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BpeAB-OprB, a multidrug efflux pump in Burkholderia pseudomallei.

Chan YY, Tan TM, Ong YM, Chua KL.

Antimicrob Agents Chemother. 2004 Apr;48(4):1128-35.


In vitro activity of cethromycin against Burkholderia pseudomallei and investigation of mechanism of resistance.

Mima T, Schweizer HP, Xu ZQ.

J Antimicrob Chemother. 2011 Jan;66(1):73-8. doi: 10.1093/jac/dkq391. Epub 2010 Oct 21.


Growth-related changes in intracellular spermidine and its effect on efflux pump expression and quorum sensing in Burkholderia pseudomallei.

Chan YY, Chua KL.

Microbiology. 2010 Apr;156(Pt 4):1144-54. doi: 10.1099/mic.0.032888-0. Epub 2009 Dec 24.


Control of quorum sensing by a Burkholderia pseudomallei multidrug efflux pump.

Chan YY, Bian HS, Tan TM, Mattmann ME, Geske GD, Igarashi J, Hatano T, Suga H, Blackwell HE, Chua KL.

J Bacteriol. 2007 Jun;189(11):4320-4. Epub 2007 Mar 23.


Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei.

Moore RA, DeShazer D, Reckseidler S, Weissman A, Woods DE.

Antimicrob Agents Chemother. 1999 Mar;43(3):465-70.


Expression of resistance-nodulation-cell-division efflux pumps in commonly used Burkholderia pseudomallei strains and clinical isolates from northern Australia.

Kumar A, Mayo M, Trunck LA, Cheng AC, Currie BJ, Schweizer HP.

Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S145-51. doi: 10.1016/S0035-9203(08)70032-4.


Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis.

Biot FV, Lopez MM, Poyot T, Neulat-Ripoll F, Lignon S, Caclard A, Thibault FM, Peinnequin A, Pag├Ęs JM, Valade E.

PLoS One. 2013 Dec 27;8(12):e84068. doi: 10.1371/journal.pone.0084068. eCollection 2013.


Primary mechanisms mediating aminoglycoside resistance in the multidrug-resistant Pseudomonas aeruginosa clinical isolate PA7.

Morita Y, Tomida J, Kawamura Y.

Microbiology. 2012 Apr;158(Pt 4):1071-83. doi: 10.1099/mic.0.054320-0. Epub 2012 Jan 27.


Efflux-mediated resistance to tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1.

Dean CR, Visalli MA, Projan SJ, Sum PE, Bradford PA.

Antimicrob Agents Chemother. 2003 Mar;47(3):972-8.


MexXY-OprM efflux pump is required for antagonism of aminoglycosides by divalent cations in Pseudomonas aeruginosa.

Mao W, Warren MS, Lee A, Mistry A, Lomovskaya O.

Antimicrob Agents Chemother. 2001 Jul;45(7):2001-7.


N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei.

Gamage AM, Shui G, Wenk MR, Chua KL.

Microbiology. 2011 Apr;157(Pt 4):1176-86. doi: 10.1099/mic.0.046540-0. Epub 2011 Jan 20.


Aminoglycoside efflux in Pseudomonas aeruginosa: involvement of novel outer membrane proteins.

Jo JT, Brinkman FS, Hancock RE.

Antimicrob Agents Chemother. 2003 Mar;47(3):1101-11.


Molecular basis of rare aminoglycoside susceptibility and pathogenesis of Burkholderia pseudomallei clinical isolates from Thailand.

Trunck LA, Propst KL, Wuthiekanun V, Tuanyok A, Beckstrom-Sternberg SM, Beckstrom-Sternberg JS, Peacock SJ, Keim P, Dow SW, Schweizer HP.

PLoS Negl Trop Dis. 2009 Sep 22;3(9):e519. doi: 10.1371/journal.pntd.0000519.


Active efflux influences the potency of quorum sensing inhibitors in Pseudomonas aeruginosa.

Moore JD, Gerdt JP, Eibergen NR, Blackwell HE.

Chembiochem. 2014 Feb 10;15(3):435-42. doi: 10.1002/cbic.201300701. Epub 2014 Jan 29. Erratum in: Chembiochem. 2014 Mar 21;15(5):634.


Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.

Sugimura M, Maseda H, Hanaki H, Nakae T.

Antimicrob Agents Chemother. 2008 Nov;52(11):4141-4. doi: 10.1128/AAC.00511-08. Epub 2008 Aug 1.


Burkholderia pseudomallei isolates from Sarawak, Malaysian Borneo, are predominantly susceptible to aminoglycosides and macrolides.

Podin Y, Sarovich DS, Price EP, Kaestli M, Mayo M, Hii K, Ngian H, Wong S, Wong I, Wong J, Mohan A, Ooi M, Fam T, Wong J, Tuanyok A, Keim P, Giffard PM, Currie BJ.

Antimicrob Agents Chemother. 2014;58(1):162-6. doi: 10.1128/AAC.01842-13. Epub 2013 Oct 21.


Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa.

Maseda H, Yoneyama H, Nakae T.

Antimicrob Agents Chemother. 2000 Mar;44(3):658-64.

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