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Items: 1 to 20 of 104


Heterologous immunity between viruses.

Welsh RM, Che JW, Brehm MA, Selin LK.

Immunol Rev. 2010 May;235(1):244-66. doi: 10.1111/j.0105-2896.2010.00897.x. Review.


T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.

Brehm MA, Pinto AK, Daniels KA, Schneck JP, Welsh RM, Selin LK.

Nat Immunol. 2002 Jul;3(7):627-34. Epub 2002 Jun 3.


Direct visualization of cross-reactive effector and memory allo-specific CD8 T cells generated in response to viral infections.

Brehm MA, Markees TG, Daniels KA, Greiner DL, Rossini AA, Welsh RM.

J Immunol. 2003 Apr 15;170(8):4077-86.


Increased Immune Response Variability during Simultaneous Viral Coinfection Leads to Unpredictability in CD8 T Cell Immunity and Pathogenesis.

Kenney LL, Cornberg M, Chen AT, Emonet S, de la Torre JC, Selin LK.

J Virol. 2015 Nov;89(21):10786-801. doi: 10.1128/JVI.01432-15. Epub 2015 Aug 12.


Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells.

Ziegler S, Skibbe K, Walker A, Ke X, Heinemann FM, Heinold A, Mok JY, van Esch WJ, Yang D, W├Âlfl M, Timm J.

J Virol. 2014 Oct;88(19):11080-90. doi: 10.1128/JVI.01590-14. Epub 2014 Jul 9.


Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.

Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K.

PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039.


Private specificities of CD8 T cell responses control patterns of heterologous immunity.

Kim SK, Cornberg M, Wang XZ, Chen HD, Selin LK, Welsh RM.

J Exp Med. 2005 Feb 21;201(4):523-33. Epub 2005 Feb 14.


Altered effector functions of virus-specific and virus cross-reactive CD8+ T cells in mice immunized with related flaviviruses.

Trobaugh DW, Yang L, Ennis FA, Green S.

Eur J Immunol. 2010 May;40(5):1315-27. doi: 10.1002/eji.200839108.


CD8 memory T cells: cross-reactivity and heterologous immunity.

Selin LK, Cornberg M, Brehm MA, Kim SK, Calcagno C, Ghersi D, Puzone R, Celada F, Welsh RM.

Semin Immunol. 2004 Oct;16(5):335-47. Review.


The privacy of T cell memory to viruses.

Welsh RM, Kim SK, Cornberg M, Clute SC, Selin LK, Naumov YN.

Curr Top Microbiol Immunol. 2006;311:117-53. Review.


CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections.

Cornberg M, Clute SC, Watkin LB, Saccoccio FM, Kim SK, Naumov YN, Brehm MA, Aslan N, Welsh RM, Selin LK.

J Immunol. 2010 Mar 15;184(6):2825-38. doi: 10.4049/jimmunol.0902168. Epub 2010 Feb 17.


Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes.

Clute SC, Naumov YN, Watkin LB, Aslan N, Sullivan JL, Thorley-Lawson DA, Luzuriaga K, Welsh RM, Puzone R, Celada F, Selin LK.

J Immunol. 2010 Dec 1;185(11):6753-64. doi: 10.4049/jimmunol.1000812. Epub 2010 Nov 3.


Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells.

Shen ZT, Nguyen TT, Daniels KA, Welsh RM, Stern LJ.

J Immunol. 2013 Nov 15;191(10):5139-52. doi: 10.4049/jimmunol.1300852. Epub 2013 Oct 14.


Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses.

Selin LK, Lin MY, Kraemer KA, Pardoll DM, Schneck JP, Varga SM, Santolucito PA, Pinto AK, Welsh RM.

Immunity. 1999 Dec;11(6):733-42.


Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity.

Selin LK, Brehm MA, Naumov YN, Cornberg M, Kim SK, Clute SC, Welsh RM.

Immunol Rev. 2006 Jun;211:164-81. Review.


The two faces of heterologous immunity: protection or immunopathology.

Sharma S, Thomas PG.

J Leukoc Biol. 2014 Mar;95(3):405-16. doi: 10.1189/jlb.0713386. Epub 2013 Nov 8. Review.


Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity.

Cornberg M, Chen AT, Wilkinson LA, Brehm MA, Kim SK, Calcagno C, Ghersi D, Puzone R, Celada F, Welsh RM, Selin LK.

J Clin Invest. 2006 May;116(5):1443-56. Epub 2006 Apr 13. Erratum in: J Clin Invest. 2007 May;117(5):1450.

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