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Results: 1 to 20 of 95

1.

Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly.

Isaacs MJ, Kawakami Y, Allendorph GP, Yoon BH, Izpisua Belmonte JC, Choe S.

Mol Endocrinol. 2010 Jul;24(7):1469-77. doi: 10.1210/me.2009-0496. Epub 2010 May 19.

PMID:
20484413
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.

Kotzsch A, Nickel J, Seher A, Heinecke K, van Geersdaele L, Herrmann T, Sebald W, Mueller TD.

J Biol Chem. 2008 Feb 29;283(9):5876-87. Epub 2007 Dec 26.

PMID:
18160401
[PubMed - indexed for MEDLINE]
Free Article
3.

Crystal structure of BMP-9 and functional interactions with pro-region and receptors.

Brown MA, Zhao Q, Baker KA, Naik C, Chen C, Pukac L, Singh M, Tsareva T, Parice Y, Mahoney A, Roschke V, Sanyal I, Choe S.

J Biol Chem. 2005 Jul 1;280(26):25111-8. Epub 2005 Apr 25.

PMID:
15851468
[PubMed - indexed for MEDLINE]
Free Article
4.

BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors.

Allendorph GP, Isaacs MJ, Kawakami Y, Izpisua Belmonte JC, Choe S.

Biochemistry. 2007 Oct 30;46(43):12238-47. Epub 2007 Oct 9. Erratum in: Biochemistry. 2007 Oct 30;46(43):12246.

PMID:
17924656
[PubMed - indexed for MEDLINE]
5.

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins.

Heinecke K, Seher A, Schmitz W, Mueller TD, Sebald W, Nickel J.

BMC Biol. 2009 Sep 7;7:59. doi: 10.1186/1741-7007-7-59.

PMID:
19735544
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structure of the ternary signaling complex of a TGF-beta superfamily member.

Allendorph GP, Vale WW, Choe S.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7643-8. Epub 2006 May 3.

PMID:
16672363
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signaling.

Marom B, Heining E, Knaus P, Henis YI.

J Biol Chem. 2011 Jun 3;286(22):19287-96. doi: 10.1074/jbc.M110.210377. Epub 2011 Apr 6.

PMID:
21471205
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Identification of the ligand-binding site of the BMP type IA receptor for BMP-4.

Hatta T, Konishi H, Katoh E, Natsume T, Ueno N, Kobayashi Y, Yamazaki T.

Biopolymers. 2000;55(5):399-406.

PMID:
11241215
[PubMed - indexed for MEDLINE]
9.

Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells.

Yu PB, Beppu H, Kawai N, Li E, Bloch KD.

J Biol Chem. 2005 Jul 1;280(26):24443-50. Epub 2005 May 9.

PMID:
15883158
[PubMed - indexed for MEDLINE]
Free Article
10.

Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis.

Little SC, Mullins MC.

Nat Cell Biol. 2009 May;11(5):637-43. doi: 10.1038/ncb1870. Epub 2009 Apr 19.

PMID:
19377468
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.

Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD.

BMC Struct Biol. 2007 Feb 12;7:6.

PMID:
17295905
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

Paradis F, Novak S, Murdoch GK, Dyck MK, Dixon WT, Foxcroft GR.

Reproduction. 2009 Jul;138(1):115-29. doi: 10.1530/REP-08-0538. Epub 2009 Apr 9.

PMID:
19359354
[PubMed - indexed for MEDLINE]
Free Article
13.

Crystal structure of the BMP-2-BRIA ectodomain complex.

Kirsch T, Sebald W, Dreyer MK.

Nat Struct Biol. 2000 Jun;7(6):492-6.

PMID:
10881198
[PubMed - indexed for MEDLINE]
14.
15.

Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily.

Radaev S, Zou Z, Huang T, Lafer EM, Hinck AP, Sun PD.

J Biol Chem. 2010 May 7;285(19):14806-14. doi: 10.1074/jbc.M109.079921. Epub 2010 Mar 5.

PMID:
20207738
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly.

Greenwald J, Groppe J, Gray P, Wiater E, Kwiatkowski W, Vale W, Choe S.

Mol Cell. 2003 Mar;11(3):605-17.

PMID:
12667445
[PubMed - indexed for MEDLINE]
Free Article
17.

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis YI, Knaus P.

J Biol Chem. 2002 Feb 15;277(7):5330-8. Epub 2001 Nov 19.

PMID:
11714695
[PubMed - indexed for MEDLINE]
Free Article
18.

The crystal structure of the BMP-2:BMPR-IA complex and the generation of BMP-2 antagonists.

Nickel J, Dreyer MK, Kirsch T, Sebald W.

J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 1):S7-14. Review.

PMID:
11263668
[PubMed - indexed for MEDLINE]
19.

Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor.

Persson U, Souchelnytskyi S, Franzén P, Miyazono K, ten Dijke P, Heldin CH.

J Biol Chem. 1997 Aug 22;272(34):21187-94.

PMID:
9261125
[PubMed - indexed for MEDLINE]
Free Article
20.

Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors.

Gilboa L, Nohe A, Geissendörfer T, Sebald W, Henis YI, Knaus P.

Mol Biol Cell. 2000 Mar;11(3):1023-35.

PMID:
10712517
[PubMed - indexed for MEDLINE]
Free PMC Article

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