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Results: 1 to 20 of 93

1.

Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells.

Wang Y, Ngo VN, Marani M, Yang Y, Wright G, Staudt LM, Downward J.

Oncogene. 2010 Aug 19;29(33):4658-70. doi: 10.1038/onc.2010.218. Epub 2010 Jun 21.

PMID:
20562906
[PubMed - indexed for MEDLINE]
2.

Oncogenic RAS alters the global and gene-specific histone modification pattern during epithelial-mesenchymal transition in colorectal carcinoma cells.

Peláez IM, Kalogeropoulou M, Ferraro A, Voulgari A, Pankotai T, Boros I, Pintzas A.

Int J Biochem Cell Biol. 2010 Jun;42(6):911-20. doi: 10.1016/j.biocel.2010.01.024. Epub 2010 Jan 28.

PMID:
20109579
[PubMed - indexed for MEDLINE]
3.

Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium.

Keller JW, Franklin JL, Graves-Deal R, Friedman DB, Whitwell CW, Coffey RJ.

J Cell Physiol. 2007 Mar;210(3):740-9.

PMID:
17133351
[PubMed - indexed for MEDLINE]
4.

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.

Steckel M, Molina-Arcas M, Weigelt B, Marani M, Warne PH, Kuznetsov H, Kelly G, Saunders B, Howell M, Downward J, Hancock DC.

Cell Res. 2012 Aug;22(8):1227-45. doi: 10.1038/cr.2012.82. Epub 2012 May 22.

PMID:
22613949
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Colorectal tumors are effectively eradicated by combined inhibition of {beta}-catenin, KRAS, and the oncogenic transcription factor ITF2.

Mologni L, Dekhil H, Ceccon M, Purgante S, Lan C, Cleris L, Magistroni V, Formelli F, Gambacorti-Passerini CB.

Cancer Res. 2010 Sep 15;70(18):7253-63. doi: 10.1158/0008-5472.CAN-10-1108. Epub 2010 Sep 7.

PMID:
20823162
[PubMed - indexed for MEDLINE]
Free Article
6.

TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.

Voulgari A, Voskou S, Tora L, Davidson I, Sasazuki T, Shirasawa S, Pintzas A.

Mol Cancer Res. 2008 Jun;6(6):1071-83. doi: 10.1158/1541-7786.MCR-07-0375.

PMID:
18567809
[PubMed - indexed for MEDLINE]
Free Article
7.

Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer.

Seiden-Long IM, Brown KR, Shih W, Wigle DA, Radulovich N, Jurisica I, Tsao MS.

Oncogene. 2006 Jan 5;25(1):91-102.

PMID:
16158056
[PubMed - indexed for MEDLINE]
8.

Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition.

van Houdt WJ, de Bruijn MT, Emmink BL, Raats D, Hoogwater FJ, Borel Rinkes IH, Kranenburg O.

Cell Oncol. 2010 Jan 1;32(4):245-57. doi: 10.3233/CLO-2010-0521.

PMID:
20413844
[PubMed - indexed for MEDLINE]
9.

Interplay between oncogenic K-Ras and wild-type H-Ras in Caco2 cell transformation.

Ikonomou G, Kostourou V, Shirasawa S, Sasazuki T, Samiotaki M, Panayotou G.

J Proteomics. 2012 Sep 18;75(17):5356-69. doi: 10.1016/j.jprot.2012.06.038. Epub 2012 Jul 16.

PMID:
22800643
[PubMed - indexed for MEDLINE]
10.

Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS.

Stelniec-Klotz I, Legewie S, Tchernitsa O, Witzel F, Klinger B, Sers C, Herzel H, Blüthgen N, Schäfer R.

Mol Syst Biol. 2012;8:601. doi: 10.1038/msb.2012.32.

PMID:
22864383
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

BMC Cancer. 2008 Jul 2;8:189. doi: 10.1186/1471-2407-8-189.

PMID:
18597688
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines.

Yoshida Y, Tsunoda T, Doi K, Tanaka Y, Fujimoto T, Machida T, Ota T, Koyanagi M, Takashima Y, Sasazuki T, Kuroki M, Iwasaki A, Shirasawa S.

Anticancer Res. 2011 Jul;31(7):2535-9.

PMID:
21873171
[PubMed - indexed for MEDLINE]
13.

Human ZNF312b promotes the progression of gastric cancer by transcriptional activation of the K-ras gene.

Song IS, Oh NS, Kim HT, Ha GH, Jeong SY, Kim JM, Kim DI, Yoo HS, Kim CH, Kim NS.

Cancer Res. 2009 Apr 1;69(7):3131-9. doi: 10.1158/0008-5472.CAN-08-2240. Epub 2009 Mar 24. Erratum in: Cancer Res. 2009 May 1;69(9):4092.

PMID:
19318583
[PubMed - indexed for MEDLINE]
Free Article
14.

RAS oncogenic signal upregulates EZH2 in pancreatic cancer.

Fujii S, Fukamachi K, Tsuda H, Ito K, Ito Y, Ochiai A.

Biochem Biophys Res Commun. 2012 Jan 20;417(3):1074-9. doi: 10.1016/j.bbrc.2011.12.099. Epub 2011 Dec 26.

PMID:
22222375
[PubMed - indexed for MEDLINE]
15.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.

Cell. 2009 May 29;137(5):835-48. doi: 10.1016/j.cell.2009.05.006.

PMID:
19490893
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Oncogenic KRAS regulates miR-200c and miR-221/222 in a 3D-specific manner in colorectal cancer cells.

Tsunoda T, Takashima Y, Yoshida Y, Doi K, Tanaka Y, Fujimoto T, Machida T, Ota T, Koyanagi M, Kuroki M, Sasazuki T, Shirasawa S.

Anticancer Res. 2011 Jul;31(7):2453-9.

PMID:
21873159
[PubMed - indexed for MEDLINE]
17.

Human pancreatic duct epithelial cell model for KRAS transformation.

Radulovich N, Qian JY, Tsao MS.

Methods Enzymol. 2008;439:1-13. doi: 10.1016/S0076-6879(07)00401-6.

PMID:
18374152
[PubMed - indexed for MEDLINE]
18.

TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells.

Luu C, Heinrich EL, Duldulao M, Arrington AK, Fakih M, Garcia-Aguilar J, Kim J.

PLoS One. 2013 Aug 1;8(8):e70604. doi: 10.1371/journal.pone.0070604. Print 2013.

PMID:
23936455
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.

Larriba MJ, Martín-Villar E, García JM, Pereira F, Peña C, de Herreros AG, Bonilla F, Muñoz A.

Carcinogenesis. 2009 Aug;30(8):1459-68. doi: 10.1093/carcin/bgp140. Epub 2009 Jun 5.

PMID:
19502595
[PubMed - indexed for MEDLINE]
Free Article
20.

Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis.

Lemieux E, Bergeron S, Durand V, Asselin C, Saucier C, Rivard N.

Int J Cancer. 2009 Oct 1;125(7):1575-86. doi: 10.1002/ijc.24485.

PMID:
19462441
[PubMed - indexed for MEDLINE]
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