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Items: 1 to 20 of 145

1.

Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease.

Biju K, Zhou Q, Li G, Imam SZ, Roberts JL, Morgan WW, Clark RA, Li S.

Mol Ther. 2010 Aug;18(8):1536-44. doi: 10.1038/mt.2010.107. Epub 2010 Jun 8.

2.

Bone marrow-derived microglia-based neurturin delivery protects against dopaminergic neurodegeneration in a mouse model of Parkinson's disease.

Biju KC, Santacruz RA, Chen C, Zhou Q, Yao J, Rohrabaugh SL, Clark RA, Roberts JL, Phillips KA, Imam SZ, Li S.

Neurosci Lett. 2013 Feb 22;535:24-9. doi: 10.1016/j.neulet.2012.12.034. Epub 2013 Jan 4.

3.

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, Brown WD, Holden JE, Pyzalski R, Taylor MD, Carvey P, Ling Z, Trono D, Hantraye P, Déglon N, Aebischer P.

Science. 2000 Oct 27;290(5492):767-73.

4.

Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.

Xu G, Xiong Z, Yong Y, Wang Z, Ke Z, Xia Z, Hu Y.

Neuroscience. 2010 Apr 28;167(1):174-84. doi: 10.1016/j.neuroscience.2010.01.048. Epub 2010 Feb 1.

PMID:
20123001
5.

The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease.

Tanriover G, Seval-Celik Y, Ozsoy O, Akkoyunlu G, Savcioglu F, Hacioglu G, Demir N, Agar A.

Folia Histochem Cytobiol. 2010 Sep 30;48(3):434-41. doi: 10.2478/v10042-010-0047-6.

6.

Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor.

Sun X, Xiong Z, Zhang Y, Meng Y, Xu G, Xia Z, Li J, Zhang R, Ke Z, Xia Z, Hu Y.

J Neurochem. 2012 Mar;120(6):1072-83. doi: 10.1111/j.1471-4159.2011.07635.x. Epub 2012 Feb 6.

7.

Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation.

Villadiego J, Méndez-Ferrer S, Valdés-Sánchez T, Silos-Santiago I, Fariñas I, López-Barneo J, Toledo-Aral JJ.

J Neurosci. 2005 Apr 20;25(16):4091-8.

8.

Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery.

Drinkut A, Tereshchenko Y, Schulz JB, Bähr M, Kügler S.

Mol Ther. 2012 Mar;20(3):534-43. doi: 10.1038/mt.2011.249. Epub 2011 Nov 15.

9.

Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease.

Dietz GP, Valbuena PC, Dietz B, Meuer K, Müeller P, Weishaupt JH, Bähr M.

Brain Res. 2006 Apr 12;1082(1):61-6.

PMID:
16703672
10.

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo.

Tomac A, Lindqvist E, Lin LF, Ogren SO, Young D, Hoffer BJ, Olson L.

Nature. 1995 Jan 26;373(6512):335-9.

PMID:
7830766
11.

GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action.

Schober A, Peterziel H, von Bartheld CS, Simon H, Krieglstein K, Unsicker K.

Neurobiol Dis. 2007 Feb;25(2):378-91. Epub 2006 Dec 1.

PMID:
17141511
13.
14.

GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.

Decressac M, Ulusoy A, Mattsson B, Georgievska B, Romero-Ramos M, Kirik D, Björklund A.

Brain. 2011 Aug;134(Pt 8):2302-11. doi: 10.1093/brain/awr149. Epub 2011 Jun 28.

16.

Doxycycline-regulated co-expression of GDNF and TH in PC12 cells.

Wang JJ, Zhang T, Niu DB, Wang K, Li KR, Xue B, Wang XM.

Neurosci Lett. 2006 Jun 19;401(1-2):142-5. Epub 2006 Apr 3.

PMID:
16584838
17.

Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease.

Wang L, Muramatsu S, Lu Y, Ikeguchi K, Fujimoto K, Okada T, Mizukami H, Hanazono Y, Kume A, Urano F, Ichinose H, Nagatsu T, Nakano I, Ozawa K.

Gene Ther. 2002 Mar;9(6):381-9.

18.

Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease.

Brizard M, Carcenac C, Bemelmans AP, Feuerstein C, Mallet J, Savasta M.

Neurobiol Dis. 2006 Jan;21(1):90-101. Epub 2005 Aug 9.

PMID:
16084732
19.

Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.

Palfi S, Leventhal L, Chu Y, Ma SY, Emborg M, Bakay R, Déglon N, Hantraye P, Aebischer P, Kordower JH.

J Neurosci. 2002 Jun 15;22(12):4942-54.

20.
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