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Results: 1 to 20 of 97

1.

Myristoylation and membrane binding regulate c-Src stability and kinase activity.

Patwardhan P, Resh MD.

Mol Cell Biol. 2010 Sep;30(17):4094-107. doi: 10.1128/MCB.00246-10. Epub 2010 Jun 28.

PMID:
20584982
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading.

Liang X, Lu Y, Wilkes M, Neubert TA, Resh MD.

J Biol Chem. 2004 Feb 27;279(9):8133-9. Epub 2003 Dec 5.

PMID:
14660555
[PubMed - indexed for MEDLINE]
Free Article
3.

The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation.

Cowan-Jacob SW, Fendrich G, Manley PW, Jahnke W, Fabbro D, Liebetanz J, Meyer T.

Structure. 2005 Jun;13(6):861-71.

PMID:
15939018
[PubMed - indexed for MEDLINE]
Free Article
4.

Serine 6 of Lck tyrosine kinase: a critical site for Lck myristoylation, membrane localization, and function in T lymphocytes.

Yasuda K, Kosugi A, Hayashi F, Saitoh S, Nagafuku M, Mori Y, Ogata M, Hamaoka T.

J Immunol. 2000 Sep 15;165(6):3226-31.

PMID:
10975838
[PubMed - indexed for MEDLINE]
Free Article
5.

Targeting of a G alpha subunit (Gi1 alpha) and c-Src tyrosine kinase to caveolae membranes: clarifying the role of N-myristoylation.

Song KS, Sargiacomo M, Galbiati F, Parenti M, Lisanti MP.

Cell Mol Biol (Noisy-le-grand). 1997 May;43(3):293-303.

PMID:
9193783
[PubMed - indexed for MEDLINE]
6.

Myristoylation-regulated direct interaction between calcium-bound calmodulin and N-terminal region of pp60v-src.

Hayashi N, Nakagawa C, Ito Y, Takasaki A, Jinbo Y, Yamakawa Y, Titani K, Hashimoto K, Izumi Y, Matsushima N.

J Mol Biol. 2004 Apr 16;338(1):169-80.

PMID:
15050832
[PubMed - indexed for MEDLINE]
7.

Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl.

Sun J, Pedersen M, Bengtsson S, Rönnstrand L.

Exp Cell Res. 2007 Nov 1;313(18):3935-42. Epub 2007 Sep 4.

PMID:
17904548
[PubMed - indexed for MEDLINE]
8.

Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation.

Kyo S, Sada K, Qu X, Maeno K, Miah SM, Kawauchi-Kamata K, Yamamura H.

Genes Cells. 2003 Oct;8(10):825-36.

PMID:
14531861
[PubMed - indexed for MEDLINE]
10.

Src family kinases: regulation of their activities, levels and identification of new pathways.

Ingley E.

Biochim Biophys Acta. 2008 Jan;1784(1):56-65. Epub 2007 Aug 22. Review.

PMID:
17905674
[PubMed - indexed for MEDLINE]
Free Article
11.

Src-Abl tyrosine kinase chimeras: replacement of the adenine binding pocket of c-Abl with v-Src to swap nucleotide and inhibitor specificities.

Liu Y, Witucki LA, Shah K, Bishop AC, Shokat KM.

Biochemistry. 2000 Nov 28;39(47):14400-8.

PMID:
11087392
[PubMed - indexed for MEDLINE]
12.

Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14).

Lee H, Woodman SE, Engelman JA, Volonté D, Galbiati F, Kaufman HL, Lublin DM, Lisanti MP.

J Biol Chem. 2001 Sep 14;276(37):35150-8. Epub 2001 Jul 12.

PMID:
11451957
[PubMed - indexed for MEDLINE]
Free Article
13.

Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain.

Fujita A, Shishido T, Yuan Y, Inamoto E, Narumiya S, Watanabe N.

Mol Pharmacol. 2009 Jan;75(1):75-84. doi: 10.1124/mol.108.051706. Epub 2008 Oct 3.

PMID:
18835981
[PubMed - indexed for MEDLINE]
Free Article
14.

Ubiquitin-mediated degradation of active Src tyrosine kinase.

Harris KF, Shoji I, Cooper EM, Kumar S, Oda H, Howley PM.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13738-43.

PMID:
10570142
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structure-function analysis of Lyn kinase association with lipid rafts and initiation of early signaling events after Fcepsilon receptor I aggregation.

Kovárová M, Tolar P, Arudchandran R, Dráberová L, Rivera J, Dráber P.

Mol Cell Biol. 2001 Dec;21(24):8318-28.

PMID:
11713268
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.

Poghosyan Z, Robbins SM, Houslay MD, Webster A, Murphy G, Edwards DR.

J Biol Chem. 2002 Feb 15;277(7):4999-5007. Epub 2001 Dec 10.

PMID:
11741929
[PubMed - indexed for MEDLINE]
Free Article
17.

Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.

Liang X, Wisniewski D, Strife A, Shivakrupa, Clarkson B, Resh MD.

J Biol Chem. 2002 Apr 19;277(16):13732-8. Epub 2002 Feb 1.

PMID:
11825908
[PubMed - indexed for MEDLINE]
Free Article
18.

c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.

Taher TE, Tjin EP, Beuling EA, Borst J, Spaargaren M, Pals ST.

J Immunol. 2002 Oct 1;169(7):3793-800.

PMID:
12244174
[PubMed - indexed for MEDLINE]
Free Article
19.

Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.

Smith JM, Katz S, Mayer BJ.

J Biol Chem. 1999 Sep 24;274(39):27956-62.

PMID:
10488144
[PubMed - indexed for MEDLINE]
Free Article
20.

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