Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 122

1.

An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer.

Wasserman NF, Aneas I, Nobrega MA.

Genome Res. 2010 Sep;20(9):1191-7. doi: 10.1101/gr.105361.110. Epub 2010 Jul 13.

PMID:
20627891
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.

Salinas CA, Kwon E, Carlson CS, Koopmeiners JS, Feng Z, Karyadi DM, Ostrander EA, Stanford JL.

Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1203-13. doi: 10.1158/1055-9965.EPI-07-2811.

PMID:
18483343
[PubMed - indexed for MEDLINE]
Free Article
3.

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.

Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao K, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML.

Nat Genet. 2009 Aug;41(8):882-4. doi: 10.1038/ng.403. Epub 2009 Jun 28.

PMID:
19561607
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

Tuupanen S, Turunen M, Lehtonen R, Hallikas O, Vanharanta S, Kivioja T, Björklund M, Wei G, Yan J, Niittymäki I, Mecklin JP, Järvinen H, Ristimäki A, Di-Bernardo M, East P, Carvajal-Carmona L, Houlston RS, Tomlinson I, Palin K, Ukkonen E, Karhu A, Taipale J, Aaltonen LA.

Nat Genet. 2009 Aug;41(8):885-90. doi: 10.1038/ng.406. Epub 2009 Jun 28.

PMID:
19561604
[PubMed - indexed for MEDLINE]
5.

A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.

Meyer KB, Maia AT, O'Reilly M, Ghoussaini M, Prathalingam R, Porter-Gill P, Ambs S, Prokunina-Olsson L, Carroll J, Ponder BA.

PLoS Genet. 2011 Jul;7(7):e1002165. doi: 10.1371/journal.pgen.1002165. Epub 2011 Jul 21.

PMID:
21814516
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Long-range enhancers on 8q24 regulate c-Myc.

Sotelo J, Esposito D, Duhagon MA, Banfield K, Mehalko J, Liao H, Stephens RM, Harris TJ, Munroe DJ, Wu X.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3001-5. doi: 10.1073/pnas.0906067107. Epub 2010 Jan 26.

PMID:
20133699
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders.

Glinskii AB, Ma S, Ma J, Grant D, Lim CU, Guest I, Sell S, Buttyan R, Glinsky GV.

Cell Cycle. 2011 Oct 15;10(20):3571-97. doi: 10.4161/cc.10.20.17842.

PMID:
22067658
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

Sur IK, Hallikas O, Vähärautio A, Yan J, Turunen M, Enge M, Taipale M, Karhu A, Aaltonen LA, Taipale J.

Science. 2012 Dec 7;338(6112):1360-3. doi: 10.1126/science.1228606. Epub 2012 Nov 1.

PMID:
23118011
[PubMed - indexed for MEDLINE]
Free Article
9.

Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5.

Kim T, Cui R, Jeon YJ, Lee JH, Lee JH, Sim H, Park JK, Fadda P, Tili E, Nakanishi H, Huh MI, Kim SH, Cho JH, Sung BH, Peng Y, Lee TJ, Luo Z, Sun HL, Wei H, Alder H, Oh JS, Shim KS, Ko SB, Croce CM.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4173-8. doi: 10.1073/pnas.1400350111. Epub 2014 Mar 4.

PMID:
24594601
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells.

Wright JB, Brown SJ, Cole MD.

Mol Cell Biol. 2010 Mar;30(6):1411-20. doi: 10.1128/MCB.01384-09. Epub 2010 Jan 11.

PMID:
20065031
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus.

Zhang X, Cowper-Sal lari R, Bailey SD, Moore JH, Lupien M.

Genome Res. 2012 Aug;22(8):1437-46. doi: 10.1101/gr.135665.111. Epub 2012 Jun 4.

PMID:
22665440
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.

Ting MC, Liao CP, Yan C, Jia L, Groshen S, Frenkel B, Roy-Burman P, Coetzee GA, Maxson R.

Dis Model Mech. 2012 May;5(3):366-74. doi: 10.1242/dmm.008458. Epub 2012 Jan 25.

PMID:
22279083
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans.

Zheng SL, Sun J, Cheng Y, Li G, Hsu FC, Zhu Y, Chang BL, Liu W, Kim JW, Turner AR, Gielzak M, Yan G, Isaacs SD, Wiley KE, Sauvageot J, Chen HS, Gurganus R, Mangold LA, Trock BJ, Gronberg H, Duggan D, Carpten JD, Partin AW, Walsh PC, Xu J, Isaacs WB.

J Natl Cancer Inst. 2007 Oct 17;99(20):1525-33. Epub 2007 Oct 9.

PMID:
17925536
[PubMed - indexed for MEDLINE]
Free Article
14.

Common variants in 8q24 are associated with risk for prostate cancer and tumor aggressiveness in men of European ancestry.

Pal P, Xi H, Guha S, Sun G, Helfand BT, Meeks JJ, Suarez BK, Catalona WJ, Deka R.

Prostate. 2009 Oct 1;69(14):1548-56. doi: 10.1002/pros.20999.

PMID:
19562729
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Multiple loci with different cancer specificities within the 8q24 gene desert.

Ghoussaini M, Song H, Koessler T, Al Olama AA, Kote-Jarai Z, Driver KE, Pooley KA, Ramus SJ, Kjaer SK, Hogdall E, DiCioccio RA, Whittemore AS, Gayther SA, Giles GG, Guy M, Edwards SM, Morrison J, Donovan JL, Hamdy FC, Dearnaley DP, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Brown PM, Hopper JL, Neal DE, Pharoah PD, Ponder BA, Eeles RA, Easton DF, Dunning AM; UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology; UK ProtecT Study Collaborators.

J Natl Cancer Inst. 2008 Jul 2;100(13):962-6. doi: 10.1093/jnci/djn190. Epub 2008 Jun 24.

PMID:
18577746
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

In vivo exploration of the functional activity of the non-coding 8q24 prostate cancer risk locus.

Lamb DJ, Tannour-Louet M.

Asian J Androl. 2010 Nov;12(6):787-9. doi: 10.1038/aja.2010.102. Epub 2010 Sep 6. No abstract available.

PMID:
20818410
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.

Savic D, Bell GI, Nobrega MA.

PLoS One. 2012;7(5):e36501. doi: 10.1371/journal.pone.0036501. Epub 2012 May 10.

PMID:
22590553
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

8q24 and prostate cancer: association with advanced disease and meta-analysis.

Cheng I, Plummer SJ, Jorgenson E, Liu X, Rybicki BA, Casey G, Witte JS.

Eur J Hum Genet. 2008 Apr;16(4):496-505. doi: 10.1038/sj.ejhg.5201959. Epub 2008 Jan 30.

PMID:
18231127
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Functional enhancers at the gene-poor 8q24 cancer-linked locus.

Jia L, Landan G, Pomerantz M, Jaschek R, Herman P, Reich D, Yan C, Khalid O, Kantoff P, Oh W, Manak JR, Berman BP, Henderson BE, Frenkel B, Haiman CA, Freedman M, Tanay A, Coetzee GA.

PLoS Genet. 2009 Aug;5(8):e1000597. doi: 10.1371/journal.pgen.1000597. Epub 2009 Aug 14.

PMID:
19680443
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583.

Tuupanen S, Yan J, Turunen M, Gylfe AE, Kaasinen E, Li L, Eng C, Culver DA, Kalady MF, Pennison MJ, Pasche B, Manne U, de la Chapelle A, Hampel H, Henderson BE, Le Marchand L, Hautaniemi S, Askhtorab H, Smoot D, Sandler RS, Keku T, Kupfer SS, Ellis NA, Haiman CA, Taipale J, Aaltonen LA.

Cancer Genet. 2012 Jan-Feb;205(1-2):25-33. doi: 10.1016/j.cancergen.2012.01.005.

PMID:
22429595
[PubMed - indexed for MEDLINE]
Free PMC Article
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk