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Items: 1 to 20 of 108


Structure and mechanism of human DNA polymerase eta.

Biertümpfel C, Zhao Y, Kondo Y, Ramón-Maiques S, Gregory M, Lee JY, Masutani C, Lehmann AR, Hanaoka F, Yang W.

Nature. 2010 Jun 24;465(7301):1044-8. doi: 10.1038/nature09196. Erratum in: Nature. 2011 Aug 18;476(7360):360.


Structural basis for the suppression of skin cancers by DNA polymerase eta.

Silverstein TD, Johnson RE, Jain R, Prakash L, Prakash S, Aggarwal AK.

Nature. 2010 Jun 24;465(7301):1039-43. doi: 10.1038/nature09104.


DNA repair: How to accurately bypass damage.

Broyde S, Patel DJ.

Nature. 2010 Jun 24;465(7301):1023-4. doi: 10.1038/4651023a. No abstract available.


Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta.

Hendel A, Ziv O, Gueranger Q, Geacintov N, Livneh Z.

DNA Repair (Amst). 2008 Oct 1;7(10):1636-46. doi: 10.1016/j.dnarep.2008.06.008. Epub 2008 Aug 3.


Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts.

Yu SL, Johnson RE, Prakash S, Prakash L.

Mol Cell Biol. 2001 Jan;21(1):185-8.


Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta.

Johnson RE, Prakash L, Prakash S.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12359-64. Epub 2005 Aug 22.


Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.

Cordonnier AM, Fuchs RP.

Mutat Res. 1999 Oct 22;435(2):111-9. Review.


Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.

Zhao Y, Biertümpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7269-74. doi: 10.1073/pnas.1202681109. Epub 2012 Apr 23.


The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme.

Washington MT, Johnson RE, Prakash L, Prakash S.

Mol Cell Biol. 2003 Nov;23(22):8316-22.


Biochemical analysis of active site mutations of human polymerase η.

Suarez SC, Beardslee RA, Toffton SM, McCulloch SD.

Mutat Res. 2013 May-Jun;745-746:46-54. doi: 10.1016/j.mrfmmm.2013.03.001. Epub 2013 Mar 13.


Replication of a cis-syn thymine dimer at atomic resolution.

Ling H, Boudsocq F, Plosky BS, Woodgate R, Yang W.

Nature. 2003 Aug 28;424(6952):1083-7. Epub 2003 Aug 6.


DNA binding properties of human DNA polymerase eta: implications for fidelity and polymerase switching of translesion synthesis.

Kusumoto R, Masutani C, Shimmyo S, Iwai S, Hanaoka F.

Genes Cells. 2004 Dec;9(12):1139-50.


The role of DNA polymerase eta in UV mutational spectra.

Choi JH, Pfeifer GP.

DNA Repair (Amst). 2005 Feb 3;4(2):211-20.


Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis.

Trincao J, Johnson RE, Escalante CR, Prakash S, Prakash L, Aggarwal AK.

Mol Cell. 2001 Aug;8(2):417-26.


Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity.

McCulloch SD, Kokoska RJ, Masutani C, Iwai S, Hanaoka F, Kunkel TA.

Nature. 2004 Mar 4;428(6978):97-100.


Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.

Masutani C, Araki M, Yamada A, Kusumoto R, Nogimori T, Maekawa T, Iwai S, Hanaoka F.

EMBO J. 1999 Jun 15;18(12):3491-501.


Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.

Kannouche P, Broughton BC, Volker M, Hanaoka F, Mullenders LH, Lehmann AR.

Genes Dev. 2001 Jan 15;15(2):158-72.


Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct.

Johnson RE, Haracska L, Prakash S, Prakash L.

Mol Cell Biol. 2001 May;21(10):3558-63.


FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance.

Baldeck N, Janel-Bintz R, Wagner J, Tissier A, Fuchs RP, Burkovics P, Haracska L, Despras E, Bichara M, Chatton B, Cordonnier AM.

Nucleic Acids Res. 2015 Feb 27;43(4):2116-25. doi: 10.1093/nar/gkv076. Epub 2015 Feb 6.

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