.

PMID:
20628156
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

When NRF2 talks, who's listening?

Wakabayashi N, Slocum SL, Skoko JJ, Shin S, Kensler TW.

Antioxid Redox Signal. 2010 Dec 1;13(11):1649-63. doi: 10.1089/ars.2010.3216. Epub 2010 Jul 9. Review.

PMID:
20367496
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.

Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW.

Carcinogenesis. 2009 Jun;30(6):1024-31. doi: 10.1093/carcin/bgp100. Epub 2009 Apr 21.

PMID:
19386581
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

He X, Chen MG, Lin GX, Ma Q.

J Biol Chem. 2006 Aug 18;281(33):23620-31. Epub 2006 Jun 19.

PMID:
16785233
[PubMed - indexed for MEDLINE]
Free Article
5.

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.

Muthusamy VR, Kannan S, Sadhaasivam K, Gounder SS, Davidson CJ, Boeheme C, Hoidal JR, Wang L, Rajasekaran NS.

Free Radic Biol Med. 2012 Jan 15;52(2):366-76. doi: 10.1016/j.freeradbiomed.2011.10.440. Epub 2011 Oct 20.

PMID:
22051043
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis.

Kong X, Thimmulappa R, Craciun F, Harvey C, Singh A, Kombairaju P, Reddy SP, Remick D, Biswal S.

Am J Respir Crit Care Med. 2011 Oct 15;184(8):928-38. doi: 10.1164/rccm.201102-0271OC. Epub 2011 Jul 28.

PMID:
21799073
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway.

Kensler TW, Wakabayashi N, Biswal S.

Annu Rev Pharmacol Toxicol. 2007;47:89-116. Review.

PMID:
16968214
[PubMed - indexed for MEDLINE]
8.

Nrf2 protects against airway disorders.

Cho HY, Kleeberger SR.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):43-56. doi: 10.1016/j.taap.2009.07.024. Epub 2009 Jul 29. Review. Erratum in: Toxicol Appl Pharmacol. 2010 Aug 1;246(3):186-7.

PMID:
19646463
[PubMed - indexed for MEDLINE]
9.

Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis.

Hou Y, Xue P, Bai Y, Liu D, Woods CG, Yarborough K, Fu J, Zhang Q, Sun G, Collins S, Chan JY, Yamamoto M, Andersen ME, Pi J.

Free Radic Biol Med. 2012 Jan 15;52(2):462-72. doi: 10.1016/j.freeradbiomed.2011.10.453. Epub 2011 Oct 28.

PMID:
22138520
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.

Itoh K, Tong KI, Yamamoto M.

Free Radic Biol Med. 2004 May 15;36(10):1208-13. Review.

PMID:
15110385
[PubMed - indexed for MEDLINE]
11.

KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response.

Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD.

Mol Cell Biol. 2011 May;31(9):1800-11. doi: 10.1128/MCB.05036-11. Epub 2011 Mar 7.

PMID:
21383067
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle.

Miller CJ, Gounder SS, Kannan S, Goutam K, Muthusamy VR, Firpo MA, Symons JD, Paine R 3rd, Hoidal JR, Rajasekaran NS.

Biochim Biophys Acta. 2012 Jun;1822(6):1038-50. doi: 10.1016/j.bbadis.2012.02.007. Epub 2012 Feb 15.

PMID:
22366763
[PubMed - indexed for MEDLINE]
Free Article
13.

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress.

Nguyen T, Nioi P, Pickett CB.

J Biol Chem. 2009 May 15;284(20):13291-5. doi: 10.1074/jbc.R900010200. Epub 2009 Jan 30. Review.

PMID:
19182219
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2).

Li W, Liu H, Zhou JS, Cao JF, Zhou XB, Choi AM, Chen ZH, Shen HH.

J Biol Chem. 2012 Jun 15;287(25):20922-30. doi: 10.1074/jbc.M112.352336. Epub 2012 Apr 30.

PMID:
22547061
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.

Shin S, Wakabayashi N, Misra V, Biswal S, Lee GH, Agoston ES, Yamamoto M, Kensler TW.

Mol Cell Biol. 2007 Oct;27(20):7188-97. Epub 2007 Aug 20.

PMID:
17709388
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.

Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M.

Mol Cell Biol. 2014 Mar;34(5):900-13. doi: 10.1128/MCB.01384-13. Epub 2013 Dec 30.

PMID:
24379438
[PubMed - indexed for MEDLINE]
17.

Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.

Williamson TP, Johnson DA, Johnson JA.

Neurotoxicology. 2012 Jun;33(3):272-9. doi: 10.1016/j.neuro.2012.01.015. Epub 2012 Feb 9.

PMID:
22342405
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.

J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.

PMID:
20452972
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

New player on an old field; the keap1/Nrf2 pathway as a target for treatment of type 2 diabetes and metabolic syndrome.

Chartoumpekis DV, Kensler TW.

Curr Diabetes Rev. 2013 Mar 1;9(2):137-45. Review.

PMID:
23363332
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660
[PubMed - indexed for MEDLINE]

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