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Results: 1 to 20 of 361

1.

Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling.

Yahiro K, Morinaga N, Moss J, Noda M.

Microb Pathog. 2010 Oct;49(4):153-63. doi: 10.1016/j.micpath.2010.05.007. Epub 2010 Jun 2.

PMID:
20561923
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Novel subtilase cytotoxin produced by Shiga-toxigenic Escherichia coli induces apoptosis in vero cells via mitochondrial membrane damage.

Matsuura G, Morinaga N, Yahiro K, Komine R, Moss J, Yoshida H, Noda M.

Infect Immun. 2009 Jul;77(7):2919-24. doi: 10.1128/IAI.01510-08. Epub 2009 Apr 20.

PMID:
19380466
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Escherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/Bak.

May KL, Paton JC, Paton AW.

Infect Immun. 2010 Nov;78(11):4691-6. doi: 10.1128/IAI.00801-10. Epub 2010 Aug 16.

PMID:
20713620
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells.

Yahiro K, Tsutsuki H, Ogura K, Nagasawa S, Moss J, Noda M.

Infect Immun. 2012 May;80(5):1803-14. doi: 10.1128/IAI.06164-11. Epub 2012 Feb 21.

PMID:
22354021
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.

Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.

J Biol Chem. 2006 Apr 21;281(16):11250-9. Epub 2006 Jan 25.

PMID:
16436379
[PubMed - indexed for MEDLINE]
Free Article
6.

Identification of subtilase cytotoxin (SubAB) receptors whose signaling, in association with SubAB-induced BiP cleavage, is responsible for apoptosis in HeLa cells.

Yahiro K, Satoh M, Morinaga N, Tsutsuki H, Ogura K, Nagasawa S, Nomura F, Moss J, Noda M.

Infect Immun. 2011 Feb;79(2):617-27. doi: 10.1128/IAI.01020-10. Epub 2010 Nov 22.

PMID:
21098100
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.

Kim MJ, Lee KH, Lee SJ.

FEBS J. 2008 May;275(9):2096-108. doi: 10.1111/j.1742-4658.2008.06363.x. Epub 2008 Mar 28.

PMID:
18373696
[PubMed - indexed for MEDLINE]
8.

Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.

Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2006 Mar 17;281(11):7049-59. Epub 2006 Jan 12.

PMID:
16410245
[PubMed - indexed for MEDLINE]
Free Article
9.

Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.

Siu WP, Pun PB, Latchoumycandane C, Boelsterli UA.

Toxicol Appl Pharmacol. 2008 Mar 15;227(3):451-61. doi: 10.1016/j.taap.2007.11.030. Epub 2007 Dec 14.

PMID:
18191430
[PubMed - indexed for MEDLINE]
10.

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ.

Science. 2006 Apr 28;312(5773):572-6.

PMID:
16645094
[PubMed - indexed for MEDLINE]
Free Article
11.

The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.

Pagliari LJ, Kuwana T, Bonzon C, Newmeyer DD, Tu S, Beere HM, Green DR.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17975-80. Epub 2005 Dec 5.

PMID:
16330765
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A Bax/Bak-independent mechanism of cytochrome c release.

Mizuta T, Shimizu S, Matsuoka Y, Nakagawa T, Tsujimoto Y.

J Biol Chem. 2007 Jun 1;282(22):16623-30. Epub 2007 Apr 4.

PMID:
17409097
[PubMed - indexed for MEDLINE]
Free Article
13.

Apoptosis-associated mitochondrial outer membrane permeabilization assays.

Arnoult D.

Methods. 2008 Mar;44(3):229-34. doi: 10.1016/j.ymeth.2007.11.003. Review.

PMID:
18314053
[PubMed - indexed for MEDLINE]
14.

Characterization of Cholix toxin-induced apoptosis in HeLa cells.

Ogura K, Yahiro K, Tsutsuki H, Nagasawa S, Yamasaki S, Moss J, Noda M.

J Biol Chem. 2011 Oct 28;286(43):37207-15. doi: 10.1074/jbc.M111.246504. Epub 2011 Sep 8.

PMID:
21903588
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death.

Kim MJ, Park MT, Yoon CH, Byun JY, Lee SJ.

Biochem Biophys Res Commun. 2008 May 30;370(2):353-8. doi: 10.1016/j.bbrc.2008.03.084. Epub 2008 Mar 25.

PMID:
18371298
[PubMed - indexed for MEDLINE]
16.

Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells.

Shawgo ME, Shelton SN, Robertson JD.

J Biol Chem. 2008 Dec 19;283(51):35532-8. doi: 10.1074/jbc.M807656200. Epub 2008 Oct 15.

PMID:
18927073
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.

Wan KF, Chan SL, Sukumaran SK, Lee MC, Yu VC.

J Biol Chem. 2008 Mar 28;283(13):8423-33. doi: 10.1074/jbc.M707687200. Epub 2008 Jan 29.

PMID:
18230621
[PubMed - indexed for MEDLINE]
Free PMC Article
18.
19.

Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.

Lim do Y, Park JH.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8. doi: 10.1152/ajpgi.90490.2008. Epub 2009 Mar 5.

PMID:
19264955
[PubMed - indexed for MEDLINE]
Free Article
20.

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K.

Sundararajan R, Cuconati A, Nelson D, White E.

J Biol Chem. 2001 Nov 30;276(48):45120-7. Epub 2001 Sep 24.

PMID:
11571294
[PubMed - indexed for MEDLINE]
Free Article

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