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Items: 1 to 20 of 101

1.

Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent.

Tao J, Chen S, Yang T, Dawson B, Munivez E, Bertin T, Lee B.

J Bone Miner Res. 2010 Oct;25(10):2175-83. doi: 10.1002/jbmr.115.

2.

Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9.

Chen S, Tao J, Bae Y, Jiang MM, Bertin T, Chen Y, Yang T, Lee B.

J Bone Miner Res. 2013 Mar;28(3):649-59. doi: 10.1002/jbmr.1770.

3.

Loss of the Notch effector RBPJ promotes tumorigenesis.

Kulic I, Robertson G, Chang L, Baker JH, Lockwood WW, Mok W, Fuller M, Fournier M, Wong N, Chou V, Robinson MD, Chun HJ, Gilks B, Kempkes B, Thomson TA, Hirst M, Minchinton AI, Lam WL, Jones S, Marra M, Karsan A.

J Exp Med. 2015 Jan 12;212(1):37-52. doi: 10.1084/jem.20121192. Epub 2014 Dec 15.

4.

Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development.

Kohn A, Dong Y, Mirando AJ, Jesse AM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Development. 2012 Mar;139(6):1198-212. doi: 10.1242/dev.070649.

5.

Dimorphic effects of Notch signaling in bone homeostasis.

Engin F, Yao Z, Yang T, Zhou G, Bertin T, Jiang MM, Chen Y, Wang L, Zheng H, Sutton RE, Boyce BF, Lee B.

Nat Med. 2008 Mar;14(3):299-305. doi: 10.1038/nm1712. Epub 2008 Feb 24.

6.

Dynamic binding of RBPJ is determined by Notch signaling status.

Castel D, Mourikis P, Bartels SJ, Brinkman AB, Tajbakhsh S, Stunnenberg HG.

Genes Dev. 2013 May 1;27(9):1059-71. doi: 10.1101/gad.211912.112. Erratum in: Genes Dev. 2013 Jun 1;27(11):1313.

7.

Rbpj-κ mediated Notch signaling plays a critical role in development of hypothalamic Kisspeptin neurons.

Biehl MJ, Raetzman LT.

Dev Biol. 2015 Oct 15;406(2):235-46. doi: 10.1016/j.ydbio.2015.08.016. Epub 2015 Aug 28.

PMID:
26318021
8.

Rbpj regulates development of prosensory cells in the mammalian inner ear.

Yamamoto N, Chang W, Kelley MW.

Dev Biol. 2011 May 15;353(2):367-79. doi: 10.1016/j.ydbio.2011.03.016. Epub 2011 Mar 21.

9.

Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.

Swarnkar G, Karuppaiah K, Mbalaviele G, Chen TH, Abu-Amer Y.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):154-9. doi: 10.1073/pnas.1415213112. Epub 2014 Dec 22.

10.

Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.

Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW.

Mol Cell Biol. 2014 Feb;34(4):653-63. doi: 10.1128/MCB.01408-13. Epub 2013 Dec 2.

11.

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.

Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Development. 2010 May;137(9):1461-71. doi: 10.1242/dev.042911. Epub 2010 Mar 24.

12.

Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.

Riesenberg AN, Liu Z, Kopan R, Brown NL.

J Neurosci. 2009 Oct 14;29(41):12865-77. doi: 10.1523/JNEUROSCI.3382-09.2009.

13.

Osteoblast lineage-specific effects of notch activation in the skeleton.

Canalis E, Parker K, Feng JQ, Zanotti S.

Endocrinology. 2013 Feb;154(2):623-34. doi: 10.1210/en.2012-1732. Epub 2012 Dec 28.

14.

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.

Nielsen CM, Cuervo H, Ding VW, Kong Y, Huang EJ, Wang RA.

Development. 2014 Oct;141(19):3782-92. doi: 10.1242/dev.108951. Epub 2014 Sep 10.

15.

Role of the RAM domain and ankyrin repeats on notch signaling and activity in cells of osteoblastic lineage.

Deregowski V, Gazzerro E, Priest L, Rydziel S, Canalis E.

J Bone Miner Res. 2006 Aug;21(8):1317-26.

16.

DNA methylation of a GC repressor element in the smooth muscle myosin heavy chain promoter facilitates binding of the Notch-associated transcription factor, RBPJ/CSL1.

Rozenberg JM, Tesfu DB, Musunuri S, Taylor JM, Mack CP.

Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2624-31. doi: 10.1161/ATVBAHA.114.304634. Epub 2014 Oct 16.

17.

Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj.

Walter TJ, Vanderpool C, Cast AE, Huppert SS.

Am J Pathol. 2014 May;184(5):1479-88. doi: 10.1016/j.ajpath.2014.01.030. Epub 2014 Mar 13.

18.

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche.

Garcia TX, Farmaha JK, Kow S, Hofmann MC.

Development. 2014 Dec;141(23):4468-78. doi: 10.1242/dev.113969. Epub 2014 Nov 18.

19.

Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells.

Maillard I, Koch U, Dumortier A, Shestova O, Xu L, Sai H, Pross SE, Aster JC, Bhandoola A, Radtke F, Pear WS.

Cell Stem Cell. 2008 Apr 10;2(4):356-66. doi: 10.1016/j.stem.2008.02.011.

20.

Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.

Canalis E, Zanotti S, Smerdel-Ramoya A.

Bone. 2014 Jul;64:273-80. doi: 10.1016/j.bone.2014.04.028. Epub 2014 May 2.

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